IL110754A - Cell compositions, their preparation and pharmaceutical compositions containing them - Google Patents

Cell compositions, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL110754A
IL110754A IL11075494A IL11075494A IL110754A IL 110754 A IL110754 A IL 110754A IL 11075494 A IL11075494 A IL 11075494A IL 11075494 A IL11075494 A IL 11075494A IL 110754 A IL110754 A IL 110754A
Authority
IL
Israel
Prior art keywords
cells
composition according
gene
pharmaceutical composition
macrophages
Prior art date
Application number
IL11075494A
Other languages
English (en)
Other versions
IL110754A0 (en
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of IL110754A0 publication Critical patent/IL110754A0/xx
Publication of IL110754A publication Critical patent/IL110754A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/57IFN-gamma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/525Tumour necrosis factor [TNF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL11075494A 1993-08-25 1994-08-23 Cell compositions, their preparation and pharmaceutical compositions containing them IL110754A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9310222A FR2709309B1 (fr) 1993-08-25 1993-08-25 Compositions cellulaires, préparation et utilisations thérapeutiques.

Publications (2)

Publication Number Publication Date
IL110754A0 IL110754A0 (en) 1994-11-11
IL110754A true IL110754A (en) 2001-04-30

Family

ID=9450378

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11075494A IL110754A (en) 1993-08-25 1994-08-23 Cell compositions, their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (1) US6210963B1 (ja)
EP (1) EP0719332B1 (ja)
JP (1) JP3731035B2 (ja)
KR (1) KR100392984B1 (ja)
AT (1) ATE272117T1 (ja)
AU (1) AU698043B2 (ja)
CA (1) CA2170159A1 (ja)
DE (1) DE69433921T2 (ja)
FI (1) FI960855A (ja)
FR (1) FR2709309B1 (ja)
IL (1) IL110754A (ja)
NO (1) NO319990B1 (ja)
WO (1) WO1995006120A1 (ja)
ZA (1) ZA946264B (ja)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6734014B1 (en) 1996-02-08 2004-05-11 The United States Of America As Represented By The Department Of Health And Human Services Methods and compositions for transforming dendritic cells and activating T cells
JP2000505650A (ja) * 1996-02-08 2000-05-16 アメリカ合衆国 樹状突起細胞を形質転換し、そしてt細胞を活性化するための方法及び組成物
FR2746109B1 (fr) 1996-03-12 1998-04-17 Rhone Poulenc Rorer Sa Milieu pour la conservation de materiel biologique
DE69732710T2 (de) * 1996-10-09 2005-07-28 Oxford Biomedica (Uk) Ltd. Mononukleare phagozyten zur verabreichung von therapeutischen arzneimitteln
US20020068048A1 (en) * 1997-09-05 2002-06-06 Patrick A. Dreyfus Method for the treatment or diagnosis of human pathologies with disseminated or difficult to access cells or tissues
JP2001517453A (ja) * 1997-09-23 2001-10-09 オックスフォード バイオメディカ(ユーケイ)リミテッド 方 法
EP1165754A1 (en) * 1999-04-06 2002-01-02 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Pharmaceutical compositions comprising circulating blood cells, preferably monocytes and uses thereof
US20020034501A1 (en) * 2000-05-18 2002-03-21 Robert Pawliuk Methods and compositions for promoting angiogenesis using monocytes
US6579522B1 (en) 2000-06-27 2003-06-17 Genvec, Inc. Replication deficient adenoviral TNF vector
CN1388248A (zh) * 2001-05-25 2003-01-01 钱其军 高效表达干扰素的肿瘤细胞内特异性增殖的腺病毒及其构建方法
AU2002341717A1 (en) * 2001-09-17 2003-04-01 Medcell Biologics, Llc. Cell therapy system
US20030086903A1 (en) 2001-11-02 2003-05-08 Genvec, Inc. Therapeutic regimen for treating cancer
AU2003203527A1 (en) * 2002-04-12 2003-10-30 Sumitomo Electric Industries, Ltd. Control of the ratio of lap to lip
MXPA05005921A (es) * 2002-12-02 2005-10-19 Abgenix Inc Anticuerpos dirigidos a factor de necrosis tumoral y sus usos.
EP1638587A4 (en) 2003-02-14 2007-04-18 Univ Missouri RECIPROCAL PROCEDURES AND COMPOSITIONS CONCERNING PROTEASOMAL INTERFERENCE
WO2005097988A1 (ja) * 2004-03-23 2005-10-20 Dnavec Research Inc. 組織の維持および/または修復に関連する骨髄関連細胞
US7838503B2 (en) * 2005-06-15 2010-11-23 Children's Medical Center Corporation Methods for extending the replicative lifespan of cells
