FI950454A0 - 3-hydroksimetyylikefalosporiinien entsymaattinen asylointi - Google Patents

3-hydroksimetyylikefalosporiinien entsymaattinen asylointi

Info

Publication number
FI950454A0
FI950454A0 FI950454A FI950454A FI950454A0 FI 950454 A0 FI950454 A0 FI 950454A0 FI 950454 A FI950454 A FI 950454A FI 950454 A FI950454 A FI 950454A FI 950454 A0 FI950454 A0 FI 950454A0
Authority
FI
Finland
Prior art keywords
enzymatic acylation
cephalosporins
hydroxymethyl
hydroxymethyl cephalosporins
acylation
Prior art date
Application number
FI950454A
Other languages
English (en)
Swedish (sv)
Other versions
FI950454A (fi
Inventor
John J Usher
Guna Romancik
Michael Politino
David A Lowe
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of FI950454A0 publication Critical patent/FI950454A0/fi
Publication of FI950454A publication Critical patent/FI950454A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/839—Bacillus subtilis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/913—Aspergillus
    • Y10S435/917—Aspergillus niger

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI950454A 1994-02-03 1995-02-02 3-hydroksimetyylikefalosporiinien entsymaattinen asylointi FI950454A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/191,304 US5512454A (en) 1994-02-03 1994-02-03 Enzymatic acylation of 3-hydroxymethyl cephalosporins

Publications (2)

Publication Number Publication Date
FI950454A0 true FI950454A0 (fi) 1995-02-02
FI950454A FI950454A (fi) 1995-08-04

Family

ID=22704949

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950454A FI950454A (fi) 1994-02-03 1995-02-02 3-hydroksimetyylikefalosporiinien entsymaattinen asylointi

Country Status (10)

Country Link
US (1) US5512454A (fi)
EP (1) EP0667396A1 (fi)
JP (1) JPH07227296A (fi)
KR (1) KR950032217A (fi)
CN (1) CN1053447C (fi)
AU (1) AU684122B2 (fi)
CA (1) CA2141008A1 (fi)
FI (1) FI950454A (fi)
HU (1) HU217106B (fi)
IL (1) IL112506A (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0801683B1 (de) * 1995-02-03 2002-05-02 Basf Aktiengesellschaft Racematspaltung primärer und sekundärer heteroatomsubstituierter amine durch enzym-katalysierte acylierung
ES2105988B1 (es) * 1996-03-15 1998-07-01 Antibioticos Sa Procedimiento para purificar 7-sustituido-amino-desacetoxi-cefalosporinas mediante el empleo de membranas de filtracion.
AU729815B2 (en) * 1996-09-18 2001-02-08 Bristol-Myers Squibb Company Cephalosporin esterase gene from Rhodosporidium toruloides
IL135827A0 (en) * 1997-10-30 2001-05-20 Bristol Myers Squibb Co Chemical acetylation of desacetyl-cephalosporins
CN102154129B (zh) * 2011-01-10 2012-07-04 南京农业大学 一株降解棉酚的红冬孢酵母及其应用
WO2024041972A1 (en) 2022-08-23 2024-02-29 Bayer Aktiengesellschaft Nucleic acids encoding improved lipase proteins

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB966222A (en) * 1960-04-11 1964-08-06 Nat Res Dev Derivatives of cephalosporin c
CH462993A (de) * 1961-06-12 1968-09-30 Ciba Geigy Verfahren zur Herstellung von Küpenfarbstoffen
GB1080904A (en) * 1963-11-19 1967-08-31 Ciba Ltd Process for the manufacture of desacetyl-u-amino-cephalosporanic acid
US3239394A (en) * 1964-06-15 1966-03-08 Merck & Co Inc Process for producing 7-amino-cephalosporanic acid
GB1121308A (en) * 1964-10-30 1968-07-24 Glaxo Lab Ltd Cephalosporins
FR1460131A (fr) * 1964-10-30 1966-06-17 Glaxo Lab Ltd Procédé de préparation de produits de dégradation de la céphalosporine c et de ses dérivés
GB1141293A (en) * 1964-12-23 1969-01-29 Glaxo Lab Ltd Cephemoic acids and derivatives thereof
CH481142A (de) * 1966-12-05 1969-11-15 Ciba Geigy Verfahren zur Isolierung von Cephalosporin C
US3573296A (en) * 1968-07-01 1971-03-30 Bristol Myers Co Process for the preparation of 7-aminocephalosporanic acid
US3641018A (en) * 1969-06-26 1972-02-08 Lilly Co Eli Process for preparing 7-amino cephalosporanic acid
GB1355347A (en) * 1970-08-25 1974-06-05 Glaxo Lab Ltd Recovery of cephalosporin c and derivatives thereof
SU603343A3 (ru) * 1972-11-13 1978-04-15 Эли Лилли Энд Компани (Фирма) Способ очистки цефалоспорина с
US3980644A (en) * 1973-04-23 1976-09-14 Eli Lilly And Company Pentavalent phosphorus amides of cephalosporins and separation process using same
GB1474519A (fi) * 1973-05-14 1977-05-25
GB1531212A (en) * 1974-11-08 1978-11-08 Glaxo Lab Ltd Enzymatic hydrolysis of 3-acyloxymethylceph-3-em-4-carboxylic acids or salts thereof
GB1565053A (en) * 1977-08-12 1980-04-16 Proter Spa Intermediate product for the preparation of cefazolin antibiotic
AT367060B (de) * 1979-01-25 1982-05-25 Biochemie Gmbh Verfahren zur herstellung neuer cephalosporinderivate
GB2060610B (en) * 1979-07-19 1983-12-07 Glaxo Group Ltd Desaacetyl cephalosporin c production
DE3163939D1 (en) * 1980-03-08 1984-07-12 Fuji Oil Co Ltd Method for enzymatic interesterification of lipid and enzyme used therein
US4414328A (en) * 1980-07-21 1983-11-08 Fujisawa Pharmaceutical Co., Ltd. Process for the preparation of deacetylcephalosporin C
IE54838B1 (en) * 1982-04-30 1990-02-28 Unilever Plc Improvements in and relating to interesterification of triglycerides of fatty acids
US4459405A (en) * 1982-11-16 1984-07-10 Eli Lilly And Company Desacetylcephalosporin sulfones
IL70216A0 (en) * 1982-11-16 1984-02-29 Lilly Co Eli Desacetylcephalosporin sulfones
US4584371A (en) * 1984-03-01 1986-04-22 The Upjohn Company Catalytic process for preparing 3-ester-methyl cephalosporins from desacetyl-7-aminocephalosporanic acid
DE3432060A1 (de) * 1984-08-31 1986-03-06 Bayer Ag, 5090 Leverkusen Immobilisierte zellen von bacillus subtilis, immobilisierungsverfahren und verwendung des praeparats zur abspaltung der 3-acetoxygruppe aus 7-ss-acylamido-cephalosporansaeuren
US4892822A (en) * 1987-10-22 1990-01-09 General Electric Company Enzyme-catalyzed reactions involving diphenyl carbonate
MY103640A (en) * 1987-12-09 1993-08-28 Kao Corp Immobilized enzyme and esterification and interesterification therewith
CA2049958A1 (en) * 1989-04-04 1990-10-05 Bing L. Wong Enzymatic production of 7-amino cephalosporanic acid
US5229274A (en) * 1989-06-27 1993-07-20 Merck & Co., Inc. Gene encoding one step cephalosporin C amidase and expression thereof in recombinant bacillus
US5220063A (en) * 1991-05-10 1993-06-15 Hoechst Celanese Corporation Method for the preparation of arylalkanolacylamides
US5221739A (en) * 1992-01-09 1993-06-22 Eli Lilly And Company Acetylation of 3-hydroxymethyl cephalosporins
JPH06170999A (ja) * 1992-12-08 1994-06-21 Kanebo Ltd 複合発泡ポリエステルシート

Also Published As

Publication number Publication date
JPH07227296A (ja) 1995-08-29
HU217106B (hu) 1999-11-29
FI950454A (fi) 1995-08-04
HUT71696A (en) 1996-01-29
CA2141008A1 (en) 1995-08-04
IL112506A0 (en) 1995-05-26
IL112506A (en) 1999-03-12
CN1112927A (zh) 1995-12-06
AU684122B2 (en) 1997-12-04
HU9500316D0 (en) 1995-03-28
US5512454A (en) 1996-04-30
CN1053447C (zh) 2000-06-14
KR950032217A (ko) 1995-12-20
EP0667396A1 (en) 1995-08-16
AU1158895A (en) 1995-08-10

Similar Documents

Publication Publication Date Title
NO20000268D0 (no) Anvendelse av Lactobacillus for reduksjon av fibrinogen nivå
FI934874A0 (fi) Stereoselektiv reducering av ketoner
NO970212D0 (no) Fremgangsmåte for fremstilling av enantiomerene av O-demetyltramadol
FI950454A0 (fi) 3-hydroksimetyylikefalosporiinien entsymaattinen asylointi
NO955258D0 (no) Medisinsk anvendelse av enzymer
FI973500A (fi) 3-pyrrolidylideeni-2-oni-kefalosporiinien johdannaiset
AU4505996A (en) 7-vinylidene cephalosporins and methods of using the same
GB2309453B (en) Surface modification of kaolinite
ITMI950383A0 (it) Procedimento enzimatico migliorato per la produzione di penicilline e cefalosporine
FI942576A0 (fi) Behandling av plasma
AU2881595A (en) Improved acylation method for penicillins and cephalosporins
FI953728A0 (fi) Parannettu menetelmä kefakloorin eristämiseksi entsymaattisen asyloinnin jälkeen
FI951329A0 (fi) Prostaglandiinin F estereitä
NO974995D0 (no) Estere av karbapenemer
FI953580A0 (fi) Asyklovirin valmistus
DE69713192T2 (de) Kombination von Enzymen
DE69733921D1 (de) Stämme der Biefhefe
AU4524196A (en) Enzymatic production of halogenated cephalosporin
NO974994D0 (no) Estere av karbapenemer
KR960022630U (ko) 용광로의 풍구
FI960180A (fi) Tiatsolijohdannaisten enantioselektiivinen valmistus
FI964057A0 (fi) Mikrofluidisering av partiklar innehaollande kalcium/oxianjoner
KR960000887U (ko) 자동차의 현가장치
ID16322A (id) Senyawa triazol produksi dan penggunaannya
ITMI941228A0 (it) Nuove cefalosporine