IL103005A - Process for the manufacture of pharmaceutical preparations containing 2- (4-isobutylphenyl) propionic acid - Google Patents

Process for the manufacture of pharmaceutical preparations containing 2- (4-isobutylphenyl) propionic acid

Info

Publication number
IL103005A
IL103005A IL10300592A IL10300592A IL103005A IL 103005 A IL103005 A IL 103005A IL 10300592 A IL10300592 A IL 10300592A IL 10300592 A IL10300592 A IL 10300592A IL 103005 A IL103005 A IL 103005A
Authority
IL
Israel
Prior art keywords
weight
propionic acid
isobutylphenyl
agglomerates
starch
Prior art date
Application number
IL10300592A
Other languages
English (en)
Hebrew (he)
Other versions
IL103005A0 (en
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of IL103005A0 publication Critical patent/IL103005A0/xx
Publication of IL103005A publication Critical patent/IL103005A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL10300592A 1991-09-06 1992-08-31 Process for the manufacture of pharmaceutical preparations containing 2- (4-isobutylphenyl) propionic acid IL103005A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919119052A GB9119052D0 (en) 1991-09-06 1991-09-06 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
IL103005A0 IL103005A0 (en) 1993-01-31
IL103005A true IL103005A (en) 1996-01-19

Family

ID=10700981

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10300592A IL103005A (en) 1991-09-06 1992-08-31 Process for the manufacture of pharmaceutical preparations containing 2- (4-isobutylphenyl) propionic acid

Country Status (16)

Country Link
US (1) US5512302A (de)
EP (1) EP0602112B1 (de)
JP (1) JP3444597B2 (de)
KR (1) KR100253046B1 (de)
AT (1) ATE353213T1 (de)
AU (1) AU655673B2 (de)
CA (1) CA2116956C (de)
CZ (1) CZ282271B6 (de)
DE (1) DE69233678T2 (de)
FI (1) FI107878B (de)
GB (1) GB9119052D0 (de)
IL (1) IL103005A (de)
IN (1) IN174169B (de)
RU (1) RU2123841C1 (de)
WO (1) WO1993004676A1 (de)
ZA (1) ZA926709B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI101039B (fi) * 1992-10-09 1998-04-15 Eeva Kristoffersson Menetelmä lääkepellettien valmistamiseksi
HUP0104606A3 (en) * 1998-12-18 2003-01-28 Basf Ag A pharmaceutical mixture comprising a profen
US6726929B1 (en) 1998-12-18 2004-04-27 Basf Aktiengesellschaft Pharmaceutical mixture comprising a profen
US6251945B1 (en) * 1999-01-14 2001-06-26 Knoll Aktiengesellschaft Pharmaceutical mixture comprising a combination of a profen and other active compounds
DE10003757A1 (de) 2000-01-28 2001-08-02 Knoll Ag Ibuprofen-Wirkstoffzubereitung
US20040173147A1 (en) * 2001-06-07 2004-09-09 Figueroa Iddys D. Application of a bioactive agent to a delivery substrate
US20040173146A1 (en) * 2001-06-07 2004-09-09 Figueroa Iddys D. Application of a bioactive agent to a delivery substrate
US6962715B2 (en) * 2001-10-24 2005-11-08 Hewlett-Packard Development Company, L.P. Method and dosage form for dispensing a bioactive substance
DE10153934A1 (de) * 2001-11-06 2003-05-22 Basf Ag Verfahren zur Kristallisation von Profenen
US20050203482A1 (en) * 2004-03-15 2005-09-15 Chinea Vanessa I. Pharmaceutical dispensing apparatus and method
US20050202051A1 (en) * 2004-03-15 2005-09-15 Chinea Vanessa I. Pharmaceutical vehicle
JP2008266270A (ja) * 2007-04-25 2008-11-06 Kowa Co イブプロフェン、トラネキサム酸及び糖アルコールを含有する固形製剤

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE92752T1 (de) * 1987-07-08 1993-08-15 American Home Prod Spruehgetrocknete ibuprofen-zusammensetzungen.
US5240712A (en) * 1987-07-17 1993-08-31 The Boots Company Plc Therapeutic agents
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
US4911921A (en) * 1989-02-02 1990-03-27 Mallinckrodt, Inc. High ibuprofen content granulations
US5266723A (en) * 1989-05-16 1993-11-30 Medice, Ltd., Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg Process for the preparation of optically active 2-aryl-alkanoic acids, especially 2-aryl-propionic acids
US5087454A (en) * 1990-07-30 1992-02-11 American Home Products Corporation Ibuprofen tablet
US5260337A (en) * 1992-07-29 1993-11-09 Merck & Co., Inc. Ibuprofen-muscle relaxant combinations
US5332834A (en) * 1992-12-02 1994-07-26 Hoechst Celanese Corporation Racemization of an enantomerically enriched α-aryl carboxylic acid

Also Published As

Publication number Publication date
CZ49994A3 (en) 1994-07-13
JPH06510532A (ja) 1994-11-24
US5512302A (en) 1996-04-30
AU655673B2 (en) 1995-01-05
RU2123841C1 (ru) 1998-12-27
CA2116956A1 (en) 1993-03-18
FI941046A (fi) 1994-03-04
CZ282271B6 (cs) 1997-06-11
FI941046A0 (fi) 1994-03-04
DE69233678D1 (de) 2007-03-22
KR100253046B1 (ko) 2000-05-01
IL103005A0 (en) 1993-01-31
JP3444597B2 (ja) 2003-09-08
DE69233678T2 (de) 2008-01-24
ZA926709B (en) 1993-04-28
ATE353213T1 (de) 2007-02-15
EP0602112A1 (de) 1994-06-22
EP0602112B1 (de) 2007-02-07
AU2487092A (en) 1993-04-05
IN174169B (de) 1994-10-01
WO1993004676A1 (en) 1993-03-18
FI107878B (fi) 2001-10-31
CA2116956C (en) 2002-07-16
GB9119052D0 (en) 1991-10-23

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH Patent void
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees