IL102355A0 - N-phenylthiourea derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

N-phenylthiourea derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL102355A0
IL102355A0 IL102355A IL10235592A IL102355A0 IL 102355 A0 IL102355 A0 IL 102355A0 IL 102355 A IL102355 A IL 102355A IL 10235592 A IL10235592 A IL 10235592A IL 102355 A0 IL102355 A0 IL 102355A0
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
preparation
compositions containing
compounds
subgroup
Prior art date
Application number
IL102355A
Other languages
English (en)
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL102355A0 publication Critical patent/IL102355A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)
IL102355A 1991-07-01 1992-06-29 N-phenylthiourea derivatives,their preparation and pharmaceutical compositions containing them IL102355A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72400191A 1991-07-01 1991-07-01

Publications (1)

Publication Number Publication Date
IL102355A0 true IL102355A0 (en) 1993-01-14

Family

ID=24908548

Family Applications (1)

Application Number Title Priority Date Filing Date
IL102355A IL102355A0 (en) 1991-07-01 1992-06-29 N-phenylthiourea derivatives,their preparation and pharmaceutical compositions containing them

Country Status (24)

Country Link
EP (1) EP0528146B1 (ja)
JP (1) JPH05221959A (ja)
KR (1) KR930002311A (ja)
AT (1) ATE134364T1 (ja)
AU (1) AU657141B2 (ja)
CA (1) CA2072704A1 (ja)
CZ (1) CZ204692A3 (ja)
DE (1) DE69208408T2 (ja)
DK (1) DK0528146T3 (ja)
ES (1) ES2083625T3 (ja)
FI (1) FI923033A (ja)
GR (1) GR3019785T3 (ja)
HK (1) HK73196A (ja)
HU (1) HUT62558A (ja)
IE (1) IE73488B1 (ja)
IL (1) IL102355A0 (ja)
MX (1) MX9203838A (ja)
NO (1) NO922564L (ja)
NZ (1) NZ243352A (ja)
RO (1) RO111933B1 (ja)
RU (1) RU2087467C1 (ja)
SK (1) SK204692A3 (ja)
TW (1) TW213448B (ja)
ZA (1) ZA924823B (ja)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0938480A1 (en) * 1996-11-14 1999-09-01 American Home Products Corporation Substituted tetrahydro-1,3,5-triazin-2 1h]-thiones as anti-atherosclerotic agents
AU5731098A (en) * 1997-02-03 1998-08-25 American Home Products Corporation 2-substituted-1-acyl-1,2-dihydroquinoline derivatives to increase hdl-cholesterol level
WO1998057926A1 (en) * 1997-06-16 1998-12-23 American Home Products Corporation Elevation of hdl cholesterol by n-[2-[ (aminothioxomethyl)hydrazono] -2-arylethyl]amides
US6011053A (en) * 1997-08-01 2000-01-04 American Home Products Corporation Substituted indole-1-carbothioic acid amides as novel antiatherosclerotic agents
TW415942B (en) * 1997-09-03 2000-12-21 American Home Prod Novel substituted 1-aryl-3-heteroaryl-thioureas and substituted 1-aryl-3-heteroaryl-isothioureas as antiatherosclerotic agents
US6455566B1 (en) 1997-09-03 2002-09-24 Wyeth Substituted 1-aryl-3-heteroaryl-thioureas (or isothioureas) as antiatherosclerotic agents
WO1999011621A2 (en) * 1997-09-03 1999-03-11 American Home Products Corporation Thiourea for increasing hdl-cholesterol levels, which are useful as anti-atherosclerotic agents
AU9125998A (en) * 1997-09-03 1999-03-22 American Home Products Corporation Substituted indole-1-carbothioic acid amides as novel antiatherosclerotic agents
DE10017881A1 (de) * 2000-04-11 2001-10-25 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
WO2003024441A1 (fr) 2001-09-14 2003-03-27 Shionogi & Co., Ltd. Nouvelle utilisation de composes tricycliques
EP1303483B1 (en) * 2000-08-21 2008-04-23 Pacific Corporation Novel thiourea derivatives and the pharmaceutical compositions containing the same
DE60120421T2 (de) 2000-08-21 2006-12-28 Pacific Corp. Neue (thio)harnstoffverbindungen und arzneimittelkompositionen, die diese enthalten
US6472430B2 (en) 2000-10-02 2002-10-29 Hassan M. Elokdah Amino thioxomethyl amino oxyacetic acid derivatives
US8124625B2 (en) 2001-09-14 2012-02-28 Shionogi & Co., Ltd. Method of enhancing the expression of apolipoprotein AI using olefin derivatives
US7429593B2 (en) 2001-09-14 2008-09-30 Shionogi & Co., Ltd. Utilities of amide compounds
ES2362770B1 (es) * 2009-12-24 2012-05-22 Universidad De Sevilla Uso de compuesto n-fenil-n'-(3-metil-2-butenil)tiourea para la elaboración de medicamentos destinados al tratamiento de la encefalopatía hepática.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950537A (en) * 1973-06-29 1976-04-13 Rohm And Haas Company Gastrointestinally active thioureas
IL67417A (en) * 1982-01-26 1989-10-31 American Cyanamid Co Antiatherosclerotic substituted ureas,process for their preparation and pharmaceutical compositions containing them
ES2037768T3 (es) * 1987-07-02 1993-07-01 Warner-Lambert Company Procedimiento para preparar n-(fenil(2,6-disustituido))-ureas y carbamatos inhibidores de acil-coa: colesterol acil-transferasa.
US5116848A (en) * 1988-03-30 1992-05-26 Warner-Lambert Company N-(((2,6-disubstituted)phenyl)-n-diarylalkyl)ureas as antihyperlipidemic and antiatherosclerotic agents
GB8908063D0 (en) * 1989-04-11 1989-05-24 Beecham Group Plc Novel compounds
JPH0395153A (ja) * 1989-06-15 1991-04-19 Mitsubishi Kasei Corp ジフェニル尿素誘導体

Also Published As

Publication number Publication date
CZ204692A3 (en) 1993-01-13
NO922564L (no) 1993-01-04
GR3019785T3 (en) 1996-07-31
CA2072704A1 (en) 1993-01-02
DE69208408T2 (de) 1996-07-18
IE73488B1 (en) 1997-06-04
SK204692A3 (en) 1995-02-08
TW213448B (ja) 1993-09-21
KR930002311A (ko) 1993-02-22
ATE134364T1 (de) 1996-03-15
FI923033A (fi) 1993-01-02
DK0528146T3 (da) 1996-05-06
NO922564D0 (no) 1992-06-29
IE922132A1 (en) 1993-01-13
ES2083625T3 (es) 1996-04-16
JPH05221959A (ja) 1993-08-31
ZA924823B (en) 1993-12-29
AU1867792A (en) 1993-01-07
RU2087467C1 (ru) 1997-08-20
EP0528146A1 (en) 1993-02-24
HK73196A (en) 1996-05-03
DE69208408D1 (de) 1996-03-28
RO111933B1 (ro) 1997-03-31
MX9203838A (es) 1993-01-01
FI923033A0 (fi) 1992-06-30
NZ243352A (en) 1995-02-24
EP0528146B1 (en) 1996-02-21
HU9202047D0 (en) 1992-09-28
HUT62558A (en) 1993-05-28
AU657141B2 (en) 1995-03-02

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