BRPI0720342A2 (pt) * 2006-10-04 2018-09-18 Janssen Pharmaceutica N.V. preparado de células apresentadoras de antígenos artificiais e seu uso em terapias celulares.
US8202717B2 (en) 2007-01-12 2012-06-19 The Board Of Trustees Of The University Of Illinois Non-simian cells for growth of porcine reproductive and respiratory syndrome (PRRS) virus
JP5546107B2 (ja) * 2008-04-17 2014-07-09 国立大学法人宇都宮大学 RNAウイルスBmMLV陰性カイコ培養細胞株
EP2248903A1 (en) * 2009-04-29 2010-11-10 Universitat Autònoma De Barcelona Methods and reagents for efficient and targeted gene transfer to monocytes and macrophages
WO2011119920A2 (en) 2010-03-25 2011-09-29 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
EP2691530B1 (en) 2011-06-10 2018-03-07 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
AU2012216792A1 (en) 2011-09-12 2013-03-28 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies
EP2586461A1 (en) 2011-10-27 2013-05-01 Christopher L. Parks Viral particles derived from an enveloped virus
EP2679596B1 (en) 2012-06-27 2017-04-12 International Aids Vaccine Initiative HIV-1 env glycoprotein variant
AU2014255733B2 (en) 2013-04-18 2019-05-16 Tilt Biotherapeutics Oy Enhanced adoptive cell therapy
EP2848937A1 (en) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Methods of identifying novel HIV-1 immunogens
EP2873423B1 (en) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
US20170151281A1 (en) 2015-02-19 2017-06-01 Batu Biologics, Inc. Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3072901A1 (en) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
CN110709508A (zh) * 2017-03-28 2020-01-17 朱正仑 治疗新生性疾病的方法
EP3876977A1 (en) 2018-11-06 2021-09-15 The Regents Of The University Of California Chimeric antigen receptors for phagocytosis
US11026973B2 (en) 2019-04-30 2021-06-08 Myeloid Therapeutics, Inc. Engineered phagocytic receptor compositions and methods of use thereof
WO2021046243A2 (en) 2019-09-03 2021-03-11 Myeloid Therapeutics, Inc. Methods and compositions for genomic integration
US10980836B1 (en) 2019-12-11 2021-04-20 Myeloid Therapeutics, Inc. Therapeutic cell compositions and methods of manufacturing and use thereof
EP4240367A2 (en) 2020-11-04 2023-09-13 Myeloid Therapeutics, Inc. Engineered chimeric fusion protein compositions and methods of use thereof
CN114657143B (zh) * 2022-03-11 2022-10-25 西安电子科技大学 一种肿瘤微环境调控型car-单核/巨噬细胞及其制备方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989005349A1 (en) * 1987-12-09 1989-06-15 The Australian National University Method of combating viral infections
US5399493A (en) * 1989-06-15 1995-03-21 The Regents Of The University Of Michigan Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
CA1340565C (en) * 1989-06-29 1999-05-25 Thomas B. Okarma Device and process for cell capture and recovery
US5246921A (en) * 1990-06-26 1993-09-21 The Wistar Institute Of Anatomy And Biology Method for treating leukemias
FR2683725B1 (fr) * 1991-11-15 1995-07-07 Pasteur Institut Composition cellulaire pour le traitement des organismes humains ou animaux.
EP0667792A1 (en) * 1991-11-22 1995-08-23 The General Hospital Corporation Specific tolerance in transplantation
US5338165A (en) * 1991-11-25 1994-08-16 Ford Motor Company Automotive fuel pump with modular pump housing
GB9125623D0 (en) * 1991-12-02 1992-01-29 Dynal As Cell modification
US5436151A (en) * 1992-04-03 1995-07-25 Regents Of The University Of Minnesota Method for culturing human hematopoietic stem cells in vitro
DE4219626A1 (de) * 1992-06-16 1993-12-23 Wehling Peter Priv Doz Dr Med Methode zur Einschleusung therapeutisch relevanter Gene in Körperzellen
CA2158455C (en) * 1993-03-17 2003-05-27 Nicholas P. Restifo Immunogenic chimeras comprising nucleic acid sequences encoding endoplasmic reticulum signal sequence peptides and at least one other peptide and their uses in vaccines and disease treatments
US5543328A (en) * 1993-08-13 1996-08-06 Genetic Therapy, Inc. Adenoviruses having modified fiber proteins
WO1996025507A2 (en) * 1995-02-17 1996-08-22 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Methods of preparation and use of recombinant adenoviral vectors

