IL100575A - Antibiotics 1-Karba-1-Datia (-Safam and pharmaceutical preparations containing them - Google Patents
Antibiotics 1-Karba-1-Datia (-Safam and pharmaceutical preparations containing themInfo
- Publication number
- IL100575A IL100575A IL10057592A IL10057592A IL100575A IL 100575 A IL100575 A IL 100575A IL 10057592 A IL10057592 A IL 10057592A IL 10057592 A IL10057592 A IL 10057592A IL 100575 A IL100575 A IL 100575A
- Authority
- IL
- Israel
- Prior art keywords
- amino
- formula
- compound
- alkyl
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/643,244 US5077287A (en) | 1991-01-18 | 1991-01-18 | 3-thiazolylthio carbacephem antibacterial agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL100575A0 IL100575A0 (en) | 1992-09-06 |
| IL100575A true IL100575A (en) | 1996-11-14 |
Family
ID=24579974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10057592A IL100575A (en) | 1991-01-18 | 1992-01-01 | Antibiotics 1-Karba-1-Datia (-Safam and pharmaceutical preparations containing them |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5077287A (fr) |
| EP (1) | EP0495585A1 (fr) |
| JP (1) | JPH04321686A (fr) |
| KR (1) | KR920014810A (fr) |
| CN (1) | CN1063284A (fr) |
| AU (1) | AU642334B2 (fr) |
| BR (1) | BR9200058A (fr) |
| CA (1) | CA2058592C (fr) |
| CZ (1) | CZ281909B6 (fr) |
| FI (1) | FI920110A (fr) |
| HU (1) | HUT60268A (fr) |
| IE (1) | IE920084A1 (fr) |
| IL (1) | IL100575A (fr) |
| MX (1) | MX9200105A (fr) |
| MY (1) | MY131300A (fr) |
| NO (1) | NO301328B1 (fr) |
| NZ (1) | NZ241250A (fr) |
| PT (1) | PT99984B (fr) |
| RU (1) | RU2107067C1 (fr) |
| YU (1) | YU2392A (fr) |
| ZA (1) | ZA9225B (fr) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5272265A (en) * | 1990-02-12 | 1993-12-21 | Eli Lilly And Company | 3-(substituted or unsubstituted) thiazolo-1-carba (1-dethia)cephems |
| US5179088A (en) * | 1990-02-12 | 1993-01-12 | Eli Lilly And Company | 1-carba(dethia)cephalosporin antibiotics |
| IL100576A (en) * | 1991-01-18 | 1995-11-27 | Eli Lilley And Company | Cephalosporin antibiotics |
| JP3238209B2 (ja) * | 1992-09-30 | 2001-12-10 | 塩野義製薬株式会社 | チオメチルチオカルバセファロスポリン誘導体 |
| US5525599A (en) * | 1993-07-21 | 1996-06-11 | Eli Lilly And Company | 7-substituted-amino-3-substituted-3-cephem-4-carboxylic acids |
| DE4333697A1 (de) * | 1993-10-02 | 1995-04-06 | Merck Patent Gmbh | Verfahren zur Herstellung von 3-Aminopyridinen aus 3-Nitropyridinen |
| US5496816A (en) * | 1994-03-14 | 1996-03-05 | Merck & Co., Inc. | Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment |
| US5698547A (en) * | 1994-04-01 | 1997-12-16 | Microcide Pharmaceuticals, Inc. | Cephalosporin antibiotics |
| US5688786A (en) * | 1994-04-01 | 1997-11-18 | Microcide Pharmaceuticals, Inc. | β-lactam antibiotics |
| CZ287296A3 (en) * | 1994-04-01 | 1997-05-14 | Microcide Pharmaceuticals | Cephalosporin antibiotics and antibacterial preparations in which they are comprised |
| US5498777A (en) * | 1994-07-20 | 1996-03-12 | Merck & Co., Inc. | 3-thioheteroaryl cephalosporin compounds, compositions and methods of use |
| US5565445A (en) * | 1995-02-22 | 1996-10-15 | Merck & Co., Inc. | 3-thioheteroaryl 1-carba-1-dethiacephalosporin compounds, compositions and methods of use |
| WO1996038450A1 (fr) * | 1995-05-31 | 1996-12-05 | Microcide Pharmaceuticals, Inc. | Cephalosporines |
| MY127641A (en) * | 1995-10-12 | 2006-12-29 | Essential Therapeutics Inc | Cephalosporin antibiotics |
| WO1998046566A1 (fr) * | 1997-04-17 | 1998-10-22 | Microcide Pharmaceuticals, Inc. | ANTIBIOTIQUES DE β-LACTAME AMELIORES |
| US6025352A (en) * | 1997-09-29 | 2000-02-15 | Microcide Pharmaceuticals, Inc. | Cephalosporin antibiotics |
| US6030965A (en) * | 1997-09-30 | 2000-02-29 | Microcide Pharmaceuticals, Inc. | Cephalosporin antibiotics |
| US6362009B1 (en) | 1997-11-21 | 2002-03-26 | Merck & Co., Inc. | Solid phase synthesis of heterocycles |
| JP2006525340A (ja) * | 2003-04-30 | 2006-11-09 | トライン・ファーマシューティカルズ・インコーポレイテッド | カルバセフェムβ−ラクタム系抗生物質 |
| US20080146535A1 (en) * | 2003-04-30 | 2008-06-19 | Tomasz Glinka | Compositions comprising carbacephem beta-lactam antibiotics and beta-lactamase inhibitors |
| KR20100093532A (ko) * | 2007-10-25 | 2010-08-25 | 아카오젠, 인코포레이티드 | 카바세펨 β―락탐 항생제 |
| WO2010030810A1 (fr) * | 2008-09-10 | 2010-03-18 | Achaogen, Inc. | Antibiotiques de type béta-lactame à base de carbacéphème |
| WO2010123997A1 (fr) * | 2009-04-22 | 2010-10-28 | Achaogen, Inc. | Antibiotiques bêta-lactames carbacéphèmes |
| WO2011103441A1 (fr) | 2010-02-18 | 2011-08-25 | Schering Corporation | Dérivés de pyridine et pyrimidine substitués et leur utilisation dans le traitement d'infections virales |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA766941B (en) * | 1975-11-21 | 1978-06-28 | Merck & Co Inc | 3-(substituted thio)cephalosporins,derivatives and nuclear analogues thereof |
| JPS6058920B2 (ja) * | 1978-12-26 | 1985-12-23 | 協和醗酵工業株式会社 | セフアロスポリン類縁体 |
| JPS60174787A (ja) * | 1984-02-21 | 1985-09-09 | Kyowa Hakko Kogyo Co Ltd | ３位置換カルバセフエム化合物 |
| JPH0653739B2 (ja) * | 1984-11-15 | 1994-07-20 | 協和醗酵工業株式会社 | ３位置換カルバセフエム化合物 |
| US4885291A (en) * | 1988-01-14 | 1989-12-05 | Eli Lilly And Company | 1-carba(dethia)-3-cephem derivatives |
| IL100576A (en) * | 1991-01-18 | 1995-11-27 | Eli Lilley And Company | Cephalosporin antibiotics |
-
1991
- 1991-01-18 US US07/643,244 patent/US5077287A/en not_active Expired - Lifetime
-
1992
- 1992-01-01 IL IL10057592A patent/IL100575A/en not_active IP Right Cessation
- 1992-01-02 ZA ZA9225A patent/ZA9225B/xx unknown
- 1992-01-03 CZ CS9211A patent/CZ281909B6/cs unknown
- 1992-01-06 CA CA002058592A patent/CA2058592C/fr not_active Expired - Fee Related
- 1992-01-07 PT PT99984A patent/PT99984B/pt not_active IP Right Cessation
- 1992-01-08 MY MYPI92000033A patent/MY131300A/en unknown
- 1992-01-08 NO NO920103A patent/NO301328B1/no not_active IP Right Cessation
- 1992-01-08 NZ NZ241250A patent/NZ241250A/xx unknown
- 1992-01-09 AU AU10135/92A patent/AU642334B2/en not_active Ceased
- 1992-01-09 EP EP92300182A patent/EP0495585A1/fr not_active Ceased
- 1992-01-09 JP JP4002224A patent/JPH04321686A/ja active Pending
- 1992-01-09 HU HU9200081A patent/HUT60268A/hu unknown
- 1992-01-09 KR KR1019920000198A patent/KR920014810A/ko not_active Application Discontinuation
- 1992-01-10 IE IE008492A patent/IE920084A1/en unknown
- 1992-01-10 FI FI920110A patent/FI920110A/fi not_active Application Discontinuation
- 1992-01-10 MX MX9200105A patent/MX9200105A/es unknown
- 1992-01-10 CN CN92100136A patent/CN1063284A/zh active Pending
- 1992-01-10 BR BR929200058A patent/BR9200058A/pt not_active Application Discontinuation
- 1992-01-10 YU YU2392A patent/YU2392A/sh unknown
-
1993
- 1993-01-22 RU RU93004457A patent/RU2107067C1/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| CZ281909B6 (cs) | 1997-03-12 |
| JPH04321686A (ja) | 1992-11-11 |
| FI920110A (fi) | 1992-07-19 |
| IE920084A1 (en) | 1992-07-29 |
| EP0495585A1 (fr) | 1992-07-22 |
| CA2058592A1 (fr) | 1992-07-19 |
| NZ241250A (en) | 1993-02-25 |
| HUT60268A (en) | 1992-08-28 |
| FI920110A0 (fi) | 1992-01-10 |
| RU2107067C1 (ru) | 1998-03-20 |
| ZA9225B (en) | 1993-07-02 |
| MX9200105A (es) | 1992-07-01 |
| MY131300A (en) | 2007-08-30 |
| AU1013592A (en) | 1992-07-23 |
| NO301328B1 (no) | 1997-10-13 |
| CS1192A3 (en) | 1992-08-12 |
| YU2392A (sh) | 1994-12-28 |
| AU642334B2 (en) | 1993-10-14 |
| CN1063284A (zh) | 1992-08-05 |
| NO920103D0 (no) | 1992-01-08 |
| PT99984A (pt) | 1993-01-29 |
| BR9200058A (pt) | 1992-09-08 |
| HU9200081D0 (en) | 1992-03-30 |
| NO920103L (no) | 1992-07-20 |
| CA2058592C (fr) | 2001-12-25 |
| IL100575A0 (en) | 1992-09-06 |
| KR920014810A (ko) | 1992-08-25 |
| PT99984B (pt) | 1999-06-30 |
| US5077287A (en) | 1991-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| RH | Patent void |