IE56485B1 - Improvements in or relating to novel cephalosporin intermediates - Google Patents

Improvements in or relating to novel cephalosporin intermediates

Info

Publication number
IE56485B1
IE56485B1 IE3037/83A IE303783A IE56485B1 IE 56485 B1 IE56485 B1 IE 56485B1 IE 3037/83 A IE3037/83 A IE 3037/83A IE 303783 A IE303783 A IE 303783A IE 56485 B1 IE56485 B1 IE 56485B1
Authority
IE
Ireland
Prior art keywords
formula
compound
ceftazidime
dimethylacetamide
solvent
Prior art date
Application number
IE3037/83A
Other languages
English (en)
Other versions
IE833037L (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IE833037L publication Critical patent/IE833037L/en
Publication of IE56485B1 publication Critical patent/IE56485B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
IE3037/83A 1982-12-27 1983-12-22 Improvements in or relating to novel cephalosporin intermediates IE56485B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45344582A 1982-12-27 1982-12-27

Publications (2)

Publication Number Publication Date
IE833037L IE833037L (en) 1984-06-27
IE56485B1 true IE56485B1 (en) 1991-08-14

Family

ID=23800618

Family Applications (1)

Application Number Title Priority Date Filing Date
IE3037/83A IE56485B1 (en) 1982-12-27 1983-12-22 Improvements in or relating to novel cephalosporin intermediates

Country Status (13)

Country Link
US (1) US4525587A (enExample)
EP (1) EP0113568B1 (enExample)
JP (2) JPH0834744B2 (enExample)
KR (1) KR870000612B1 (enExample)
CA (1) CA1245629A (enExample)
DE (1) DE3381408D1 (enExample)
DK (1) DK164061C (enExample)
GB (1) GB2132616B (enExample)
GR (1) GR79485B (enExample)
HK (1) HK17089A (enExample)
HU (1) HU191911B (enExample)
IE (1) IE56485B1 (enExample)
IL (1) IL70470A (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4694079A (en) * 1985-07-29 1987-09-15 Bristol-Myers Company 3-propenyl cephalosporin solvates
AT387022B (de) * 1986-06-04 1988-11-25 Biochemie Gmbh Verfahren zur herstellung einer neuen kristallinen form eines cefalosporinderivats
US4734408A (en) * 1986-12-17 1988-03-29 Eli Lilly And Company Crystalline cephalosporin antibiotic salts and solvates
AT388736B (de) * 1987-10-08 1989-08-25 Biochemie Gmbh Neue stabile, kristalline formen des ceftazidime-t-butylesters und verfahren zu ihrer herstellung
GB8802622D0 (en) * 1988-02-05 1988-03-02 Glaxo Group Ltd Chemical compound
US5831085A (en) * 1997-01-16 1998-11-03 Lupin Laboratories Limited Process for manufacture of cephalosporin such as ceftazidime and intermediate thereof
CN106317081B (zh) * 2016-08-22 2018-08-31 山东罗欣药业集团恒欣药业有限公司 一种抗感染药物头孢他啶晶体化合物及其药物组合物
CN106397458A (zh) * 2016-09-23 2017-02-15 临沂草之美医药科技有限公司 一种治疗外科手术感染的药物头孢他啶晶体化合物
CN106432280A (zh) * 2016-09-23 2017-02-22 临沂草之美医药科技有限公司 一种治疗外科手术感染的药物头孢他啶晶体化合物
CN107722040A (zh) * 2017-10-10 2018-02-23 南京志坤环保科技有限公司 一种回收利用头孢他啶母液的膜分离方法及装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6056717B2 (ja) * 1977-09-27 1985-12-11 富山化学工業株式会社 セフアロスポリンのｎ，ｎ−ジメチルアセトアミド付加体及びその製法
AR229883A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
ZA807323B (en) * 1978-05-26 1981-02-25 Glaxo Group Ltd Cephalosporin antibiotics
BE883453A (fr) * 1979-05-25 1980-11-24 Glaxo Group Ltd Composes intermediaires pour la preparation de cephalosporines
EP0101148B1 (en) * 1982-04-29 1987-12-23 Glaxo Group Limited Thiazole derivative, process for its preparation and use in the preparation of beta-lactam antibiotics

Also Published As

Publication number Publication date
KR870000612B1 (ko) 1987-03-25
JPH069647A (ja) 1994-01-18
JPS59130889A (ja) 1984-07-27
DK584183D0 (da) 1983-12-19
GB2132616A (en) 1984-07-11
GB8333667D0 (en) 1984-01-25
HU191911B (en) 1987-04-28
DE3381408D1 (de) 1990-05-10
CA1245629A (en) 1988-11-29
KR840007013A (ko) 1984-12-04
DK164061B (da) 1992-05-04
DK164061C (da) 1992-09-28
IL70470A0 (en) 1984-03-30
IL70470A (en) 1988-04-29
GR79485B (enExample) 1984-10-30
EP0113568B1 (en) 1990-04-04
EP0113568A3 (en) 1985-07-31
GB2132616B (en) 1986-08-06
JPH0834744B2 (ja) 1996-03-29
US4525587A (en) 1985-06-25
DK584183A (da) 1984-06-28
IE833037L (en) 1984-06-27
HK17089A (en) 1989-03-03
EP0113568A2 (en) 1984-07-18
HUT34209A (en) 1985-02-28

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Legal Events

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MM4A Patent lapsed