Also Published As

Publication number Publication date
JPH09501837A (ja) 1997-02-25
EP0719332A1 (fr) 1996-07-03
NO960743L (no) 1996-03-25
WO1995006120A1 (fr) 1995-03-02
US6210963B1 (en) 2001-04-03
FI960855A0 (fi) 1996-02-23
CA2170159A1 (fr) 1995-03-02
FR2709309B1 (fr) 1995-11-10
NO319990B1 (no) 2005-10-10
FR2709309A1 (fr) 1995-03-03
IL110754A0 (en) 1994-11-11
DE69433921T2 (de) 2006-10-05
NO960743D0 (no) 1996-02-23
AU7539894A (en) 1995-03-21
ZA946264B (en) 1995-03-20
JP3731035B2 (ja) 2006-01-05
DE69433921D1 (de) 2004-09-02
EP0719332B1 (fr) 2004-07-28
AU698043B2 (en) 1998-10-22
KR100392984B1 (ko) 2004-10-20
ATE272117T1 (de) 2004-08-15
FI960855A (fi) 1996-04-23

Similar Documents

Publication Publication Date Title
US6210963B1 (en) Recombinant cells from the monocyte-macrophage cell line for gene therapy
JP7114532B2 (ja) 増強された養子細胞療法
JP4094053B2 (ja) 免疫または炎症応答の調節による抗がん遺伝子療法
RU2725799C2 (ru) Онколитические аденовирусы, кодирующие биспецифические антитела, а также способы и применения, связанные с ними
Cao et al. Lymphotactin gene-modified bone marrow dendritic cells act as more potent adjuvants for peptide delivery to induce specific antitumor immunity
AU711269B2 (en) Recombinant vectors derived from adenovirus for use in gene therapy
AU672195B2 (en) Defective recombinant adenoviruses expressing cytokines for use in antitumoral treatment
JP3952201B2 (ja) Hspを発現するオンコリティック微生物およびその使用
AU2002246625B2 (en) Helper virus-free herpes virus amplicon particles and uses thereof
Van Tendeloo et al. Gene-based cancer vaccines: an ex vivo approach
AU717218B2 (en) Medicinal combination useful for in vivo exogenic transfection and expression
Ali et al. Preclinical evaluation of “whole” cell vaccines for prophylaxis and therapy using a disabled infectious single cycle-herpes simplex virus vector to transduce cytokine genes
KR20230018378A (ko) 골수 세포 및 미세아교세포에서 치료 단백질을 특이적으로 발현하는 바이러스 벡터
Kanno et al. Experimental gene therapy against subcutaneously implanted glioma with a herpes simplex virus-defective vector expressing interferon-γ
Scholl et al. Gene therapy applications to cancer treatment
US6090378A (en) Composition comprising interleukin-2 and thymidine kinase for the treatment of tumors
AU717974B2 (en) Transduced human hematopoietic stem cells
AU729199B2 (en) Composition for use in the treatment of tumours and the immunization of humans and animals
Kramm et al. Experimental Strategies for Combined Suicide and Immune Cancer Gene Therapy: An Overview
CN115605586A (zh) 工程化溶瘤腺病毒
DEMATTEO et al. Gene transfer for the treatment of hepatobiliary neoplasms
Castro et al. Gene Therapy of Chronic Lymphocytic Leukemia
Hospers et al. Targeted immunotherapy-The use of dendritic cells in anti-tumor vaccines

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees