IL114629A - Intermediates for the preparation of cephalosporins - Google Patents

Intermediates for the preparation of cephalosporins

Info

Publication number
IL114629A
IL114629A IL114629A IL11462991A IL114629A IL 114629 A IL114629 A IL 114629A IL 114629 A IL114629 A IL 114629A IL 11462991 A IL11462991 A IL 11462991A IL 114629 A IL114629 A IL 114629A
Authority
IL
Israel
Prior art keywords
rnnr
rnr
hydrogen atom
rnsr
rnor
Prior art date
Application number
IL114629A
Other languages
English (en)
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of IL114629A publication Critical patent/IL114629A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL114629A 1990-06-15 1991-05-31 Intermediates for the preparation of cephalosporins IL114629A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9007491A FR2663332B1 (fr) 1990-06-15 1990-06-15 Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
IL9831891A IL98318A (en) 1990-06-15 1991-05-31 New cephalosporins, method of preparation, preparations containing them and intermediates

Publications (1)

Publication Number Publication Date
IL114629A true IL114629A (en) 1997-06-10

Family

ID=9397653

Family Applications (3)

Application Number Title Priority Date Filing Date
IL9831891A IL98318A (en) 1990-06-15 1991-05-31 New cephalosporins, method of preparation, preparations containing them and intermediates
IL114629A IL114629A (en) 1990-06-15 1991-05-31 Intermediates for the preparation of cephalosporins
IL11462995A IL114629A0 (en) 1990-06-15 1995-07-17 Intermediates for the preparation of cephalosporins

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL9831891A IL98318A (en) 1990-06-15 1991-05-31 New cephalosporins, method of preparation, preparations containing them and intermediates

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL11462995A IL114629A0 (en) 1990-06-15 1995-07-17 Intermediates for the preparation of cephalosporins

Country Status (20)

Country Link
US (1) US5416080A (hu)
EP (1) EP0462009B1 (hu)
JP (1) JP3080692B2 (hu)
KR (1) KR960009266B1 (hu)
AT (1) ATE172733T1 (hu)
CA (1) CA2044700A1 (hu)
CZ (1) CZ282244B6 (hu)
DE (1) DE69130410T2 (hu)
DK (1) DK0462009T3 (hu)
ES (1) ES2124698T3 (hu)
FR (1) FR2663332B1 (hu)
HU (1) HUT58101A (hu)
IE (1) IE912032A1 (hu)
IL (3) IL98318A (hu)
NZ (1) NZ238577A (hu)
PT (1) PT97971B (hu)
RU (1) RU2078085C1 (hu)
SK (1) SK280156B6 (hu)
UA (1) UA26431A (hu)
ZA (1) ZA914457B (hu)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5397779A (en) * 1990-06-15 1995-03-14 Roussel-Uclaf Cephalosporins
US5587372A (en) * 1991-12-12 1996-12-24 Roussel Uclaf Cephalosporins
KR0143092B1 (ko) * 1991-12-12 1998-07-15 장-끌로드 비에이으포스 7 위치에 치환된 벤질옥시이미노 라디칼을 함유하는 신규 세팔로스포린, 그의 제조 방법 및 의약으로서의 그의 용도
FR2699177A1 (fr) * 1992-12-11 1994-06-17 Roussel Uclaf Nouvelles céphalosporines comportant en position 7 un radical oxyimino substitué, leur procédé et intermédiaires de préparation et leur application comme médicaments.
EP0628562A1 (fr) * 1993-06-10 1994-12-14 Roussel Uclaf Céphalosporines comportant en position 7 un radical oxymino substitué, leurs intermédiaires, leurs procédé de préparation et leur application comme médicaments
KR100257130B1 (ko) * 1993-09-11 2000-05-15 성재갑 신규 세팔로스포린계 항생제 및 이의 제조방법
US7427680B2 (en) * 2001-01-12 2008-09-23 The Regents Of The University Of California Fluorogenic substrates for BETA-lactamase gene expression
KR0164458B1 (ko) * 1995-04-04 1999-01-15 김은영 암모니오세팔로스포린 계열 항생제 및 그의 제조방법
FR2737893B1 (fr) * 1995-08-16 1997-09-12 Roussel Uclaf Nouvelles cephalosporines comportant en position 7, un radical benzyloxyimino substitue, leur procede et intermediaires de preparation, leur application comme medicaments
US5872249A (en) * 1995-09-01 1999-02-16 Korea Institute Of Science And Technology 3-ammoniopropenyl cephalosporin compounds as antibacterial agents and process for preparing the same
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
US7214825B2 (en) * 2003-10-17 2007-05-08 Honeywell International Inc. O-(3-chloropropenyl) hydroxylamine free base
US7648998B2 (en) 2003-12-22 2010-01-19 K.U. Leuven Research & Development Imidazo 4,5-c pyridine compounds and methods of antiviral treatment
AU2005319167B2 (en) 2004-12-21 2011-09-29 Gilead Sciences, Inc. Imidazo[4,5-C]pyridine compound and method of antiviral treatment
JP3928086B2 (ja) * 2005-03-29 2007-06-13 塩野義製薬株式会社 ３−プロペニルセフェム誘導体
WO2008005519A2 (en) 2006-07-07 2008-01-10 Gilead Sciences, Inc. Novel pyridazine compound and use thereof
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound
CN114805394A (zh) * 2022-05-27 2022-07-29 山东普洛得邦医药有限公司 一种头孢克肟的合成方法
CN115260213A (zh) * 2022-05-27 2022-11-01 山东普洛得邦医药有限公司 一种头孢地尼的合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
CA1276929C (en) * 1984-04-09 1990-11-27 Masahisa Oka Cephalosporin antibacterial agents
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
DE3650157T2 (de) * 1985-12-26 1995-05-04 Eisai Co Ltd Cephalosporin-verbindungen.
GB8623211D0 (en) * 1986-09-26 1986-10-29 Glaxo Group Ltd Chemical compounds
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
FR2622585B1 (fr) * 1987-11-03 1991-04-19 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
EP0764648B1 (en) * 1988-03-16 2002-01-16 Eisai Co., Ltd. Cephem derivatives and process for the preparation thereof
US5373001A (en) * 1990-06-15 1994-12-13 Roussel Uclaf Cephalosporins

Also Published As

Publication number Publication date
DE69130410T2 (de) 1999-04-22
AU7837091A (en) 1991-12-19
DK0462009T3 (da) 1999-07-05
HU911985D0 (en) 1991-12-30
IL98318A0 (en) 1992-06-21
HUT58101A (en) 1992-01-28
IL98318A (en) 1996-01-31
ES2124698T3 (es) 1999-02-16
PT97971A (pt) 1992-03-31
IL114629A0 (en) 1995-11-27
RU2078085C1 (ru) 1997-04-27
FR2663332A1 (fr) 1991-12-20
ATE172733T1 (de) 1998-11-15
AU643289B2 (en) 1993-11-11
PT97971B (pt) 1998-11-30
IE912032A1 (en) 1991-12-18
EP0462009A1 (fr) 1991-12-18
US5416080A (en) 1995-05-16
FR2663332B1 (fr) 1997-11-07
CZ282244B6 (cs) 1997-06-11
JPH04230289A (ja) 1992-08-19
NZ238577A (en) 1992-04-28
CA2044700A1 (fr) 1991-12-16
CS183091A3 (en) 1992-10-14
KR920000766A (ko) 1992-01-29
JP3080692B2 (ja) 2000-08-28
DE69130410D1 (de) 1998-12-03
EP0462009B1 (fr) 1998-10-28
SK280156B6 (sk) 1999-09-10
UA26431A (uk) 1999-08-30
KR960009266B1 (ko) 1996-07-16
ZA914457B (en) 1992-08-26

Similar Documents

Publication Publication Date Title
IL114629A (en) Intermediates for the preparation of cephalosporins
AU1163492A (en) 3-benzylidene-1-carbamoyl-2-pyrrolidone analog
SE8004783L (sv) Delta?722-1,2,4triazolin-5-on-derivat
DK0604983T3 (da) Naphthalenderivater
AU5240493A (en) Transition metal complexes having 2,2'-bipyridine ligands substituted by at least one ammonium alkyl radical, their method of manufacture and use thereof as a redox mediator
EP1260510A4 (en) FLUORESCENT PROBES FOR THE QUANTIFICATION OF ZINC
YU49175B (sh) Postupak za dobijanje derivata bakatina iii i 10-dezacetil-bakatina iii
ZA935481B (en) Fluorinated 17 beta-substituted 4-aza-5-alpha-androstane-3-one derivatives
IL85435A (en) 2-hydroxypropoxy-benzophenone derivatives,their preparation and their use as photoinitiators
DE3163277D1 (en) Novel substituted oxonicotinates, their use as plant growth regulators and plant growth regulating compositions containing them
TW337985B (en) "N-(B-branched alkyl)-1, 2-benzisothiolin, 3ones, their preparation and their use as industrial biocides"
NO922674L (no) Spikamycinderivater og anvendelse derav
HU9503090D0 (en) Novel bisoxadiazolidine derivative
ES2103371T3 (es) Compuestos antifungicos.
DK0478194T3 (da) Bis-(2-aminocarbonylcykloalk-1-enyl)-disulfider, fremstilling og anvendelse heraf
GB1215521A (en) Organo-vanadium compounds
AU8171091A (en) Halogenoalkyl azolyl derivatives
ES8500941A1 (es) Procedimiento para preparar derivados de ciano-2-imidazopiridina
GB1519727A (en) Ectoparasiticidal agents containing diphenylcarbodiimides and ammonium salts
ES8204716A1 (es) Un procedimiento de preparacion de derivados bencilidenicos
IL85547A (en) Glycine compounds, their preparation and their use as herbicides
IE812876L (en) Ethers of substituted hydroxymethylpyrazines
ES8504139A1 (es) Procedimiento para preparar derivados de bencimidazol.
GB1455543A (en) Substituted 4,4-dicyclohexylmethane derivatives and microbicidal preparations containing them
TW333554B (en) Benzidine derivative and electrophotosensitive material using the same

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
HCE Change of name and address of proprietor(s)