IL102792A - Cyclic urea compositions and pharmaceutical compositions containing them - Google Patents

Cyclic urea compositions and pharmaceutical compositions containing them

Info

Publication number
IL102792A
IL102792A IL10279292A IL10279292A IL102792A IL 102792 A IL102792 A IL 102792A IL 10279292 A IL10279292 A IL 10279292A IL 10279292 A IL10279292 A IL 10279292A IL 102792 A IL102792 A IL 102792A
Authority
IL
Israel
Prior art keywords
nil
unsubstituted
saturated
substituted
unsaturated
Prior art date
Application number
IL10279292A
Other languages
English (en)
Other versions
IL102792A0 (en
Original Assignee
Procter & Gamble Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble Pharma filed Critical Procter & Gamble Pharma
Publication of IL102792A0 publication Critical patent/IL102792A0/xx
Publication of IL102792A publication Critical patent/IL102792A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL10279292A 1991-08-14 1992-08-12 Cyclic urea compositions and pharmaceutical compositions containing them IL102792A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74486491A 1991-08-14 1991-08-14

Publications (2)

Publication Number Publication Date
IL102792A0 IL102792A0 (en) 1993-01-31
IL102792A true IL102792A (en) 1997-01-10

Family

ID=24994265

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10279292A IL102792A (en) 1991-08-14 1992-08-12 Cyclic urea compositions and pharmaceutical compositions containing them

Country Status (24)

Country Link
US (1) US5691369A (xx)
EP (2) EP0891976B1 (xx)
JP (1) JPH06509803A (xx)
AT (2) ATE226202T1 (xx)
AU (1) AU665209B2 (xx)
BR (1) BR9206371A (xx)
CA (1) CA2115426C (xx)
CZ (1) CZ286265B6 (xx)
DE (2) DE69228751T2 (xx)
DK (1) DK0598046T3 (xx)
ES (1) ES2132127T3 (xx)
FI (1) FI940656A (xx)
GR (1) GR3030579T3 (xx)
HU (1) HUT70029A (xx)
IL (1) IL102792A (xx)
MX (1) MX9204735A (xx)
MY (1) MY109528A (xx)
NO (1) NO305285B1 (xx)
NZ (1) NZ243937A (xx)
PL (1) PL170960B1 (xx)
PT (1) PT100776B (xx)
RU (1) RU2142461C1 (xx)
SK (1) SK279677B6 (xx)
WO (1) WO1993004060A1 (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3040473B2 (ja) * 1991-08-14 2000-05-15 プロクター、エンド、ギャンブル、ファーマスーティカルズ、インコーポレーテッド 抗不整脈及び抗細動剤として有用な新規4−オキソ環式尿素類
US6083945A (en) * 1995-06-07 2000-07-04 The Procter & Gamble Company Cyclic ureas useful as antiarrhythmic and antifibrillatory agents
KR100381213B1 (ko) * 1998-03-26 2003-08-14 주식회사 엘지생명과학 파네실전이효소억제능을갖는사이클릭우레아유도체및그의제조방법
US6607749B1 (en) * 1998-09-08 2003-08-19 Smithkline Beecham Corporation Lipstatin derivative-soluble fiber tablets
US6288151B1 (en) * 1999-10-14 2001-09-11 Air Products And Chemicals, Inc. Alkylated aminoalkyl cyclic urea surfactants
US7129359B2 (en) 2002-07-09 2006-10-31 National Health Research Institutes Imidazolidinone compounds
US7259174B2 (en) 2004-05-25 2007-08-21 National Health Research Institutes Imidazolidinone compounds

