IL100702A - (S)-1-[(10-chloro-6,7-dihydro-4-oxo-3-phenyl-4h-benzo [a] quinolizin-1-yl) carbonyl] 3-ethoxypyrrolidine its preparation and pharmaceutical compositions containing it - Google Patents

(S)-1-[(10-chloro-6,7-dihydro-4-oxo-3-phenyl-4h-benzo [a] quinolizin-1-yl) carbonyl] 3-ethoxypyrrolidine its preparation and pharmaceutical compositions containing it

Info

Publication number
IL100702A
IL100702A IL10070292A IL10070292A IL100702A IL 100702 A IL100702 A IL 100702A IL 10070292 A IL10070292 A IL 10070292A IL 10070292 A IL10070292 A IL 10070292A IL 100702 A IL100702 A IL 100702A
Authority
IL
Israel
Prior art keywords
compound
formula
ethoxypyrrolidine
benzo
dihydro
Prior art date
Application number
IL10070292A
Other languages
English (en)
Other versions
IL100702A0 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL100702A0 publication Critical patent/IL100702A0/xx
Publication of IL100702A publication Critical patent/IL100702A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C07D455/06—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine containing benzo [a] quinolizine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/15—Suppositories

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electric Propulsion And Braking For Vehicles (AREA)
IL10070292A 1991-01-25 1992-01-20 (S)-1-[(10-chloro-6,7-dihydro-4-oxo-3-phenyl-4h-benzo [a] quinolizin-1-yl) carbonyl] 3-ethoxypyrrolidine its preparation and pharmaceutical compositions containing it IL100702A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH22891 1991-01-25

Publications (2)

Publication Number Publication Date
IL100702A0 IL100702A0 (en) 1992-09-06
IL100702A true IL100702A (en) 1995-08-31

Family

ID=4182207

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10070292A IL100702A (en) 1991-01-25 1992-01-20 (S)-1-[(10-chloro-6,7-dihydro-4-oxo-3-phenyl-4h-benzo [a] quinolizin-1-yl) carbonyl] 3-ethoxypyrrolidine its preparation and pharmaceutical compositions containing it

Country Status (30)

Country Link
US (2) US5281711A (cs)
EP (1) EP0496274B1 (cs)
JP (1) JPH0739415B2 (cs)
KR (1) KR920014811A (cs)
AT (1) ATE140002T1 (cs)
AU (1) AU649302B2 (cs)
BG (1) BG61057B2 (cs)
BR (1) BR9200217A (cs)
CA (1) CA2058640A1 (cs)
CZ (1) CZ280258B6 (cs)
DE (1) DE59206676D1 (cs)
DK (1) DK0496274T3 (cs)
ES (1) ES2089252T3 (cs)
FI (1) FI920268A7 (cs)
GR (1) GR3021126T3 (cs)
HU (2) HU207072B (cs)
IE (1) IE920225A1 (cs)
IL (1) IL100702A (cs)
IS (1) IS3804A (cs)
LT (1) LT3473B (cs)
LV (1) LV10275B (cs)
MX (1) MX9200242A (cs)
MY (1) MY108199A (cs)
NO (1) NO920338L (cs)
NZ (1) NZ241341A (cs)
RU (1) RU2073678C1 (cs)
SI (1) SI9210067A (cs)
UY (1) UY23362A1 (cs)
YU (1) YU48221B (cs)
ZA (1) ZA92361B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0650966A1 (de) * 1993-10-28 1995-05-03 F. Hoffmann-La Roche Ag Verfahren zur Herstellung eines Benzo(a)chinolizinon-Derivates
KR100295740B1 (ko) 1998-09-17 2001-11-05 박영구 N-치환된-하이드록시고리화알킬아민유도체의제조방법
US7277767B2 (en) 1999-12-10 2007-10-02 Srs Labs, Inc. System and method for enhanced streaming audio
GB2410947B (en) * 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds
DE602006004009D1 (de) * 2005-08-06 2009-01-15 Cambridge Lab Ireland Ltd 3,11b-cis-dihydrotetrabanezin zur behandlung von schizophrenie und anderen psychosen
WO2010058429A1 (en) 2008-11-24 2010-05-27 Council Of Scientific & Industrial Research A process for the preparation of optically active n-benzyl-3 hydroxypyrrolidines
WO2014190140A1 (en) 2013-05-23 2014-11-27 Alan Kraemer Headphone audio enhancement system

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU191427B (en) * 1984-07-16 1987-02-27 Budapesti Mueszaki Egyetem,Hu Piezooptical effect reduced electrooptical light modulator
US4889848A (en) * 1984-11-06 1989-12-26 Hoffmann-La Roche Inc. Tricyclic pyridine derivatives
ZW17385A1 (en) * 1984-11-06 1986-02-19 Hoffmann La Roche Tricyclic pyridine derivatives
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent

Also Published As

Publication number Publication date
DE59206676D1 (de) 1996-08-08
LV10275B (en) 1995-02-20
HU207072B (en) 1993-03-01
MX9200242A (es) 1992-07-01
UY23362A1 (es) 1992-07-21
KR920014811A (ko) 1992-08-25
HU211259A9 (en) 1995-11-28
SI9210067A (en) 1995-02-28
MY108199A (en) 1996-08-30
HU9200128D0 (en) 1992-04-28
ZA92361B (en) 1992-09-30
FI920268L (fi) 1992-07-26
CZ280258B6 (cs) 1995-12-13
RU2073678C1 (ru) 1997-02-20
NO920338L (no) 1992-07-27
NZ241341A (en) 1993-12-23
BR9200217A (pt) 1992-10-06
YU48221B (sh) 1997-08-22
US5326769A (en) 1994-07-05
JPH04312585A (ja) 1992-11-04
DK0496274T3 (da) 1996-09-23
IE920225A1 (en) 1992-07-29
EP0496274B1 (de) 1996-07-03
US5281711A (en) 1994-01-25
LTIP801A (en) 1995-02-27
BG61057B2 (bg) 1996-09-30
YU6792A (sh) 1994-11-15
CS18292A3 (en) 1992-08-12
FI920268A7 (fi) 1992-07-26
ES2089252T3 (es) 1996-10-01
IS3804A (is) 1992-07-26
LV10275A (lv) 1994-10-20
JPH0739415B2 (ja) 1995-05-01
LT3473B (en) 1995-10-25
FI920268A0 (fi) 1992-01-22
AU649302B2 (en) 1994-05-19
GR3021126T3 (en) 1996-12-31
ATE140002T1 (de) 1996-07-15
IL100702A0 (en) 1992-09-06
NO920338D0 (no) 1992-01-24
EP0496274A1 (de) 1992-07-29
CA2058640A1 (en) 1992-07-26
AU1034092A (en) 1992-07-30
HUT60266A (en) 1992-08-28

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