IL100580A0 - Chemical process - Google Patents
Chemical processInfo
- Publication number
- IL100580A0 IL100580A0 IL100580A IL10058092A IL100580A0 IL 100580 A0 IL100580 A0 IL 100580A0 IL 100580 A IL100580 A IL 100580A IL 10058092 A IL10058092 A IL 10058092A IL 100580 A0 IL100580 A0 IL 100580A0
- Authority
- IL
- Israel
- Prior art keywords
- chemical process
- chemical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919101026A GB9101026D0 (en) | 1991-01-17 | 1991-01-17 | Chemical process |
| GB919106876A GB9106876D0 (en) | 1991-04-02 | 1991-04-02 | Manufacturing process |
| GB919121726A GB9121726D0 (en) | 1991-10-14 | 1991-10-14 | Process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL100580A0 true IL100580A0 (en) | 1992-09-06 |
Family
ID=27265456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL100580A IL100580A0 (en) | 1991-01-17 | 1992-01-03 | Chemical process |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US5294716A (xx) |
| EP (1) | EP0495626A1 (xx) |
| JP (1) | JPH0559042A (xx) |
| KR (1) | KR920014800A (xx) |
| AU (1) | AU9012091A (xx) |
| CA (1) | CA2058899A1 (xx) |
| CS (1) | CS9992A3 (xx) |
| FI (1) | FI920212A (xx) |
| GB (1) | GB9200758D0 (xx) |
| HU (1) | HUT60262A (xx) |
| IE (1) | IE914572A1 (xx) |
| IL (1) | IL100580A0 (xx) |
| NO (1) | NO920222L (xx) |
| PT (1) | PT100022A (xx) |
| ZW (1) | ZW792A1 (xx) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE914572A1 (en) * | 1991-01-17 | 1992-07-29 | Zeneca Ltd | Chemical process |
| US5602127A (en) * | 1991-02-06 | 1997-02-11 | Karl Thomae Gmbh | (Alkanesultam-1-yl)-benzimidazol-1-yl)-1yl)-methyl-biphenyls useful as angiotensin-II antagonists |
| US5614519A (en) * | 1991-02-06 | 1997-03-25 | Karl Thomae Gmbh | (1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists |
| US5594003A (en) * | 1991-02-06 | 1997-01-14 | Dr. Karl Thomae Gmbh | Tetrahydroimidazo[1,2-a]pyridin-2-yl-(benzimidazol-1-yl)-methyl-biphenyls useful as angiotensin-II antagonists |
| US5616599A (en) * | 1991-02-21 | 1997-04-01 | Sankyo Company, Limited | Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use |
| US5252753A (en) * | 1991-11-01 | 1993-10-12 | Ortho Pharmaceutical Corporation | Process for the preparation of certain substituted biphenyl tetrazoles and compounds thereof |
| DE69233734D1 (de) * | 1991-11-18 | 2008-06-26 | Du Pont | 2-(2'-Triphenylmethyl-2'H-tetrazol-5'-yl)phenylborsäure als Zwischenprodukt zur Synthese von A II Receptorenantagonisten |
| GB9201715D0 (en) * | 1992-01-28 | 1992-03-11 | Ici Plc | Chemical process |
| JP3501484B2 (ja) * | 1992-12-17 | 2004-03-02 | 三共株式会社 | ビフェニル誘導体 |
| JPWO2003030937A1 (ja) * | 2001-10-05 | 2005-01-20 | 小野薬品工業株式会社 | ミトコンドリアルベンゾジアゼピン受容体アンタゴニストからなるストレス疾患の治療剤 |
| ES2259412T3 (es) * | 2002-04-29 | 2006-10-01 | Teva Pharmaceutical Industries Ltd. | Procedimientos para la preparacion de losartan y losartan potasico. |
| CN1976926A (zh) * | 2004-09-02 | 2007-06-06 | 特瓦制药工业有限公司 | 奥美沙坦酯的制备 |
| US20070054948A1 (en) * | 2004-09-02 | 2007-03-08 | Lilach Hedvati | Purification of olmesartan medoxomil |
| KR100953878B1 (ko) * | 2004-09-02 | 2010-04-22 | 테바 파마슈티컬 인더스트리즈 리미티드 | 올메살탄 메독소밀의 정제 |
| US20060258727A1 (en) * | 2005-01-03 | 2006-11-16 | Lilach Hedvati | Olmesartan medoxomil with reduced levels of impurities |
| MX354786B (es) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos. |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| WO2010009319A2 (en) | 2008-07-16 | 2010-01-21 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| WO2012119035A1 (en) * | 2011-03-03 | 2012-09-07 | Treventis Corporation | Anti-amyloid compounds and methods |
| CN104487427B (zh) * | 2012-06-25 | 2017-03-15 | 萨尼奥纳有限责任公司 | 四唑衍生物和它们作为钾通道调节剂的用途 |
| WO2014151200A2 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| JP6606491B2 (ja) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法 |
| WO2020140001A1 (en) * | 2018-12-28 | 2020-07-02 | Riboscience Llc | Quinazoline derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors |
| ES2960987T3 (es) | 2019-04-12 | 2024-03-07 | Riboscience Llc | Derivados de heteroarilo bicíclicos como inhibidores de la ectonucleótido pirofosfatasa fosfodiesterasa 1 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
| US4820843A (en) * | 1987-05-22 | 1989-04-11 | E. I. Du Pont De Nemours And Company | Tetrazole intermediates to antihypertensive compounds |
| DE69016125T2 (de) * | 1989-08-11 | 1995-06-01 | Zeneca Ltd | Chinolin-Derivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel. |
| GB2244054B (en) * | 1990-04-19 | 1994-04-06 | Ici Plc | Pyridine derivatives |
| IE914572A1 (en) * | 1991-01-17 | 1992-07-29 | Zeneca Ltd | Chemical process |
| US5252753A (en) * | 1991-11-01 | 1993-10-12 | Ortho Pharmaceutical Corporation | Process for the preparation of certain substituted biphenyl tetrazoles and compounds thereof |
-
1991
- 1991-12-30 IE IE457291A patent/IE914572A1/en not_active Application Discontinuation
- 1991-12-31 AU AU90120/91A patent/AU9012091A/en not_active Abandoned
-
1992
- 1992-01-03 IL IL100580A patent/IL100580A0/xx unknown
- 1992-01-07 CA CA002058899A patent/CA2058899A1/en not_active Abandoned
- 1992-01-13 ZW ZW7/92A patent/ZW792A1/xx unknown
- 1992-01-14 GB GB929200758A patent/GB9200758D0/en active Pending
- 1992-01-14 EP EP92300307A patent/EP0495626A1/en not_active Withdrawn
- 1992-01-14 CS CS9299A patent/CS9992A3/cs unknown
- 1992-01-15 HU HU929200130A patent/HUT60262A/hu unknown
- 1992-01-16 NO NO92920222A patent/NO920222L/no unknown
- 1992-01-16 PT PT100022A patent/PT100022A/pt not_active Application Discontinuation
- 1992-01-16 KR KR1019920000687A patent/KR920014800A/ko not_active Application Discontinuation
- 1992-01-17 JP JP4006874A patent/JPH0559042A/ja active Pending
- 1992-01-17 US US07/822,395 patent/US5294716A/en not_active Expired - Fee Related
- 1992-01-17 FI FI920212A patent/FI920212A/fi not_active Application Discontinuation
-
1994
- 1994-01-31 US US08/189,954 patent/US5420292A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HU9200130D0 (en) | 1992-04-28 |
| GB9200758D0 (en) | 1992-03-11 |
| ZW792A1 (en) | 1992-09-30 |
| US5420292A (en) | 1995-05-30 |
| HUT60262A (en) | 1992-08-28 |
| JPH0559042A (ja) | 1993-03-09 |
| FI920212A0 (fi) | 1992-01-17 |
| PT100022A (pt) | 1993-02-26 |
| AU9012091A (en) | 1992-07-23 |
| KR920014800A (ko) | 1992-08-25 |
| NO920222D0 (no) | 1992-01-16 |
| IE914572A1 (en) | 1992-07-29 |
| CA2058899A1 (en) | 1992-07-18 |
| CS9992A3 (en) | 1992-08-12 |
| EP0495626A1 (en) | 1992-07-22 |
| NO920222L (no) | 1992-07-20 |
| US5294716A (en) | 1994-03-15 |
| FI920212A (fi) | 1992-07-18 |
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