IL114715A - Intermediate compounds for ring-substituted 2-amino-1, 2, 3, 4-tetrahydronaphthalenes and 3-aminochromanes - Google Patents

Intermediate compounds for ring-substituted 2-amino-1, 2, 3, 4-tetrahydronaphthalenes and 3-aminochromanes

Info

Publication number
IL114715A
IL114715A IL11471590A IL11471590A IL114715A IL 114715 A IL114715 A IL 114715A IL 11471590 A IL11471590 A IL 11471590A IL 11471590 A IL11471590 A IL 11471590A IL 114715 A IL114715 A IL 114715A
Authority
IL
Israel
Prior art keywords
alkyl
substituted
aryl
tetrahydronaphthalenes
amino
Prior art date
Application number
IL11471590A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL114715A publication Critical patent/IL114715A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/36—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atoms of the amino groups bound to hydrogen atoms or to carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/38—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with the sulfur atom of the thio group bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL11471590A 1989-02-27 1990-02-20 Intermediate compounds for ring-substituted 2-amino-1, 2, 3, 4-tetrahydronaphthalenes and 3-aminochromanes IL114715A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31575289A 1989-02-27 1989-02-27
IL109647A IL109647A (en) 1989-02-27 1990-02-20 Intermediate compounds for ring-substituted 2-amino-1, 2, 3, 4-tetra- hydronaphthalenes and 3-aminochromanes
IL9346490A IL93464A (en) 1989-02-27 1990-02-20 2-Amino-1,2,3,4-Tetrahydronaplanin and 3 aminochromes with a transformed ring, a process for their preparation and pharmaceutical preparations containing them

Publications (1)

Publication Number Publication Date
IL114715A true IL114715A (en) 1997-01-10

Family

ID=23225899

Family Applications (5)

Application Number Title Priority Date Filing Date
IL109647A IL109647A (en) 1989-02-27 1990-02-20 Intermediate compounds for ring-substituted 2-amino-1, 2, 3, 4-tetra- hydronaphthalenes and 3-aminochromanes
IL9346490A IL93464A (en) 1989-02-27 1990-02-20 2-Amino-1,2,3,4-Tetrahydronaplanin and 3 aminochromes with a transformed ring, a process for their preparation and pharmaceutical preparations containing them
IL11471590A IL114715A (en) 1989-02-27 1990-02-20 Intermediate compounds for ring-substituted 2-amino-1, 2, 3, 4-tetrahydronaphthalenes and 3-aminochromanes
IL10964794A IL109647A0 (en) 1989-02-27 1994-05-12 Intermediate compounds for ring-substituted 2-amino-1,2,3,4- tetrahydronaphthalenes and 3-aminochromanes
IL11471595A IL114715A0 (en) 1989-02-27 1995-07-24 Intermediate compounds for ring-substituted 2-amino - 1, 2, 3, 4-tetra-hydronaphthalenes and 3-aminochromanes

Family Applications Before (2)

Application Number Title Priority Date Filing Date
IL109647A IL109647A (en) 1989-02-27 1990-02-20 Intermediate compounds for ring-substituted 2-amino-1, 2, 3, 4-tetra- hydronaphthalenes and 3-aminochromanes
IL9346490A IL93464A (en) 1989-02-27 1990-02-20 2-Amino-1,2,3,4-Tetrahydronaplanin and 3 aminochromes with a transformed ring, a process for their preparation and pharmaceutical preparations containing them

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL10964794A IL109647A0 (en) 1989-02-27 1994-05-12 Intermediate compounds for ring-substituted 2-amino-1,2,3,4- tetrahydronaphthalenes and 3-aminochromanes
IL11471595A IL114715A0 (en) 1989-02-27 1995-07-24 Intermediate compounds for ring-substituted 2-amino - 1, 2, 3, 4-tetra-hydronaphthalenes and 3-aminochromanes

Country Status (21)

Country Link
US (1) US5637624A (pt)
EP (1) EP0385658B1 (pt)
JP (2) JP2954255B2 (pt)
KR (1) KR900012890A (pt)
CN (2) CN1031262C (pt)
AT (1) ATE116289T1 (pt)
AU (1) AU630671B2 (pt)
CA (2) CA2362972A1 (pt)
DE (1) DE69015384T2 (pt)
DK (1) DK0385658T3 (pt)
ES (1) ES2065478T3 (pt)
GR (1) GR3015136T3 (pt)
HU (2) HU209481B (pt)
IE (1) IE65769B1 (pt)
IL (5) IL109647A (pt)
MX (1) MX19637A (pt)
NZ (1) NZ232628A (pt)
PH (1) PH27444A (pt)
PT (1) PT93218B (pt)
RU (1) RU1826966C (pt)
ZA (1) ZA901277B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3837809A1 (de) * 1988-11-08 1990-05-10 Merck Patent Gmbh Tetralinderivate
DE69005625T2 (de) * 1989-04-27 1994-05-11 Upjohn Co Substituierte 3-amino-chromane.
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
CA2048846A1 (en) * 1990-08-15 1992-02-16 Craig Steven Hoechstetter Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes, 3-aminochromanes, and aminothiochromanes
ES2041211B1 (es) * 1992-02-17 1994-05-16 Uriach & Cia Sa J Procedimiento para la obtencion de nuevos dihidro y tetrahidronaftalenos.
SE9301732D0 (sv) * 1993-05-18 1993-05-18 Haakan Wilhelm Wikstroem New centrally acting 5-,6-,7-, and 8-substituted sulphone esters of n-monosubstituted 2-aminotetralins
GB9514417D0 (en) * 1995-07-14 1995-09-13 Iaf Biochem Int Novel heterocyclic compounds for the treatment of pain and use thereof
ID23503A (id) 1997-07-01 2000-04-27 Pfizer Garam-garam sertralina dan bentuk-bentuk sediaan lepas-lambat dari sertralina
FR2792529B1 (fr) * 1999-04-26 2001-09-28 Sod Conseils Rech Applic Nouvelles compositions pharmaceutiques comprenant des derives de 2-isoxazole-8-aminotetralines
WO2005037830A1 (en) * 2003-10-10 2005-04-28 Wyeth Piperidinylchromen-6-ylsulfonamide compounds as 5-hydroxytryptamine-6 ligands
MX2007007480A (es) * 2004-12-21 2007-07-20 Hoffmann La Roche Derivados de cromano y su uso como ligandos del receptor 5-ht.
BRPI0618206A2 (pt) * 2005-11-03 2011-08-23 Hoffmann La Roche arilsulfonil cromanos como inibidores de 5-ht6, bem como composição farmacêutica, uso e processo para produção dos mesmos
EP2098511A1 (en) 2008-03-07 2009-09-09 Solvias AG Process for preparing compounds containing a hydronaphtalene structure with an unsymmetrically substituted benzene ring
EP2338873A1 (en) * 2009-12-22 2011-06-29 Gmeiner, Peter New aminotetraline derivatives
KR102020441B1 (ko) * 2017-05-30 2019-09-11 주식회사 포스코 충전강관기둥 및, 강관기둥구조체

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3253037A (en) * 1962-06-19 1966-05-24 Ciba Geigy Corp N-2-alkynyl-amino-benzocylo-alkanes
GB1037014A (en) * 1963-08-02 1966-07-20 Aspro Nicholas Ltd Derivatives of 1-aminoindane
US3709996A (en) * 1963-08-02 1973-01-09 Aspro Nicholas Ltd Pharmaceutical compositions containing n-cyclopropyl-1-aminoindane compounds and adapted for administration to obtain inhibition of monoamine oxidase enzyme and process
US3637740A (en) * 1969-04-21 1972-01-25 Pfizer Aminobenzocycloalkane compounds
US3758640A (en) * 1970-07-20 1973-09-11 Hooker Chemical Corp Opolymer and a polyester polymer composition comprising vinylmonomer butadiene polymer graft c
US3929891A (en) * 1971-02-08 1975-12-30 Hoechst Ag Reduction of halonitroaromates using sulfited platinum on carbon catalysts
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
US4320148A (en) * 1980-11-24 1982-03-16 Smithkline Corporation 2-Aminotetralin compounds, pharmaceutical compositions and method of producing central alpha1 agonist activity
JPH01503777A (ja) * 1985-10-04 1989-12-21 マツジヨ‐ニ‐ウインスロツプ・ソチエタ・ペル・アチオニ 縮合脂環式アミノアルコール類
SE8605504D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel chroman derivatives
DE3719924A1 (de) * 1986-12-22 1988-06-30 Bayer Ag 8-substituierte 2-aminotetraline
CA1331191C (en) * 1988-03-25 1994-08-02 Bengt Ronny Andersson Therapeutically useful tetralin derivatives
CA2026775C (en) * 1989-01-09 1998-04-07 Per Arvid Emil Carlsson Halo substituted aminotetralins
JP2885317B2 (ja) * 1989-01-31 1999-04-19 三菱化学株式会社 耐衝撃熱可塑性樹脂組成物の製造方法

Also Published As

Publication number Publication date
CA2362972A1 (en) 1990-08-27
IL114715A0 (en) 1995-11-27
HUT65268A (en) 1994-05-02
AU5014490A (en) 1990-10-25
PT93218A (pt) 1990-08-31
AU630671B2 (en) 1992-11-05
JP3000016B2 (ja) 2000-01-17
CN1051990C (zh) 2000-05-03
US5637624A (en) 1997-06-10
HU901048D0 (en) 1990-05-28
HUT53354A (en) 1990-10-28
CN1031262C (zh) 1996-03-13
RU1826966C (ru) 1993-07-07
CN1045099A (zh) 1990-09-05
JP2954255B2 (ja) 1999-09-27
CA2010542C (en) 2002-05-14
HU9202449D0 (en) 1992-12-28
DE69015384D1 (de) 1995-02-09
IE900684L (en) 1990-08-27
ES2065478T3 (es) 1995-02-16
DE69015384T2 (de) 1995-05-18
HU221625B1 (hu) 2002-12-28
IL93464A0 (en) 1990-11-29
HU209481B (en) 1994-06-28
IE65769B1 (en) 1995-11-15
PT93218B (pt) 1996-03-29
KR900012890A (ko) 1990-09-03
CA2010542A1 (en) 1990-08-27
EP0385658B1 (en) 1994-12-28
GR3015136T3 (en) 1995-05-31
IL93464A (en) 1996-10-16
ATE116289T1 (de) 1995-01-15
IL109647A0 (en) 1994-08-26
PH27444A (en) 1993-07-02
DK0385658T3 (da) 1995-02-20
EP0385658A1 (en) 1990-09-05
CN1120532A (zh) 1996-04-17
JPH11315063A (ja) 1999-11-16
ZA901277B (en) 1991-10-30
NZ232628A (en) 1992-03-26
JPH02268151A (ja) 1990-11-01
IL109647A (en) 1997-04-15
MX19637A (es) 1994-02-28

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH1 Patent not in force