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2776979A (en) * 1956-04-05 1957-01-08 Norwich Pharma Co 1-nitroso-2-imidazolidone and process
NL257071A (xx) * 1959-10-23
US3254075A (en) * 1963-08-28 1966-05-31 Norwich Pharma Co 1-(2-hydroxyethyl and 2-haloethyl-3-(5-nitrofurfurylideneamino)-2-imidazolidinones
US3415821A (en) * 1965-09-07 1968-12-10 Norwich Pharma Co 1-(5-substituted)furfurylideneamino hydantoins and imidazolidinones
US3407195A (en) * 1967-04-03 1968-10-22 Norwich Pharma Co 4-methyl-1-(5-nitrofurfurylideneamino)-2-imidazolidinone
DE2335144A1 (de) * 1973-07-07 1975-01-23 Schering Ag Basisch substituierte nitroimidazolmethylenamino-imidazolidinone
US4775670A (en) * 1980-09-29 1988-10-04 E. R. Squibb & Sons, Inc. 2-oxo-1-azetidinesulfonic acid salts
US4393204A (en) * 1982-05-21 1983-07-12 Norwich Eaton Pharmaceuticals, Inc. 3-[[5-(4-Chlorophenyl)furfurylidene]amino]-5-(substituted)-2-oxazolidinones
US4543359A (en) * 1982-10-01 1985-09-24 Eaton Laboratories, Inc. Treating cardiac arrhythmias with dantrolene sodium
US4705799A (en) * 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
US4581370A (en) * 1983-07-12 1986-04-08 Schering A.G. Antiarrhythmic imidazoliums
US4720580A (en) * 1984-09-21 1988-01-19 American Home Products Corporation N-(aminoalkylene)benzenesulfonamides
US4707499A (en) * 1985-12-02 1987-11-17 G. D. Searle & Co. 3-alkyl-5-(substituted amino)methyl)dihydro-3-phenyl-2(3H)-furanones and imino analogs thereof used for treatment of arrhythmia
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof
US4783443A (en) * 1986-03-03 1988-11-08 The University Of Chicago Amino acyl cephalosporin derivatives
US4713832A (en) * 1986-04-11 1987-12-15 Ampex Corporation Programmable divider up/down counter with anti-aliasing feature and asynchronous read/write
US4870095A (en) * 1988-06-13 1989-09-26 Sterling Drug, Inc. 1H-pyrazole-1-alkanamides, antiarrhythmic compositions and use
EP0347733A1 (en) * 1988-06-20 1989-12-27 Eisai Co., Ltd. Optically active hydantoin derivatives
US5137905A (en) * 1988-10-27 1992-08-11 The Upjohn Company Heterocyclic acetylenic amines having central nervous system activity
US4966967A (en) * 1989-09-15 1990-10-30 Berlex Laboratories, Inc. 3,4,5,6-tetrahydro-2H-1,7,4-benzodioxazonines as cardiovascular agents
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
US4963561A (en) * 1990-02-28 1990-10-16 Sterling Drug Inc. Imidazopyridines, their preparation and use
FR2678272B1 (fr) * 1991-06-27 1994-01-14 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
BR9206353A (pt) * 1991-08-14 1995-11-07 Procter & Gamble Pharma Uretanos cíclicos utilizáveis como agentes antiarrítmicos e antifibrilatórios

Also Published As

Publication number Publication date
RU2142461C1 (ru) 1999-12-10
DE69228751D1 (de) 1999-04-29
SK17094A3 (en) 1995-02-08
NO305285B1 (no) 1999-05-03
MX9204735A (es) 1994-03-31
JPH06509803A (ja) 1994-11-02
BR9206371A (pt) 1995-10-17
US5691369A (en) 1997-11-25
CA2115426A1 (en) 1993-03-04
HUT70029A (en) 1995-09-28
DE69232825D1 (de) 2002-11-21
GR3030579T3 (en) 1999-10-29
CZ30594A3 (en) 1994-12-15
NO940498L (no) 1994-02-14
NO940498D0 (no) 1994-02-14
EP0891976A1 (en) 1999-01-20
FI940656A0 (fi) 1994-02-11
EP0598046A1 (en) 1994-05-25
FI940656A (fi) 1994-02-11
AU2460092A (en) 1993-03-16
MY109528A (en) 1997-02-28
CA2115426C (en) 2001-09-11
HU9400391D0 (en) 1994-05-30
ATE226202T1 (de) 2002-11-15
PT100776A (pt) 1993-12-31
WO1993004060A1 (en) 1993-03-04
EP0891976B1 (en) 2002-10-16
EP0598046B1 (en) 1999-03-24
AU665209B2 (en) 1995-12-21
NZ243937A (en) 1996-10-28
ATE178063T1 (de) 1999-04-15
PL170960B1 (pl) 1997-02-28
DK0598046T3 (da) 1999-05-25
CZ286265B6 (cs) 2000-03-15
PT100776B (pt) 1999-07-30
IL102792A0 (en) 1993-01-31
ES2132127T3 (es) 1999-08-16
SK279677B6 (sk) 1999-02-11
DE69228751T2 (de) 1999-10-07

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees