IL101242A - Carboxamides their manufacture and pharmaceutical compositions containing them - Google Patents
Carboxamides their manufacture and pharmaceutical compositions containing themInfo
- Publication number
- IL101242A IL101242A IL10124292A IL10124292A IL101242A IL 101242 A IL101242 A IL 101242A IL 10124292 A IL10124292 A IL 10124292A IL 10124292 A IL10124292 A IL 10124292A IL 101242 A IL101242 A IL 101242A
- Authority
- IL
- Israel
- Prior art keywords
- tetrahydro
- oxo
- ethyl
- benzoate
- benzoic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH86391 | 1991-03-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL101242A0 IL101242A0 (en) | 1992-11-15 |
| IL101242A true IL101242A (en) | 1995-12-08 |
Family
ID=4196940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10124292A IL101242A (en) | 1991-03-21 | 1992-03-16 | Carboxamides their manufacture and pharmaceutical compositions containing them |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5216148A (cs) |
| EP (1) | EP0504695A1 (cs) |
| JP (1) | JPH07165709A (cs) |
| KR (1) | KR920018029A (cs) |
| AU (1) | AU649308B2 (cs) |
| BR (1) | BR9200951A (cs) |
| CA (1) | CA2061662A1 (cs) |
| CS (1) | CS83892A3 (cs) |
| FI (1) | FI921135L (cs) |
| HU (1) | HUT60465A (cs) |
| IE (1) | IE920907A1 (cs) |
| IL (1) | IL101242A (cs) |
| IS (1) | IS3823A (cs) |
| MX (1) | MX9201143A (cs) |
| MY (1) | MY131268A (cs) |
| NO (1) | NO921105L (cs) |
| NZ (1) | NZ241953A (cs) |
| TW (1) | TW221425B (cs) |
| UY (1) | UY23386A1 (cs) |
| YU (1) | YU24792A (cs) |
| ZA (1) | ZA921889B (cs) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5599548A (en) * | 1995-05-08 | 1997-02-04 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing fatty acid amides and retinol or retinyl ester |
| ZA9610853B (en) | 1995-12-29 | 1998-04-06 | Smithkline Beecham Corp | Processes and intermediates for preparing pharmaceuticals. |
| US5693330A (en) * | 1996-04-25 | 1997-12-02 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing melinamide and a retinoid |
| US5716627A (en) * | 1996-04-25 | 1998-02-10 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester |
| US5747051A (en) * | 1996-09-27 | 1998-05-05 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an amide of a hydroxy fatty acid and a retinoid |
| US5955092A (en) * | 1996-09-27 | 1999-09-21 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an n-substituted fatty acid amide and retinol or retinyl ester |
| US20040176358A1 (en) * | 1999-04-30 | 2004-09-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| US7144880B2 (en) | 1999-04-30 | 2006-12-05 | Regents Of The University Of Michigan | Compositions relating to novel compounds and targets thereof |
| DK1143946T3 (da) * | 1999-04-30 | 2004-06-07 | Univ Michigan | Anvendelse af benzodiazepiner til behandling af autoimmune sygdomme induceret af apoptose |
| US20050113460A1 (en) * | 1999-04-30 | 2005-05-26 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| US20060025388A1 (en) | 1999-04-30 | 2006-02-02 | Glick Gary D | Compositions and methods relating to novel compounds and targets thereof |
| WO2001035964A1 (en) * | 1999-11-18 | 2001-05-25 | Antexpharma, Inc. | Substituted 1-benzazepines and derivatives thereof |
| TW200508197A (en) * | 2003-03-31 | 2005-03-01 | Ucb Sa | Indolone-acetamide derivatives, processes for preparing them and their uses |
| US20050202055A1 (en) * | 2004-03-11 | 2005-09-15 | Koichi Shudo, Tokyo, Japan | Anti-wrinkle agent |
| US20050272723A1 (en) * | 2004-04-27 | 2005-12-08 | The Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
| US20060052369A1 (en) * | 2004-09-07 | 2006-03-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| EP1845996A4 (en) * | 2005-01-03 | 2009-04-29 | Univ Michigan | COMPOSITIONS AND METHODS RELATED TO NEW CONNECTIONS AND TARGETS THEREFOR |
| US20070043033A1 (en) | 2005-06-01 | 2007-02-22 | The Regents Of The University Of Michigan | Unsolvated benzodiazepine compositions and methods |
| US20070105844A1 (en) * | 2005-10-26 | 2007-05-10 | Regents Of The University Of Michigan | Therapeutic compositions and methods |
| US8088759B2 (en) | 2005-11-01 | 2012-01-03 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones with therapeutic properties |
| US7759338B2 (en) * | 2006-04-27 | 2010-07-20 | The Regents Of The University Of Michigan | Soluble 1,4 benzodiazepine compounds and stable salts thereof |
| CA2659549C (en) | 2006-06-09 | 2013-07-30 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| KR101164718B1 (ko) | 2007-03-09 | 2012-07-11 | 더 리젠츠 오브 더 유니버시티 오브 미시간 | 신규 화합물 및 이의 표적에 관한 조성물 및 방법 |
| ES2614498T3 (es) | 2007-09-14 | 2017-05-31 | The Regents Of The University Of Michigan | Inhibidores de ATPasa F1F0 y métodos relacionados |
| US8188072B2 (en) | 2007-11-06 | 2012-05-29 | The Regents Of The University Of Michigan | Benzodiazepinone compounds useful in the treatment of skin conditions |
| KR101332948B1 (ko) | 2008-02-22 | 2014-01-17 | 오츠카 세이야쿠 가부시키가이샤 | 벤조디아제핀 화합물 및 제약 조성물 |
| AU2009291632B2 (en) | 2008-09-11 | 2013-04-04 | The Regents Of The University Of Michigan | Aryl guanidine F1F0-ATPase inhibitors and related methods |
| US8604023B2 (en) | 2009-04-17 | 2013-12-10 | The Regents Of The University Of Michigan | 1,4-benzodiazepinone compounds and their use in treating cancer |
| TWI481601B (zh) * | 2009-08-21 | 2015-04-21 | Otsuka Pharma Co Ltd | 含氮化合物及藥學組成物 |
| RU2553676C2 (ru) | 2009-08-21 | 2015-06-20 | Оцука Фармасьютикал Ко., Лтд. | СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНОГО БЕНЗО[b][1,4]ДИАЗЕПИН-2,4-ДИОНА |
| EP2470020A4 (en) | 2009-09-18 | 2013-03-13 | Univ Michigan | BENZODIAZEPINONE COMPOUNDS AND TREATMENT METHODS THEREWITH |
| EP2501387B1 (en) | 2009-11-17 | 2016-07-27 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties |
| EP2501695B1 (en) | 2009-11-17 | 2018-08-29 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties |
| CA2797694A1 (en) | 2010-04-29 | 2011-11-03 | The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services | Activators of human pyruvate kinase |
| JP2012184225A (ja) * | 2011-02-18 | 2012-09-27 | Otsuka Pharmaceut Co Ltd | 医薬組成物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3803775A1 (de) * | 1988-02-09 | 1989-08-17 | Boehringer Mannheim Gmbh | Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
| DE3818830A1 (de) * | 1988-06-03 | 1989-12-14 | Boehringer Mannheim Gmbh | Bicyclische carboxamide, verfahren zu ihrer herstellung, deren vorstufen, und diese verbindungen enthaltende arzneimittel |
| AU626881B2 (en) * | 1988-07-14 | 1992-08-13 | F. Hoffmann-La Roche Ag | Benzofused heterocyclics used as pharmaceuticals |
-
1991
- 1991-03-19 BR BR929200951A patent/BR9200951A/pt not_active Application Discontinuation
-
1992
- 1992-02-20 AU AU11089/92A patent/AU649308B2/en not_active Ceased
- 1992-02-20 TW TW081101237A patent/TW221425B/zh active
- 1992-02-21 CA CA002061662A patent/CA2061662A1/en not_active Abandoned
- 1992-02-27 US US07/842,662 patent/US5216148A/en not_active Expired - Fee Related
- 1992-03-09 EP EP92103970A patent/EP0504695A1/de not_active Withdrawn
- 1992-03-12 YU YU24792A patent/YU24792A/sh unknown
- 1992-03-13 NZ NZ241953A patent/NZ241953A/en unknown
- 1992-03-13 ZA ZA921889A patent/ZA921889B/xx unknown
- 1992-03-16 HU HU9200871A patent/HUT60465A/hu unknown
- 1992-03-16 IL IL10124292A patent/IL101242A/en not_active IP Right Cessation
- 1992-03-16 MX MX9201143A patent/MX9201143A/es not_active IP Right Cessation
- 1992-03-17 FI FI921135A patent/FI921135L/fi not_active Application Discontinuation
- 1992-03-17 JP JP4090152A patent/JPH07165709A/ja active Pending
- 1992-03-19 CS CS92838A patent/CS83892A3/cs unknown
- 1992-03-19 MY MYPI92000458A patent/MY131268A/en unknown
- 1992-03-20 IE IE090792A patent/IE920907A1/en unknown
- 1992-03-20 NO NO92921105A patent/NO921105L/no unknown
- 1992-03-20 KR KR1019920004612A patent/KR920018029A/ko not_active Withdrawn
- 1992-03-20 UY UY23386A patent/UY23386A1/es not_active IP Right Cessation
- 1992-03-20 IS IS3823A patent/IS3823A/is unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW221425B (cs) | 1994-03-01 |
| YU24792A (sh) | 1994-09-09 |
| MY131268A (en) | 2007-07-31 |
| UY23386A1 (es) | 1992-11-05 |
| JPH07165709A (ja) | 1995-06-27 |
| CA2061662A1 (en) | 1992-09-22 |
| NO921105D0 (no) | 1992-03-20 |
| IS3823A (is) | 1992-09-22 |
| HU9200871D0 (en) | 1992-05-28 |
| ZA921889B (en) | 1992-11-25 |
| IE920907A1 (en) | 1992-09-23 |
| CS83892A3 (en) | 1992-10-14 |
| EP0504695A1 (de) | 1992-09-23 |
| NZ241953A (en) | 1994-11-25 |
| FI921135A7 (fi) | 1992-09-22 |
| FI921135A0 (fi) | 1992-03-17 |
| US5216148A (en) | 1993-06-01 |
| FI921135L (fi) | 1992-09-22 |
| IL101242A0 (en) | 1992-11-15 |
| HUT60465A (en) | 1992-09-28 |
| AU1108992A (en) | 1992-09-24 |
| MX9201143A (es) | 1992-10-01 |
| BR9200951A (pt) | 1992-11-17 |
| AU649308B2 (en) | 1994-05-19 |
| KR920018029A (ko) | 1992-10-21 |
| NO921105L (no) | 1992-09-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL101242A (en) | Carboxamides their manufacture and pharmaceutical compositions containing them | |
| US5480873A (en) | Pharmaceutical compounds | |
| US6342602B1 (en) | Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thichroman and 1,2,3,4-tetrahydroquinolinecarboxlic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity | |
| US5767283A (en) | 7-Amino-1H-indoles | |
| KR19990071542A (ko) | 레티노이드형 생리활성을 갖는 테트라히드로나프타렌, 크로만,티오크로만 및 1,2,3,4-테트라히드퀴놀린 카르복실산의 아릴 또는 헤테로아릴 아미드 | |
| DK155730B (da) | Analogifremgangsmaade til fremstilling af polyenforbindelser | |
| IE63436B1 (en) | Novel benzocycloheptene derivatives their preparation and there use as pharmaceuticals | |
| IE49350B1 (en) | Tetrahydroquinoline-2-carboxylic acids and their salts | |
| US3960911A (en) | Ferrocene compounds and preparation | |
| HU219241B (en) | Amide derivatives, their preparation, intermediates and pharmaceutical compns. contg. the said amide derivatives | |
| US5061718A (en) | Benzothiazolylmethoxy compounds, pharmaceutical compositions comprising the same and their use as anti-inflammatory or anti-allergenic agents | |
| WO2002000638A2 (en) | Substituted phthalides as anti-convulsive drugs | |
| IL95144A (en) | Aromatic carboxamides, their preparation and pharmaceutical compositions containing them | |
| JPS6037116B2 (ja) | ２―置換オキサゾロピリジン | |
| US5719180A (en) | Chroman derivatives having vitamin E-like activities | |
| NZ241197A (en) | Substituted benz[b]azepine derivatives and pharmaceutical compositions | |
| US5990329A (en) | Retinoids | |
| US4057640A (en) | 5,6,7,8:Tetrahydrocarbazole-1-carboxylic acid derivatives | |
| HU177901B (en) | Process for preparing 8- and/or 9-substituted 2,3,4,5-tetrahydro-1h-2-benzazepine derivatives | |
| SI9210247A (sl) | Novi amidi karboksilne kisline | |
| US5216153A (en) | Aromatic carboxamides | |
| JPS59193873A (ja) | ヘテロ環化合物 | |
| JPS5910547A (ja) | ポリエン化合物 | |
| JPH09100270A (ja) | レチノイドアンタゴニスト | |
| HK1039121A1 (en) | Tetrahydroquinoline derivatives having selective activity for retinoid x receptors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| RH | Patent void |