IL112506A - Enzymatic acylation of the cephalosporin hydroxime - Google Patents

Enzymatic acylation of the cephalosporin hydroxime

Info

Publication number
IL112506A
IL112506A IL11250695A IL11250695A IL112506A IL 112506 A IL112506 A IL 112506A IL 11250695 A IL11250695 A IL 11250695A IL 11250695 A IL11250695 A IL 11250695A IL 112506 A IL112506 A IL 112506A
Authority
IL
Israel
Prior art keywords
acetate
diacetate
formula
substituted
diacetoxy butane
Prior art date
Application number
IL11250695A
Other languages
English (en)
Hebrew (he)
Other versions
IL112506A0 (en
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of IL112506A0 publication Critical patent/IL112506A0/xx
Publication of IL112506A publication Critical patent/IL112506A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/839—Bacillus subtilis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/913—Aspergillus
    • Y10S435/917—Aspergillus niger

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL11250695A 1994-02-03 1995-02-01 Enzymatic acylation of the cephalosporin hydroxime IL112506A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/191,304 US5512454A (en) 1994-02-03 1994-02-03 Enzymatic acylation of 3-hydroxymethyl cephalosporins

Publications (2)

Publication Number Publication Date
IL112506A0 IL112506A0 (en) 1995-05-26
IL112506A true IL112506A (en) 1999-03-12

Family

ID=22704949

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11250695A IL112506A (en) 1994-02-03 1995-02-01 Enzymatic acylation of the cephalosporin hydroxime

Country Status (10)

Country Link
US (1) US5512454A (de)
EP (1) EP0667396A1 (de)
JP (1) JPH07227296A (de)
KR (1) KR950032217A (de)
CN (1) CN1053447C (de)
AU (1) AU684122B2 (de)
CA (1) CA2141008A1 (de)
FI (1) FI950454A (de)
HU (1) HU217106B (de)
IL (1) IL112506A (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0801683T3 (da) * 1995-02-03 2002-06-17 Basf Ag Racematspaltning af primære og sekundære heteroatomsubstituerede aminer ved enzymkatalyseret acylering
ES2105988B1 (es) * 1996-03-15 1998-07-01 Antibioticos Sa Procedimiento para purificar 7-sustituido-amino-desacetoxi-cefalosporinas mediante el empleo de membranas de filtracion.
CA2263801A1 (en) * 1996-09-18 1998-03-26 Bristol-Myers Squibb Company Cephalosporin esterase gene from rhodosporidium toruloides
KR20010031620A (ko) * 1997-10-30 2001-04-16 스티븐 비. 데이비스 데스아세틸-세팔로스포린의 화학적 아세틸화
CN102154129B (zh) * 2011-01-10 2012-07-04 南京农业大学 一株降解棉酚的红冬孢酵母及其应用
WO2024041972A1 (en) 2022-08-23 2024-02-29 Bayer Aktiengesellschaft Nucleic acids encoding improved lipase proteins

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB966222A (en) * 1960-04-11 1964-08-06 Nat Res Dev Derivatives of cephalosporin c
CH462993A (de) * 1961-06-12 1968-09-30 Ciba Geigy Verfahren zur Herstellung von Küpenfarbstoffen
GB1080904A (en) * 1963-11-19 1967-08-31 Ciba Ltd Process for the manufacture of desacetyl-u-amino-cephalosporanic acid
US3239394A (en) * 1964-06-15 1966-03-08 Merck & Co Inc Process for producing 7-amino-cephalosporanic acid
FR1460131A (fr) * 1964-10-30 1966-06-17 Glaxo Lab Ltd Procédé de préparation de produits de dégradation de la céphalosporine c et de ses dérivés
GB1121308A (en) * 1964-10-30 1968-07-24 Glaxo Lab Ltd Cephalosporins
GB1141293A (en) * 1964-12-23 1969-01-29 Glaxo Lab Ltd Cephemoic acids and derivatives thereof
CH481142A (de) * 1966-12-05 1969-11-15 Ciba Geigy Verfahren zur Isolierung von Cephalosporin C
US3573296A (en) * 1968-07-01 1971-03-30 Bristol Myers Co Process for the preparation of 7-aminocephalosporanic acid
US3641018A (en) * 1969-06-26 1972-02-08 Lilly Co Eli Process for preparing 7-amino cephalosporanic acid
GB1355347A (en) * 1970-08-25 1974-06-05 Glaxo Lab Ltd Recovery of cephalosporin c and derivatives thereof
SU603343A3 (ru) * 1972-11-13 1978-04-15 Эли Лилли Энд Компани (Фирма) Способ очистки цефалоспорина с
US3980644A (en) * 1973-04-23 1976-09-14 Eli Lilly And Company Pentavalent phosphorus amides of cephalosporins and separation process using same
GB1474519A (de) * 1973-05-14 1977-05-25
GB1531212A (en) * 1974-11-08 1978-11-08 Glaxo Lab Ltd Enzymatic hydrolysis of 3-acyloxymethylceph-3-em-4-carboxylic acids or salts thereof
GB1565053A (en) * 1977-08-12 1980-04-16 Proter Spa Intermediate product for the preparation of cefazolin antibiotic
AT367060B (de) * 1979-01-25 1982-05-25 Biochemie Gmbh Verfahren zur herstellung neuer cephalosporinderivate
BE884385A (fr) * 1979-07-19 1981-01-19 Glaxo Group Ltd Production d'une cephalosporine par fermentation
AU540882B2 (en) * 1980-03-08 1984-12-06 Fuji Oil Company Limited Enzymatic transesterification of lipid and enzyme used therein
US4414328A (en) * 1980-07-21 1983-11-08 Fujisawa Pharmaceutical Co., Ltd. Process for the preparation of deacetylcephalosporin C
IE54838B1 (en) * 1982-04-30 1990-02-28 Unilever Plc Improvements in and relating to interesterification of triglycerides of fatty acids
US4459405A (en) * 1982-11-16 1984-07-10 Eli Lilly And Company Desacetylcephalosporin sulfones
IL70216A0 (en) * 1982-11-16 1984-02-29 Lilly Co Eli Desacetylcephalosporin sulfones
US4584371A (en) * 1984-03-01 1986-04-22 The Upjohn Company Catalytic process for preparing 3-ester-methyl cephalosporins from desacetyl-7-aminocephalosporanic acid
DE3432060A1 (de) * 1984-08-31 1986-03-06 Bayer Ag, 5090 Leverkusen Immobilisierte zellen von bacillus subtilis, immobilisierungsverfahren und verwendung des praeparats zur abspaltung der 3-acetoxygruppe aus 7-ss-acylamido-cephalosporansaeuren
US4892822A (en) * 1987-10-22 1990-01-09 General Electric Company Enzyme-catalyzed reactions involving diphenyl carbonate
DE3854042T2 (de) * 1987-12-09 1995-11-16 Kao Corp., Tokio/Tokyo Immobilisiertes Enzym und Veresterung und Zwischenveresterung mit demselben.
EP0465600B1 (de) * 1989-04-04 1995-06-07 Biopure Corporation Enzymatisches verfahren zur herstellung von 7-aminocephalosporansäure
US5229274A (en) * 1989-06-27 1993-07-20 Merck & Co., Inc. Gene encoding one step cephalosporin C amidase and expression thereof in recombinant bacillus
US5220063A (en) * 1991-05-10 1993-06-15 Hoechst Celanese Corporation Method for the preparation of arylalkanolacylamides
US5221739A (en) * 1992-01-09 1993-06-22 Eli Lilly And Company Acetylation of 3-hydroxymethyl cephalosporins
JPH06170999A (ja) * 1992-12-08 1994-06-21 Kanebo Ltd 複合発泡ポリエステルシート

Also Published As

Publication number Publication date
HU9500316D0 (en) 1995-03-28
AU684122B2 (en) 1997-12-04
IL112506A0 (en) 1995-05-26
EP0667396A1 (de) 1995-08-16
FI950454A (fi) 1995-08-04
HUT71696A (en) 1996-01-29
FI950454A0 (fi) 1995-02-02
CN1053447C (zh) 2000-06-14
HU217106B (hu) 1999-11-29
KR950032217A (ko) 1995-12-20
CN1112927A (zh) 1995-12-06
AU1158895A (en) 1995-08-10
CA2141008A1 (en) 1995-08-04
US5512454A (en) 1996-04-30
JPH07227296A (ja) 1995-08-29

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees