IE55484B1 - Dithio compounds,pharmaceutical preparations containing them and their use - Google Patents
Dithio compounds,pharmaceutical preparations containing them and their useInfo
- Publication number
- IE55484B1 IE55484B1 IE1479/83A IE147983A IE55484B1 IE 55484 B1 IE55484 B1 IE 55484B1 IE 1479/83 A IE1479/83 A IE 1479/83A IE 147983 A IE147983 A IE 147983A IE 55484 B1 IE55484 B1 IE 55484B1
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- phenyl
- lower alkyl
- optionally substituted
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/08—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8218472 | 1982-06-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE831479L IE831479L (en) | 1983-12-25 |
| IE55484B1 true IE55484B1 (en) | 1990-09-26 |
Family
ID=10531279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1479/83A IE55484B1 (en) | 1982-06-25 | 1983-06-24 | Dithio compounds,pharmaceutical preparations containing them and their use |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US4818765A (OSRAM) |
| EP (1) | EP0099329B1 (OSRAM) |
| JP (1) | JPS5916887A (OSRAM) |
| KR (1) | KR900007319B1 (OSRAM) |
| AT (1) | ATE57927T1 (OSRAM) |
| AU (1) | AU566303B2 (OSRAM) |
| CA (1) | CA1239402A (OSRAM) |
| DD (1) | DD210908A5 (OSRAM) |
| DE (1) | DE3381964D1 (OSRAM) |
| DK (1) | DK292883A (OSRAM) |
| FI (1) | FI832291A7 (OSRAM) |
| GB (1) | GB2124211B (OSRAM) |
| GR (1) | GR79552B (OSRAM) |
| HU (1) | HU194862B (OSRAM) |
| IE (1) | IE55484B1 (OSRAM) |
| IL (1) | IL69056A (OSRAM) |
| NO (1) | NO832314L (OSRAM) |
| NZ (1) | NZ204700A (OSRAM) |
| PH (1) | PH25133A (OSRAM) |
| PT (1) | PT76934B (OSRAM) |
| ZA (1) | ZA834636B (OSRAM) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3586541T2 (de) * | 1985-05-31 | 1993-01-14 | Banyu Pharma Co Ltd | 1,3-dithiol-2-ylidenderivate. |
| ATE87920T1 (de) * | 1985-10-09 | 1993-04-15 | Nihon Nohyaku Co Ltd | Keten-s,s,-acetalderivate, verfahren zu ihrer herstellung und methode zur heilung von mykose unter verwendung dieser derivate. |
| JPS62158215A (ja) * | 1985-12-28 | 1987-07-14 | Nippon Nohyaku Co Ltd | 脂肪壊死症治療剤 |
| GB2188842A (en) * | 1986-02-05 | 1987-10-14 | Zyma Sa | Cyclic dithiols for treating pulmonary fibrosis |
| EP0234480A3 (en) * | 1986-02-21 | 1988-09-14 | Nihon Nohyaku Co., Ltd. | 1, 3-diketone derivatives and their use |
| CA1327361C (en) * | 1988-01-14 | 1994-03-01 | Nihon Nohyaku Co., Ltd. | Ketenedithioacetal derivative and processes for producing the same as well as a composition containing the same |
| KR920009818A (ko) * | 1990-11-26 | 1992-06-25 | 쯔무라 아끼라 | 신규 벤조디옥솔 유도체 및 이를 함유하는 간장해 개선제 |
| DE19645313A1 (de) | 1996-11-04 | 1998-05-07 | Basf Ag | Substituierte 3-Benzylpyrazole |
| US7498331B2 (en) * | 2003-11-06 | 2009-03-03 | United States Of America As Represented By The Secretary Of The Army | Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof |
| DE102013110740A1 (de) * | 2013-09-27 | 2015-04-02 | Karlsruher Institut für Technologie | Polymer-fixierte Dithiolan- bzw. Dithianderivate |
| DK3180335T3 (da) | 2014-08-11 | 2021-08-09 | Angion Biomedica Corp | Cytokrom-p450-inhibitorer og anvendelser deraf |
| CA2970819A1 (en) | 2014-12-31 | 2016-07-07 | Angion Biomedica Corp. | Methods and agents for treating disease |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3525751A (en) * | 1967-03-27 | 1970-08-25 | Syntex Corp | Hormonal diphenyl methylol and benzhydrylidene derivatives |
| FR1582882A (OSRAM) * | 1968-06-25 | 1969-10-10 | ||
| US3781281A (en) * | 1972-11-08 | 1973-12-25 | Du Pont | 2-arylidene-1,3-dithioles and preparation thereof from acethylenes,carbon disulfide,and aromatic aldehydes in the presence of aliphatic phosphines |
| GB1604739A (en) * | 1977-07-28 | 1981-12-16 | Yamanouchi Pharma Co Ltd | 7-methoxy-7-(1,3-dithietane-2-carboxamide) cephalosporanic acid derivatives |
| GB1604738A (en) * | 1977-07-28 | 1981-12-16 | Yamanouchi Pharma Co Ltd | 1,3-dithietane-2-carboxylic acid derivatives and the preparation thereof |
-
1983
- 1983-06-13 GB GB08316086A patent/GB2124211B/en not_active Expired
- 1983-06-20 DE DE8383810266T patent/DE3381964D1/de not_active Expired - Lifetime
- 1983-06-20 EP EP83810266A patent/EP0099329B1/en not_active Expired - Lifetime
- 1983-06-20 AT AT83810266T patent/ATE57927T1/de not_active IP Right Cessation
- 1983-06-22 FI FI832291A patent/FI832291A7/fi not_active Application Discontinuation
- 1983-06-23 IL IL69056A patent/IL69056A/xx unknown
- 1983-06-23 CA CA000431073A patent/CA1239402A/en not_active Expired
- 1983-06-23 PH PH29106A patent/PH25133A/en unknown
- 1983-06-24 NZ NZ204700A patent/NZ204700A/en unknown
- 1983-06-24 DK DK292883A patent/DK292883A/da not_active Application Discontinuation
- 1983-06-24 AU AU16261/83A patent/AU566303B2/en not_active Ceased
- 1983-06-24 ZA ZA834636A patent/ZA834636B/xx unknown
- 1983-06-24 IE IE1479/83A patent/IE55484B1/en unknown
- 1983-06-24 PT PT76934A patent/PT76934B/pt unknown
- 1983-06-24 HU HU832298A patent/HU194862B/hu unknown
- 1983-06-24 NO NO832314A patent/NO832314L/no unknown
- 1983-06-24 GR GR71777A patent/GR79552B/el unknown
- 1983-06-25 JP JP58113672A patent/JPS5916887A/ja active Pending
- 1983-06-25 KR KR1019830002905A patent/KR900007319B1/ko not_active Expired
- 1983-06-27 DD DD83252414A patent/DD210908A5/de not_active IP Right Cessation
-
1987
- 1987-02-11 US US07/013,164 patent/US4818765A/en not_active Expired - Fee Related
-
1988
- 1988-11-14 US US07/271,125 patent/US4946861A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU566303B2 (en) | 1987-10-15 |
| DK292883A (da) | 1983-12-26 |
| EP0099329B1 (en) | 1990-10-31 |
| EP0099329A1 (en) | 1984-01-25 |
| FI832291L (fi) | 1983-12-26 |
| CA1239402A (en) | 1988-07-19 |
| JPS5916887A (ja) | 1984-01-28 |
| PH25133A (en) | 1991-02-19 |
| NO832314L (no) | 1983-12-27 |
| KR840005126A (ko) | 1984-11-03 |
| NZ204700A (en) | 1986-03-14 |
| GB2124211A (en) | 1984-02-15 |
| DK292883D0 (da) | 1983-06-24 |
| US4818765A (en) | 1989-04-04 |
| IL69056A (en) | 1987-12-31 |
| GR79552B (OSRAM) | 1984-10-30 |
| ZA834636B (en) | 1984-03-28 |
| US4946861A (en) | 1990-08-07 |
| IL69056A0 (en) | 1983-10-31 |
| FI832291A0 (fi) | 1983-06-22 |
| FI832291A7 (fi) | 1983-12-26 |
| ATE57927T1 (de) | 1990-11-15 |
| PT76934A (en) | 1983-07-01 |
| IE831479L (en) | 1983-12-25 |
| HU194862B (en) | 1988-03-28 |
| DD210908A5 (de) | 1984-06-27 |
| PT76934B (en) | 1986-04-21 |
| AU1626183A (en) | 1984-01-05 |
| GB2124211B (en) | 1985-12-24 |
| DE3381964D1 (de) | 1990-12-06 |
| GB8316086D0 (en) | 1983-07-20 |
| KR900007319B1 (ko) | 1990-10-08 |
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