IL108690A - תהליך לסינתזה של גליקוסאמינוגליקאנים סינתטיים למחצה המכילים חומצה a-l- גלאקטרונית, מותמרים ברדיקאלים ניוקליופיליים בעמדה 3 - Google Patents
תהליך לסינתזה של גליקוסאמינוגליקאנים סינתטיים למחצה המכילים חומצה a-l- גלאקטרונית, מותמרים ברדיקאלים ניוקליופיליים בעמדה 3Info
- Publication number
- IL108690A IL108690A IL108690A IL10869094A IL108690A IL 108690 A IL108690 A IL 108690A IL 108690 A IL108690 A IL 108690A IL 10869094 A IL10869094 A IL 10869094A IL 108690 A IL108690 A IL 108690A
- Authority
- IL
- Israel
- Prior art keywords
- acid
- general formula
- nucleophilic
- aqueous solution
- glycosaminoglycans
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT93BO000126A IT1264102B1 (it) | 1993-03-29 | 1993-03-29 | Processo per la sintesi di glicosaminoglicani semisintetici contenenti acido alfa-l-galatturonico sostituito con radicali |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL108690A0 IL108690A0 (en) | 1994-05-30 |
| IL108690A true IL108690A (he) | 1998-02-22 |
Family
ID=11338860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL108690A IL108690A (he) | 1993-03-29 | 1994-02-17 | תהליך לסינתזה של גליקוסאמינוגליקאנים סינתטיים למחצה המכילים חומצה a-l- גלאקטרונית, מותמרים ברדיקאלים ניוקליופיליים בעמדה 3 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5410039A (he) |
| EP (1) | EP0618235B1 (he) |
| JP (1) | JP2726620B2 (he) |
| KR (1) | KR100191885B1 (he) |
| AT (1) | ATE155798T1 (he) |
| AU (1) | AU664938B2 (he) |
| CA (1) | CA2114863C (he) |
| DE (1) | DE69404353T2 (he) |
| DK (1) | DK0618235T3 (he) |
| ES (1) | ES2105382T3 (he) |
| FI (1) | FI105100B (he) |
| GR (1) | GR3024710T3 (he) |
| IL (1) | IL108690A (he) |
| IT (1) | IT1264102B1 (he) |
| NO (1) | NO305993B1 (he) |
| NZ (1) | NZ250816A (he) |
| TW (1) | TW266216B (he) |
| ZA (1) | ZA94892B (he) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6255295B1 (en) | 1996-12-23 | 2001-07-03 | Nutramax Laboratories, Inc. | Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue |
| US7259152B2 (en) | 2000-06-07 | 2007-08-21 | Alfa Wasserman, Inc. | Methods and compositions using sulodexide for the treatment of diabetic nephropathy |
| CA2435637A1 (en) | 2001-01-23 | 2002-08-01 | Massachusetts Institute Of Technology | Solid- and solution -phase synthesis of heparin and other glycosaminoglycans |
| EP2284535A1 (en) | 2002-03-11 | 2011-02-16 | Momenta Pharmaceuticals, Inc. | Low molecular weight heparins |
| US9139876B1 (en) | 2007-05-03 | 2015-09-22 | Momenta Pharmacueticals, Inc. | Method of analyzing a preparation of a low molecular weight heparin |
| CN102791742B (zh) * | 2010-01-19 | 2014-12-24 | 动量制药公司 | 评价肝素制剂 |
| US9068957B2 (en) | 2011-02-21 | 2015-06-30 | Momenta Pharmaceuticals, Inc. | Evaluating heparin preparations |
| KR102468224B1 (ko) * | 2016-03-09 | 2022-11-17 | 가부시키가이샤 도우사 고가쿠 겐큐쇼 | 설페이트기 및/또는 포스페이트기를 갖는 당의 제조방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4987223A (en) * | 1981-12-23 | 1991-01-22 | Choay S.A. | Derivatives of the uronic acid |
| IT1234508B (it) * | 1988-06-10 | 1992-05-19 | Alfa Wassermann Spa | Derivati eparinici e procedimento per la loro preparazione |
| IT1234826B (it) * | 1989-01-30 | 1992-05-29 | Alfa Wassermann Spa | Derivati eparinici e procedimento per la loro preparazione |
| IT1242604B (it) * | 1990-11-13 | 1994-05-16 | Alfa Wassermann Spa | Sali di glicosaminoglicani con esteri di aminoacidi, loro preparazione e formulazioni farmaceutiche che li contengono. |
| IT1260137B (it) * | 1992-04-17 | 1996-03-28 | Alfa Wassermann Spa | Glicosaminoglicani semisintetici a struttura eparinica od eparanica modificati nella posizione 2 dell'acido alfa-l-iduronico-2-0-solfato |
