IE913790A1 - SUBSTITUTED INDOLIZINO [1,2-b]QUINOLINONES - Google Patents

SUBSTITUTED INDOLIZINO [1,2-b]QUINOLINONES

Info

Publication number
IE913790A1
IE913790A1 IE379091A IE379091A IE913790A1 IE 913790 A1 IE913790 A1 IE 913790A1 IE 379091 A IE379091 A IE 379091A IE 379091 A IE379091 A IE 379091A IE 913790 A1 IE913790 A1 IE 913790A1
Authority
IE
Ireland
Prior art keywords
compound
quinolin
lower alkyl
oxopropyl
nrr
Prior art date
Application number
IE379091A
Other languages
English (en)
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of IE913790A1 publication Critical patent/IE913790A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IE379091A 1990-10-31 1991-10-30 SUBSTITUTED INDOLIZINO [1,2-b]QUINOLINONES IE913790A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60621690A 1990-10-31 1990-10-31
US78306391A 1991-10-25 1991-10-25

Publications (1)

Publication Number Publication Date
IE913790A1 true IE913790A1 (en) 1992-05-22

Family

ID=27085175

Family Applications (1)

Application Number Title Priority Date Filing Date
IE379091A IE913790A1 (en) 1990-10-31 1991-10-30 SUBSTITUTED INDOLIZINO [1,2-b]QUINOLINONES

Country Status (9)

Country Link
EP (1) EP0555347A4 (fr)
JP (1) JPH06502642A (fr)
KR (1) KR930702289A (fr)
AU (1) AU8940491A (fr)
CA (1) CA2095219A1 (fr)
IE (1) IE913790A1 (fr)
NZ (1) NZ240406A (fr)
PT (1) PT99412A (fr)
WO (1) WO1992007856A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883255A (en) * 1990-10-31 1999-03-16 Smithkline Beecham Corporation Substituted indolizino 1,2-b!quinolinones
CA2118324A1 (fr) * 1992-04-17 1993-10-28 David A. Berges Indolizino¬1,2-b|quinolinones substituees
AU684777B2 (en) * 1993-05-03 1998-01-08 Smithkline Beecham Corporation Substituted methylenedioxy(3',4':6,7)indolizino-(1,2-b)quinolinones
US5491237A (en) * 1994-05-03 1996-02-13 Glaxo Wellcome Inc. Intermediates in pharmaceutical camptothecin preparation
CA2215178A1 (fr) * 1995-06-27 1997-01-16 Takeda Chemical Industries, Ltd. Derives de 4-acylamino(halogeno)alkyl-quinoline, leur preparation et leur utilisation comme agonistes de la melatonine
DE69635057T2 (de) * 1995-11-02 2006-06-01 Osi Pharmaceuticals, Inc. Verfahren zur herstellung von camptothecin-derivaten
US6559309B2 (en) 1996-11-01 2003-05-06 Osi Pharmaceuticals, Inc. Preparation of a camptothecin derivative by intramolecular cyclisation
JP3046258B2 (ja) * 1997-04-11 2000-05-29 株式会社ヤクルト本社 １−クロロカルボニル−４−ピペリジノピペリジンまたはその塩酸塩の製造方法
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
JP5082033B2 (ja) 2001-12-21 2012-11-28 エグゼリクシス パテント カンパニー エルエルシー Ｌｘｒのモジュレーター
US20040077674A1 (en) * 2002-03-01 2004-04-22 Curran Dennis P. Mappicine analogs, intermediates in the synthesis of mappicine analogs and methods of synthesis of mappicine analogs
US7064202B1 (en) * 2003-05-12 2006-06-20 University Of Kentucky Research Foundation Camptothecin intermediates and prodrugs and methods of preparation thereof
US20050267141A1 (en) 2004-05-28 2005-12-01 Phytogen Life Sciences Inc. Process to prepare camptothecin derivatives
US20050272757A1 (en) * 2004-06-04 2005-12-08 Phytogen Life Sciences Inc. Process to prepare camptothecin derivatives and novel intermediate and compounds thereof
WO2006019955A2 (fr) 2004-07-14 2006-02-23 President And Fellows Of Harvard College Methodes et compositions antivirales
US9888690B2 (en) 2011-06-22 2018-02-13 Council Of Scientific & Industrial Research Insecticidal compounds from Nothapodites foetida and process for the extraction thereof
KR101721029B1 (ko) 2014-10-16 2017-03-29 연세대학교 산학협력단 인돌리지노[3,2-c]퀴놀린 유도체, 이의 약제학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 포함하는 낭포성 섬유증 예방 또는 치료용 약학조성물
WO2017014601A1 (fr) * 2015-07-23 2017-01-26 서울대학교 산학협력단 Sonde de fluorescence à base d'indolizino [3,2-c] quinoline
KR101850607B1 (ko) 2015-07-23 2018-04-19 서울대학교산학협력단 인돌리지노[3,2-ｃ]퀴놀린계 형광 프로브

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5829793B2 (ja) * 1975-02-07 1983-06-24 日本ケミフア （株） ７−アルコキシカルボニル−８−メチルインドリジノ〔１，２−ｂ〕キノリン−９（１１Ｈ）−オンの製法

Also Published As

Publication number Publication date
PT99412A (pt) 1992-10-30
AU8940491A (en) 1992-05-26
JPH06502642A (ja) 1994-03-24
EP0555347A1 (fr) 1993-08-18
CA2095219A1 (fr) 1992-05-01
KR930702289A (ko) 1993-09-08
NZ240406A (en) 1994-05-26
EP0555347A4 (en) 1995-01-11
WO1992007856A1 (fr) 1992-05-14

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Legal Events

Date Code Title Description
FC9A Application refused sect. 31(1)