IL103508A - Pyrazino £1, 2-a| pyrrolo £2, 1-c| £1, 4| benzodiazepine- 2-alkanoic acid derivatives having anti-allergic and anti-asthmatic activities, their preparation, and pharmaceutical compositions containing them - Google Patents

Pyrazino £1, 2-a| pyrrolo £2, 1-c| £1, 4| benzodiazepine- 2-alkanoic acid derivatives having anti-allergic and anti-asthmatic activities, their preparation, and pharmaceutical compositions containing them

Info

Publication number
IL103508A
IL103508A IL103508A IL10350892A IL103508A IL 103508 A IL103508 A IL 103508A IL 103508 A IL103508 A IL 103508A IL 10350892 A IL10350892 A IL 10350892A IL 103508 A IL103508 A IL 103508A
Authority
IL
Israel
Prior art keywords
pyrazino
benzodiazepine
pyrrolo
allergic
preparation
Prior art date
Application number
IL103508A
Other languages
English (en)
Other versions
IL103508A0 (en
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of IL103508A0 publication Critical patent/IL103508A0/xx
Publication of IL103508A publication Critical patent/IL103508A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL103508A 1991-10-23 1992-10-22 Pyrazino £1, 2-a| pyrrolo £2, 1-c| £1, 4| benzodiazepine- 2-alkanoic acid derivatives having anti-allergic and anti-asthmatic activities, their preparation, and pharmaceutical compositions containing them IL103508A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP27512591 1991-10-23

Publications (2)

Publication Number Publication Date
IL103508A0 IL103508A0 (en) 1993-03-15
IL103508A true IL103508A (en) 1997-03-18

Family

ID=17551057

Family Applications (1)

Application Number Title Priority Date Filing Date
IL103508A IL103508A (en) 1991-10-23 1992-10-22 Pyrazino £1, 2-a| pyrrolo £2, 1-c| £1, 4| benzodiazepine- 2-alkanoic acid derivatives having anti-allergic and anti-asthmatic activities, their preparation, and pharmaceutical compositions containing them

Country Status (15)

Country Link
US (1) US5407933A (xx)
EP (1) EP0539164A1 (xx)
KR (1) KR930007950A (xx)
CN (1) CN1076450A (xx)
AU (1) AU651502B2 (xx)
CA (1) CA2081186A1 (xx)
CZ (1) CZ279797B6 (xx)
FI (1) FI924802A (xx)
HU (1) HUT67790A (xx)
IL (1) IL103508A (xx)
MX (1) MX9206151A (xx)
NO (1) NO924069L (xx)
NZ (1) NZ244876A (xx)
TW (2) TW305844B (xx)
ZA (1) ZA928146B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7355042B2 (en) * 2001-10-16 2008-04-08 Hypnion, Inc. Treatment of CNS disorders using CNS target modulators

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL179906C (nl) * 1974-02-09 1986-12-01 Akzo Nv Werkwijze voor het bereiden van 1,2,3,4,10,14b-hexahydrodibenzo(c,f)pyrazino (1,2-a)azepine derivaten.
US4217452A (en) * 1974-02-09 1980-08-12 Akzona Incorporated Synthesis for the preparation of tetracyclic compounds
NL189199C (nl) * 1975-04-05 1993-02-01 Akzo Nv Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten.
ZA784475B (en) * 1977-10-05 1979-07-25 Ciba Geigy Ag Piperazinopyrrolobenzodiazepines
US4316900A (en) * 1977-10-05 1982-02-23 Ciba-Geigy Corporation Piperazinopyrrolobenzodiazepines
FR2601366B1 (fr) * 1986-07-10 1988-11-25 Andre Buzas Derives de la benzhydryloxyethyl-piperazine, procedes d'obtention et de compositions pharmaceutiques les contenant.
FR2603583B1 (fr) * 1986-09-05 1988-12-09 Andre Buzas Derives de la benzhydryloxyethyl-piperidine, procede d'obtention et compositions pharmaceutiques les contenant
EP0379483B1 (en) * 1987-04-10 1999-12-29 Monash University 1,2,3,4,10,14b-HEXAHYDRODIBENZO c,f]PYRAZINO- 1,2-a]AZEPINO DERIVATIVES
US4929618A (en) * 1988-03-25 1990-05-29 Ube Industries, Ltd. Piperdine and piperazine derivatives, and antihistaminic pharmaceutical compositions containing the same
CA2026925A1 (en) * 1989-10-05 1991-04-06 Hiroshi Fukumi Tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use
JPH04211071A (ja) * 1990-03-05 1992-08-03 Hokuriku Seiyaku Co Ltd 多環式化合物

Also Published As

Publication number Publication date
AU2724392A (en) 1993-04-29
NO924069D0 (no) 1992-10-21
HUT67790A (en) 1995-04-28
KR930007950A (ko) 1993-05-20
MX9206151A (es) 1993-08-01
NZ244876A (en) 1995-07-26
AU651502B2 (en) 1994-07-21
EP0539164A1 (en) 1993-04-28
US5407933A (en) 1995-04-18
CA2081186A1 (en) 1993-04-24
ZA928146B (en) 1993-05-04
IL103508A0 (en) 1993-03-15
CZ279797B6 (cs) 1995-06-14
FI924802A0 (fi) 1992-10-22
CN1076450A (zh) 1993-09-22
FI924802A (fi) 1993-04-24
TW317566B (xx) 1997-10-11
CZ320492A3 (en) 1993-06-16
HU9203333D0 (en) 1992-12-28
TW305844B (xx) 1997-05-21
NO924069L (no) 1993-04-26

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Legal Events

Date Code Title Description
FF Patent granted
RH Patent void