IL104444A - a-ARYL-a-HYDROXY-b- IMIDAZOLINYL- PROPIONAMIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

a-ARYL-a-HYDROXY-b- IMIDAZOLINYL- PROPIONAMIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
IL104444A
IL104444A IL104444A IL10444493A IL104444A IL 104444 A IL104444 A IL 104444A IL 104444 A IL104444 A IL 104444A IL 10444493 A IL10444493 A IL 10444493A IL 104444 A IL104444 A IL 104444A
Authority
IL
Israel
Prior art keywords
alkyl
aryl
optionally substituted
propionamides
imidazolinyl
Prior art date
Application number
IL104444A
Other languages
English (en)
Other versions
IL104444A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL104444A0 publication Critical patent/IL104444A0/xx
Publication of IL104444A publication Critical patent/IL104444A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/26Radicals substituted by carbon atoms having three bonds to hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL104444A 1992-01-23 1993-01-20 a-ARYL-a-HYDROXY-b- IMIDAZOLINYL- PROPIONAMIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IL104444A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4201709A DE4201709A1 (de) 1992-01-23 1992-01-23 (alpha)-aryl-(alpha)-hydroxy-ss-imidazolinyl-propionsaeureamide

Publications (2)

Publication Number Publication Date
IL104444A0 IL104444A0 (en) 1993-05-13
IL104444A true IL104444A (en) 1997-06-10

Family

ID=6450062

Family Applications (1)

Application Number Title Priority Date Filing Date
IL104444A IL104444A (en) 1992-01-23 1993-01-20 a-ARYL-a-HYDROXY-b- IMIDAZOLINYL- PROPIONAMIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (22)

Country Link
US (1) US5334610A (ko)
EP (1) EP0552631B1 (ko)
JP (1) JPH05286942A (ko)
KR (1) KR930016401A (ko)
CN (1) CN1075714A (ko)
AT (1) ATE158576T1 (ko)
AU (1) AU650807B2 (ko)
CA (1) CA2087650A1 (ko)
CZ (1) CZ282024B6 (ko)
DE (2) DE4201709A1 (ko)
DK (1) DK0552631T3 (ko)
ES (1) ES2107562T3 (ko)
GR (1) GR3025179T3 (ko)
HU (1) HUT63394A (ko)
IL (1) IL104444A (ko)
MX (1) MX9300136A (ko)
MY (1) MY108826A (ko)
NZ (1) NZ245726A (ko)
PL (1) PL172005B1 (ko)
SK (1) SK278548B6 (ko)
TW (1) TW232011B (ko)
ZA (1) ZA93477B (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403818B1 (en) 2000-02-28 2002-06-11 Eisai Co., Ltd. Process for producing α-hydroxy-carbonyl compound
WO2003088915A2 (en) * 2002-04-18 2003-10-30 University Of Virginia Patent Foundation Novel sodium channel blockers
EP1569915A4 (en) * 2002-12-04 2007-07-11 Merck & Co Inc SPIROCYCLIC UREAS, COMPOSITIONS CONTAINING SAME, AND METHODS OF USE

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2312244A1 (fr) * 1975-05-30 1976-12-24 Scherico Ltd Nouvelles 2-imidazolines et leur utilisation comme agents hypoglycemiques
DE2614240C3 (de) * 1976-04-02 1980-03-06 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von Acylcyaniden
JPS5936885B2 (ja) * 1976-06-24 1984-09-06 第一製薬株式会社 糖尿病治療剤
US4136188A (en) * 1976-06-25 1979-01-23 Daiichi Seiyaku Co., Ltd. Treatment of diabetes with 2-substituted-1,3-diazacyclic compounds
US4226876A (en) * 1976-12-20 1980-10-07 Burroughs Wellcome Co. Arthropodicidal imidazoline derivatives
DK344489D0 (da) * 1989-07-12 1989-07-12 Novo Nordisk As Substituerede 2-imidazoliner og fremstilling og anvendelse deraf

Also Published As

Publication number Publication date
PL297491A1 (en) 1993-08-09
MY108826A (en) 1996-11-30
IL104444A0 (en) 1993-05-13
PL172005B1 (pl) 1997-07-31
DK0552631T3 (da) 1998-05-11
EP0552631A1 (de) 1993-07-28
AU3188893A (en) 1993-07-29
DE59307401D1 (de) 1997-10-30
KR930016401A (ko) 1993-08-26
MX9300136A (es) 1993-07-01
US5334610A (en) 1994-08-02
HU9300181D0 (en) 1993-04-28
HUT63394A (en) 1993-08-30
EP0552631B1 (de) 1997-09-24
CZ282024B6 (cs) 1997-04-16
AU650807B2 (en) 1994-06-30
CN1075714A (zh) 1993-09-01
TW232011B (ko) 1994-10-11
CA2087650A1 (en) 1993-07-24
ES2107562T3 (es) 1997-12-01
ATE158576T1 (de) 1997-10-15
ZA93477B (en) 1993-08-23
SK372292A3 (en) 1997-09-10
SK278548B6 (en) 1997-09-10
DE4201709A1 (de) 1993-07-29
GR3025179T3 (en) 1998-02-27
NZ245726A (en) 1996-01-26
CZ372292A3 (en) 1993-12-15
JPH05286942A (ja) 1993-11-02

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH Patent void