IL114444A - Kit for inducing immune response against a tumor or a disease caused by an infectious agent - Google Patents
Kit for inducing immune response against a tumor or a disease caused by an infectious agentInfo
- Publication number
- IL114444A IL114444A IL11444495A IL11444495A IL114444A IL 114444 A IL114444 A IL 114444A IL 11444495 A IL11444495 A IL 11444495A IL 11444495 A IL11444495 A IL 11444495A IL 114444 A IL114444 A IL 114444A
- Authority
- IL
- Israel
- Prior art keywords
- tumor
- kit
- infectious agent
- immune response
- antibodies
- Prior art date
Links
- 239000012678 infectious agent Substances 0.000 title abstract 4
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000028993 immune response Effects 0.000 title 1
- 230000001939 inductive effect Effects 0.000 title 1
- 230000003302 anti-idiotype Effects 0.000 abstract 2
- 210000004881 tumor cell Anatomy 0.000 abstract 2
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000024932 T cell mediated immunity Effects 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000028996 humoral immune response Effects 0.000 abstract 1
- 230000003278 mimic effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
- C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
- C07K16/4266—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig against anti-tumor receptor Ig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39566—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against immunoglobulins, e.g. anti-idiotypic antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Zoology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL13246895A IL132468A (en) | 1994-07-06 | 1995-07-04 | Kit for inducing immune response against a tumor or a disease caused by an infectious agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/268,129 US5798100A (en) | 1994-07-06 | 1994-07-06 | Multi-stage cascade boosting vaccine |
Publications (2)
Publication Number | Publication Date |
---|---|
IL114444A0 IL114444A0 (en) | 1995-11-27 |
IL114444A true IL114444A (en) | 2000-02-17 |
Family
ID=23021598
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13246895A IL132468A (en) | 1994-07-06 | 1995-07-04 | Kit for inducing immune response against a tumor or a disease caused by an infectious agent |
IL11444495A IL114444A (en) | 1994-07-06 | 1995-07-04 | Kit for inducing immune response against a tumor or a disease caused by an infectious agent |
IL13246899A IL132468A0 (en) | 1994-07-06 | 1999-10-20 | A kit for inducing immune response against a tumor or a disease caused by an infection agent |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13246895A IL132468A (en) | 1994-07-06 | 1995-07-04 | Kit for inducing immune response against a tumor or a disease caused by an infectious agent |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13246899A IL132468A0 (en) | 1994-07-06 | 1999-10-20 | A kit for inducing immune response against a tumor or a disease caused by an infection agent |
Country Status (9)
Country | Link |
---|---|
US (3) | US5798100A (xx) |
EP (1) | EP0768894B1 (xx) |
JP (2) | JP3769014B2 (xx) |
AT (1) | ATE306939T1 (xx) |
AU (1) | AU2953895A (xx) |
CA (2) | CA2194166C (xx) |
DE (1) | DE69534528T2 (xx) |
IL (3) | IL132468A (xx) |
WO (1) | WO1996001126A1 (xx) |
Families Citing this family (93)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5798100A (en) * | 1994-07-06 | 1998-08-25 | Immunomedics, Inc. | Multi-stage cascade boosting vaccine |
US7354587B1 (en) * | 1994-07-06 | 2008-04-08 | Immunomedics, Inc. | Use of immunoconjugates to enhance the efficacy of multi-stage cascade boosting vaccines |
US5874540A (en) * | 1994-10-05 | 1999-02-23 | Immunomedics, Inc. | CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies |
DE69734109T2 (de) | 1996-03-20 | 2006-06-29 | Immunomedics, Inc. | Humanisierung von anti-carcinoembryonalen Antigen anti-idiotypischen Antikörper und dessen Verwendung als Tumorvakzin und zur Markierung |
IL121041A0 (en) | 1997-06-09 | 1997-11-20 | Yeda Res & Dev | Immunogenic compositions for induction of anti-tumor immunity |
EP1015035B1 (en) * | 1997-08-13 | 2009-01-28 | The Uab Research Foundation | Vaccination by topical application of genetic vectors |
US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
DE50009240D1 (de) | 1999-01-13 | 2005-02-17 | Igeneon Krebs Immuntherapie | Verwendung von Antikörpern zur Vakzinierung gegen Krebs |
US7740845B2 (en) | 2000-10-18 | 2010-06-22 | Sloan-Kettering Institute For Cancer Research | Uses of monoclonal antibody 8H9 |
US8414892B2 (en) | 2000-10-18 | 2013-04-09 | Sloan-Kettering Institute For Cancer Research | Uses of monoclonal antibody 8H9 |
US7666424B2 (en) * | 2001-10-17 | 2010-02-23 | Sloan-Kettering Institute For Cancer Research | Methods of preparing and using single chain anti-tumor antibodies |
US8501471B2 (en) | 2000-10-18 | 2013-08-06 | Sloan-Kettering Institute For Cancer Research | Uses of monoclonal antibody 8H9 |
US7737258B2 (en) * | 2000-10-18 | 2010-06-15 | Sloan-Kettering Institute For Cancer Research | Uses of monoclonal antibody 8H9 |
US7244814B2 (en) * | 2002-02-21 | 2007-07-17 | University Of Medicine & Dentistry Of New Jersey | Variant Tat proteins and methods for use thereof |
US7591994B2 (en) | 2002-12-13 | 2009-09-22 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
JP4212921B2 (ja) * | 2002-03-29 | 2009-01-21 | 独立行政法人科学技術振興機構 | 抗体を提示するタンパク質中空ナノ粒子を用いる治療薬剤およびタンパク質中空ナノ粒子 |
EP1572131B1 (en) | 2002-10-08 | 2016-07-06 | Immunomedics, Inc. | Antibody therapy |
GB0224442D0 (en) * | 2002-10-21 | 2002-11-27 | Molmed Spa | A delivery system |
HUE026914T2 (en) * | 2002-11-07 | 2016-08-29 | Immunogen Inc | Anti-CD33 antibodies and a method of treating acute myeloid leukemia |
US7696322B2 (en) * | 2003-07-28 | 2010-04-13 | Catalent Pharma Solutions, Inc. | Fusion antibodies |
KR101279748B1 (ko) | 2003-11-04 | 2013-07-04 | 가부시키가이샤 디나벡크 겐큐쇼 | 유전자 도입된 수상세포의 제조방법 |
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US9481878B2 (en) | 2004-02-13 | 2016-11-01 | Immunomedics, Inc. | Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity |
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CN103285392A (zh) | 2005-04-26 | 2013-09-11 | 卫材R&D管理株式会社 | 用于癌症免疫疗法的组合物和其用途 |
EP2674440B1 (en) | 2005-12-16 | 2019-07-03 | IBC Pharmaceuticals, Inc. | Multivalent immunoglobulin-based bioactive assemblies |
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WO2007106435A2 (en) * | 2006-03-10 | 2007-09-20 | University Of California | Cleavable vaccines compositions and methods of making and using the same |
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US9782565B2 (en) | 2008-10-01 | 2017-10-10 | Covidien Lp | Endoscopic ultrasound-guided biliary access system |
US11298113B2 (en) | 2008-10-01 | 2022-04-12 | Covidien Lp | Device for needle biopsy with integrated needle protection |
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PE20221511A1 (es) | 2019-12-13 | 2022-10-04 | Genentech Inc | Anticuerpos anti-ly6g6d y metodos de uso |
IL298402A (en) | 2020-06-19 | 2023-01-01 | Hoffmann La Roche | Antibodies that bind to CD3 and CD19 |
US20230256114A1 (en) | 2020-07-07 | 2023-08-17 | Bionecure Therapeutics, Inc. | Novel maytansinoids as adc payloads and their use for the treatment of cancer |
JPWO2022239720A1 (xx) | 2021-05-10 | 2022-11-17 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
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US4818709A (en) * | 1983-01-21 | 1989-04-04 | Primus Frederick J | CEA-family antigens, Anti-CEA antibodies and CEA immunoassay |
US5614610A (en) * | 1984-12-21 | 1997-03-25 | Oncogen | Tumor immunotherapy using anti-idiotypic antibodies |
US5525338A (en) * | 1992-08-21 | 1996-06-11 | Immunomedics, Inc. | Detection and therapy of lesions with biotin/avidin conjugates |
IL86278A (en) * | 1988-05-04 | 2003-06-24 | Yeda Res & Dev | Endowing cells with antibody specificity using chimeric t cell receptor |
ATE149841T1 (de) * | 1990-01-26 | 1997-03-15 | Immunomedics Inc | Impfstoffe gegen krebs und infektionskrankheiten |
NZ241855A (en) * | 1991-03-07 | 1994-04-27 | Gen Hospital Corp | Use of therapeutic cells to obtain cellular response to infection, tumours or autoimmune-generated cells, cells with chimaeric receptors (with binding component and destruction signal), dna encoding the receptor, vectors and antibodies to receptor |
US5932448A (en) * | 1991-11-29 | 1999-08-03 | Protein Design Labs., Inc. | Bispecific antibody heterodimers |
WO1993019163A1 (en) * | 1992-03-18 | 1993-09-30 | Yeda Research And Development Co, Ltd. | Chimeric receptor genes and cells transformed therewith |
JPH08502954A (ja) * | 1992-08-31 | 1996-04-02 | ジェナー テクノロジーズ | 抗−イディオタイプ抗体を用いた抗腫瘍t細胞応答の刺激 |
US5798100A (en) * | 1994-07-06 | 1998-08-25 | Immunomedics, Inc. | Multi-stage cascade boosting vaccine |
US5874540A (en) | 1994-10-05 | 1999-02-23 | Immunomedics, Inc. | CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies |
-
1994
- 1994-07-06 US US08/268,129 patent/US5798100A/en not_active Expired - Lifetime
-
1995
- 1995-07-04 IL IL13246895A patent/IL132468A/en not_active IP Right Cessation
- 1995-07-04 IL IL11444495A patent/IL114444A/xx not_active IP Right Cessation
- 1995-07-06 CA CA002194166A patent/CA2194166C/en not_active Expired - Fee Related
- 1995-07-06 AT AT95925387T patent/ATE306939T1/de not_active IP Right Cessation
- 1995-07-06 AU AU29538/95A patent/AU2953895A/en not_active Abandoned
- 1995-07-06 DE DE69534528T patent/DE69534528T2/de not_active Expired - Lifetime
- 1995-07-06 EP EP95925387A patent/EP0768894B1/en not_active Expired - Lifetime
- 1995-07-06 JP JP50392696A patent/JP3769014B2/ja not_active Expired - Fee Related
- 1995-07-06 WO PCT/US1995/008222 patent/WO1996001126A1/en active IP Right Grant
-
1998
- 1998-08-21 US US09/138,287 patent/US6132718A/en not_active Expired - Lifetime
-
1999
- 1999-10-20 IL IL13246899A patent/IL132468A0/xx unknown
- 1999-12-15 JP JP11355893A patent/JP2000154153A/ja active Pending
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2000
- 2000-10-16 US US09/688,089 patent/US6926893B1/en not_active Expired - Fee Related
-
2003
- 2003-11-25 CA CA002448831A patent/CA2448831A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
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JPH10503758A (ja) | 1998-04-07 |
IL132468A (en) | 2004-12-15 |
JP3769014B2 (ja) | 2006-04-19 |
US6926893B1 (en) | 2005-08-09 |
CA2194166C (en) | 2003-11-25 |
IL114444A0 (en) | 1995-11-27 |
JP2000154153A (ja) | 2000-06-06 |
IL132468A0 (en) | 2001-03-19 |
DE69534528T2 (de) | 2006-07-13 |
CA2448831A1 (en) | 2005-05-25 |
AU2953895A (en) | 1996-01-25 |
US6132718A (en) | 2000-10-17 |
US5798100A (en) | 1998-08-25 |
CA2194166A1 (en) | 1996-01-18 |
EP0768894A1 (en) | 1997-04-23 |
WO1996001126A1 (en) | 1996-01-18 |
EP0768894B1 (en) | 2005-10-19 |
ATE306939T1 (de) | 2005-11-15 |
DE69534528D1 (de) | 2006-03-02 |
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