| IT1260136B (it) * | 1992-04-17 | 1996-03-28 | Alfa Wassermann Spa | Glicosaminoglicani semisintetici contenenti acido alfa-l-galatturonicosostituito con radicali nucleofili in posizione 3 |
| AU5504594A (en) * | 1993-02-08 | 1994-08-11 | Applied Sorting Technologies Pty Ltd | Metal detection in highly mineralised ground |
-
1993
- 1993-03-29 IT IT93BO000126A patent/IT1264102B1/it active IP Right Grant
-
1994
- 1994-02-03 CA CA002114863A patent/CA2114863C/en not_active Expired - Fee Related
- 1994-02-03 NZ NZ250816A patent/NZ250816A/en unknown
- 1994-02-09 ZA ZA94892A patent/ZA94892B/xx unknown
- 1994-02-10 AU AU55084/94A patent/AU664938B2/en not_active Ceased
- 1994-02-17 IL IL108690A patent/IL108690A/he not_active IP Right Cessation
- 1994-02-18 TW TW083101329A patent/TW266216B/zh active
- 1994-03-07 US US08/207,140 patent/US5410039A/en not_active Expired - Lifetime
- 1994-03-18 DK DK94104309.3T patent/DK0618235T3/da active
- 1994-03-18 DE DE69404353T patent/DE69404353T2/de not_active Expired - Fee Related
- 1994-03-18 ES ES94104309T patent/ES2105382T3/es not_active Expired - Lifetime
- 1994-03-18 AT AT94104309T patent/ATE155798T1/de not_active IP Right Cessation
- 1994-03-18 EP EP94104309A patent/EP0618235B1/en not_active Expired - Lifetime
- 1994-03-25 KR KR1019940006019A patent/KR100191885B1/ko not_active IP Right Cessation
- 1994-03-28 NO NO941129A patent/NO305993B1/no not_active IP Right Cessation
- 1994-03-28 FI FI941432A patent/FI105100B/fi not_active IP Right Cessation
- 1994-03-29 JP JP6059448A patent/JP2726620B2/ja not_active Expired - Fee Related
-
1997
- 1997-09-11 GR GR970402354T patent/GR3024710T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69404353D1 (de) | 1997-09-04 |
| JPH06322002A (ja) | 1994-11-22 |
| DK0618235T3 (da) | 1998-01-26 |
| FI941432A0 (fi) | 1994-03-28 |
| JP2726620B2 (ja) | 1998-03-11 |
| DE69404353T2 (de) | 1997-11-13 |
| NZ250816A (en) | 1996-02-27 |
| US5410039A (en) | 1995-04-25 |
| AU5508494A (en) | 1994-10-06 |
| IT1264102B1 (it) | 1996-09-10 |
| FI105100B (fi) | 2000-06-15 |
| ITBO930126A0 (it) | 1993-03-29 |
| ES2105382T3 (es) | 1997-10-16 |
| ZA94892B (en) | 1994-08-23 |
| NO305993B1 (no) | 1999-08-30 |
| ITBO930126A1 (it) | 1994-09-29 |
| CA2114863A1 (en) | 1994-09-30 |
| TW266216B (he) | 1995-12-21 |
| KR940021583A (ko) | 1994-10-19 |
| EP0618235B1 (en) | 1997-07-23 |
| GR3024710T3 (en) | 1997-12-31 |
| NO941129D0 (no) | 1994-03-28 |
| KR100191885B1 (ko) | 1999-06-15 |
| IL108690A0 (en) | 1994-05-30 |
| NO941129L (no) | 1994-09-30 |
| FI941432A (fi) | 1994-09-30 |
| AU664938B2 (en) | 1995-12-07 |
| CA2114863C (en) | 1999-07-20 |
| ATE155798T1 (de) | 1997-08-15 |
| EP0618235A1 (en) | 1994-10-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU658498B2 (en) | Semi-synthetic glycosaminoglycans with heparin or heparan structure of alpha-L-iduronic-2-sulfate acid modified in position 2 | |
| EP0565862B1 (en) | Semi-synthetic glycosaminoglycans containing alpha-L-galacturonic acid substituted with nucleophilic radicals in position 3 | |
| US5410039A (en) | Process for the synthesis of glycosaminoglycans containing α-L-galacturonic acid substituted with nucleophilic groups in position 3 | |
| EP0618234B1 (en) | Process for the synthesis of semisynthetic glycosaminoglycans with heparin or heparan structure modified in position 2 of the alpha-L-iduronic-2-0-sulfate acid | |
| Baumann et al. | Concepts for preparation of novel regioselective modified cellulose derivatives sulfated, aminated, carboxylated and acetylated for hemocompatible ultrathin coatings on biomaterials | |
| JPWO2003070960A1 (ja) | コンドロイチン又はコンドロイチン誘導体の製造法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| RH | Patent void |