IL103448A - Salts of the base 4-amidino- 1-indanone-2(- amidinohydrazone, pharmaceutical compositions containing them and their preparation - Google Patents

Salts of the base 4-amidino- 1-indanone-2(- amidinohydrazone, pharmaceutical compositions containing them and their preparation

Info

Publication number
IL103448A
IL103448A IL103448A IL10344892A IL103448A IL 103448 A IL103448 A IL 103448A IL 103448 A IL103448 A IL 103448A IL 10344892 A IL10344892 A IL 10344892A IL 103448 A IL103448 A IL 103448A
Authority
IL
Israel
Prior art keywords
acid
acids
formula
unsubstituted
indanone
Prior art date
Application number
IL103448A
Other languages
English (en)
Other versions
IL103448A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL103448A0 publication Critical patent/IL103448A0/xx
Publication of IL103448A publication Critical patent/IL103448A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/18—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/16—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of hydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/06—One of the condensed rings being a six-membered aromatic ring the other ring being four-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Cereal-Derived Products (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL103448A 1991-10-16 1992-10-15 Salts of the base 4-amidino- 1-indanone-2(- amidinohydrazone, pharmaceutical compositions containing them and their preparation IL103448A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH304191 1991-10-16

Publications (2)

Publication Number Publication Date
IL103448A0 IL103448A0 (en) 1993-03-15
IL103448A true IL103448A (en) 1998-01-04

Family

ID=4247296

Family Applications (1)

Application Number Title Priority Date Filing Date
IL103448A IL103448A (en) 1991-10-16 1992-10-15 Salts of the base 4-amidino- 1-indanone-2(- amidinohydrazone, pharmaceutical compositions containing them and their preparation

Country Status (24)

Country Link
EP (1) EP0538193B1 (cs)
JP (1) JP2788579B2 (cs)
KR (1) KR100265307B1 (cs)
AT (1) ATE145896T1 (cs)
AU (1) AU658931B2 (cs)
CA (1) CA2080545C (cs)
CY (1) CY2127B1 (cs)
CZ (1) CZ279601B6 (cs)
DE (1) DE59207617D1 (cs)
DK (1) DK0538193T3 (cs)
ES (1) ES2095444T3 (cs)
FI (1) FI112212B (cs)
GR (1) GR3021903T3 (cs)
HK (1) HK1005023A1 (cs)
HU (1) HU226954B1 (cs)
IL (1) IL103448A (cs)
MX (1) MX9205934A (cs)
NO (1) NO178108C (cs)
NZ (1) NZ244725A (cs)
RU (1) RU2081108C1 (cs)
SA (1) SA93130417B1 (cs)
SG (1) SG43185A1 (cs)
SK (1) SK279938B6 (cs)
ZA (1) ZA927957B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2103166B1 (es) * 1992-08-26 1998-04-01 Ciba Geigy Ag Procedimiento para la obtencion de amidinohidrazonas biciclicas.
WO1996017930A1 (fr) * 1994-12-09 1996-06-13 Ajinomoto Co., Inc. Nouveau gene de decarboxylase de lysine et procede de production de lysine l
EP0808309B1 (en) * 1995-01-26 2004-10-06 Novartis AG Imidazole derivatives, their preparation and their use as s-adenosylmethionine decarboxylase (=samdc) inhibitors
JP2005519110A (ja) * 2002-03-04 2005-06-30 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト 新規なケイ皮酸塩、その調製方法及び医薬品としての使用
GT200600316A (es) * 2005-07-20 2007-04-02 Sales de 4-metilo-n-(3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo)-3-(4-piridina-3-ilo-pirimidina-2-iloamino)- benzamida.
EP1884515A1 (en) 2006-07-31 2008-02-06 Laboratorios del Dr. Esteve S.A. Substituted indanyl sulfonamide compounds, their preparation and use as medicaments

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU645799B2 (en) * 1990-05-07 1994-01-27 Novartis Ag Hydrazones

Also Published As

Publication number Publication date
FI924650A7 (fi) 1993-04-17
HU9203234D0 (en) 1992-12-28
IL103448A0 (en) 1993-03-15
SG43185A1 (en) 1997-10-17
CZ279601B6 (cs) 1995-05-17
CA2080545A1 (en) 1993-04-17
NO924001L (no) 1993-04-19
SA93130417B1 (ar) 2005-11-12
NO178108C (no) 1996-01-24
FI112212B (fi) 2003-11-14
ES2095444T3 (es) 1997-02-16
JP2788579B2 (ja) 1998-08-20
ATE145896T1 (de) 1996-12-15
JPH05239011A (ja) 1993-09-17
SK315292A3 (en) 1995-04-12
RU2081108C1 (ru) 1997-06-10
KR930007896A (ko) 1993-05-20
GR3021903T3 (en) 1997-03-31
EP0538193B1 (de) 1996-12-04
FI924650A0 (fi) 1992-10-14
NO178108B (no) 1995-10-16
CA2080545C (en) 2005-11-29
NO924001D0 (no) 1992-10-15
EP0538193A3 (en) 1993-06-16
AU2704092A (en) 1993-04-22
EP0538193A2 (de) 1993-04-21
CY2127B1 (en) 2002-06-21
HK1005023A1 (en) 1998-12-18
DK0538193T3 (da) 1996-12-23
NZ244725A (en) 1995-05-26
SK279938B6 (sk) 1999-06-11
KR100265307B1 (ko) 2000-09-15
MX9205934A (es) 1993-04-01
ZA927957B (en) 1993-04-26
AU658931B2 (en) 1995-05-04
HU226954B1 (en) 2010-03-29
HUT63149A (en) 1993-07-28
DE59207617D1 (de) 1997-01-16
CZ315292A3 (en) 1993-05-12

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Legal Events

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MM9K Patent not in force due to non-payment of renewal fees