IL103508A - Pyrazino £1, 2-a| pyrrolo £2, 1-c| £1, 4| benzodiazepine- 2-alkanoic acid derivatives having anti-allergic and anti-asthmatic activities, their preparation, and pharmaceutical compositions containing them - Google Patents
Pyrazino £1, 2-a| pyrrolo £2, 1-c| £1, 4| benzodiazepine- 2-alkanoic acid derivatives having anti-allergic and anti-asthmatic activities, their preparation, and pharmaceutical compositions containing themInfo
- Publication number
- IL103508A IL103508A IL103508A IL10350892A IL103508A IL 103508 A IL103508 A IL 103508A IL 103508 A IL103508 A IL 103508A IL 10350892 A IL10350892 A IL 10350892A IL 103508 A IL103508 A IL 103508A
- Authority
- IL
- Israel
- Prior art keywords
- pyrazino
- benzodiazepine
- pyrrolo
- allergic
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27512591 | 1991-10-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL103508A0 IL103508A0 (en) | 1993-03-15 |
| IL103508A true IL103508A (en) | 1997-03-18 |
Family
ID=17551057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL103508A IL103508A (en) | 1991-10-23 | 1992-10-22 | Pyrazino £1, 2-a| pyrrolo £2, 1-c| £1, 4| benzodiazepine- 2-alkanoic acid derivatives having anti-allergic and anti-asthmatic activities, their preparation, and pharmaceutical compositions containing them |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5407933A (et) |
| EP (1) | EP0539164A1 (et) |
| KR (1) | KR930007950A (et) |
| CN (1) | CN1076450A (et) |
| AU (1) | AU651502B2 (et) |
| CA (1) | CA2081186A1 (et) |
| CZ (1) | CZ279797B6 (et) |
| FI (1) | FI924802A (et) |
| HU (1) | HUT67790A (et) |
| IL (1) | IL103508A (et) |
| MX (1) | MX9206151A (et) |
| NO (1) | NO924069L (et) |
| NZ (1) | NZ244876A (et) |
| TW (2) | TW317566B (et) |
| ZA (1) | ZA928146B (et) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7355042B2 (en) * | 2001-10-16 | 2008-04-08 | Hypnion, Inc. | Treatment of CNS disorders using CNS target modulators |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL179906C (nl) * | 1974-02-09 | 1986-12-01 | Akzo Nv | Werkwijze voor het bereiden van 1,2,3,4,10,14b-hexahydrodibenzo(c,f)pyrazino (1,2-a)azepine derivaten. |
| US4217452A (en) * | 1974-02-09 | 1980-08-12 | Akzona Incorporated | Synthesis for the preparation of tetracyclic compounds |
| NL189199C (nl) * | 1975-04-05 | 1993-02-01 | Akzo Nv | Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten. |
| US4316900A (en) * | 1977-10-05 | 1982-02-23 | Ciba-Geigy Corporation | Piperazinopyrrolobenzodiazepines |
| ZA784475B (en) * | 1977-10-05 | 1979-07-25 | Ciba Geigy Ag | Piperazinopyrrolobenzodiazepines |
| FR2601366B1 (fr) * | 1986-07-10 | 1988-11-25 | Andre Buzas | Derives de la benzhydryloxyethyl-piperazine, procedes d'obtention et de compositions pharmaceutiques les contenant. |
| FR2603583B1 (fr) * | 1986-09-05 | 1988-12-09 | Andre Buzas | Derives de la benzhydryloxyethyl-piperidine, procede d'obtention et compositions pharmaceutiques les contenant |
| DE3856387T2 (de) * | 1987-04-10 | 2000-05-11 | Monash University Clayton | 1,2,3,4,10,14b-HEXAHYDRODIBENZO-c,f]PYRAZINO-1,2-a]AZEPINO-DERIVATE |
| US4929618A (en) * | 1988-03-25 | 1990-05-29 | Ube Industries, Ltd. | Piperdine and piperazine derivatives, and antihistaminic pharmaceutical compositions containing the same |
| RU2048469C1 (ru) * | 1989-10-05 | 1995-11-20 | Санкио Компани Лимитед | Способ получения азетидинового производного или его фармацевтически приемлемой соли |
| JPH04211071A (ja) * | 1990-03-05 | 1992-08-03 | Hokuriku Seiyaku Co Ltd | 多環式化合物 |
-
1992
- 1992-10-20 EP EP92309579A patent/EP0539164A1/en not_active Withdrawn
- 1992-10-21 NO NO92924069A patent/NO924069L/no unknown
- 1992-10-21 ZA ZA928146A patent/ZA928146B/xx unknown
- 1992-10-22 AU AU27243/92A patent/AU651502B2/en not_active Ceased
- 1992-10-22 HU HU9203333A patent/HUT67790A/hu unknown
- 1992-10-22 CA CA002081186A patent/CA2081186A1/en not_active Abandoned
- 1992-10-22 TW TW081108421A patent/TW317566B/zh active
- 1992-10-22 IL IL103508A patent/IL103508A/xx not_active IP Right Cessation
- 1992-10-22 FI FI924802A patent/FI924802A/fi not_active Application Discontinuation
- 1992-10-22 TW TW084101513A patent/TW305844B/zh active
- 1992-10-23 KR KR1019920019606A patent/KR930007950A/ko not_active Application Discontinuation
- 1992-10-23 NZ NZ244876A patent/NZ244876A/en unknown
- 1992-10-23 CZ CS923204A patent/CZ279797B6/cs unknown
- 1992-10-23 CN CN92113396A patent/CN1076450A/zh active Pending
- 1992-10-23 MX MX9206151A patent/MX9206151A/es not_active IP Right Cessation
-
1994
- 1994-08-16 US US08/291,347 patent/US5407933A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HU9203333D0 (en) | 1992-12-28 |
| FI924802A (fi) | 1993-04-24 |
| EP0539164A1 (en) | 1993-04-28 |
| CA2081186A1 (en) | 1993-04-24 |
| TW317566B (et) | 1997-10-11 |
| AU651502B2 (en) | 1994-07-21 |
| TW305844B (et) | 1997-05-21 |
| AU2724392A (en) | 1993-04-29 |
| ZA928146B (en) | 1993-05-04 |
| NO924069L (no) | 1993-04-26 |
| CN1076450A (zh) | 1993-09-22 |
| NZ244876A (en) | 1995-07-26 |
| CZ320492A3 (en) | 1993-06-16 |
| US5407933A (en) | 1995-04-18 |
| KR930007950A (ko) | 1993-05-20 |
| FI924802A0 (fi) | 1992-10-22 |
| MX9206151A (es) | 1993-08-01 |
| CZ279797B6 (cs) | 1995-06-14 |
| NO924069D0 (no) | 1992-10-21 |
| HUT67790A (en) | 1995-04-28 |
| IL103508A0 (en) | 1993-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| RH | Patent void |