IE51273B1 - Modified glucosaminoglycans having antilipemic activity and essentially devoid of anticoagulant activity - Google Patents

Modified glucosaminoglycans having antilipemic activity and essentially devoid of anticoagulant activity

Info

Publication number
IE51273B1
IE51273B1 IE1341/81A IE134181A IE51273B1 IE 51273 B1 IE51273 B1 IE 51273B1 IE 1341/81 A IE1341/81 A IE 1341/81A IE 134181 A IE134181 A IE 134181A IE 51273 B1 IE51273 B1 IE 51273B1
Authority
IE
Ireland
Prior art keywords
heparin
activity
derivative
succinyl
product
Prior art date
Application number
IE1341/81A
Other languages
English (en)
Other versions
IE811341L (en
Original Assignee
Italfarmaco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco Spa filed Critical Italfarmaco Spa
Publication of IE811341L publication Critical patent/IE811341L/xx
Publication of IE51273B1 publication Critical patent/IE51273B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/02—Resin hair settings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/04—Dandruff

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
IE1341/81A 1980-06-18 1981-06-17 Modified glucosaminoglycans having antilipemic activity and essentially devoid of anticoagulant activity IE51273B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22851/80A IT1140999B (it) 1980-06-18 1980-06-18 Glicosaminoglicani modificati dotati di attivita' antilipemica e privi di attivita' anticoagulante

Publications (2)

Publication Number Publication Date
IE811341L IE811341L (en) 1981-12-18
IE51273B1 true IE51273B1 (en) 1986-11-26

Family

ID=11201157

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1341/81A IE51273B1 (en) 1980-06-18 1981-06-17 Modified glucosaminoglycans having antilipemic activity and essentially devoid of anticoagulant activity

Country Status (21)

Country Link
US (1) US4459289A (instruction)
JP (1) JPS5952164B2 (instruction)
AR (1) AR227317A1 (instruction)
AU (1) AU531118B2 (instruction)
BE (1) BE889275A (instruction)
DE (1) DE3123806A1 (instruction)
DK (1) DK267681A (instruction)
ES (1) ES503199A0 (instruction)
FI (1) FI811832A7 (instruction)
FR (1) FR2485019A1 (instruction)
GB (1) GB2078768B (instruction)
GR (1) GR75703B (instruction)
IE (1) IE51273B1 (instruction)
IT (1) IT1140999B (instruction)
LU (1) LU83435A1 (instruction)
NL (1) NL8102947A (instruction)
NO (1) NO812055L (instruction)
PH (1) PH17676A (instruction)
PT (1) PT73214B (instruction)
SE (1) SE8103677L (instruction)
ZA (1) ZA814047B (instruction)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1169888B (it) * 1983-10-25 1987-06-03 Italfarmaco Spa Glicosaminoglicani modificati dotati di attivita' antitrombotica
IT1188184B (it) * 1985-08-14 1988-01-07 Texcontor Ets Sali ammonici quaternari di polisaccaridi ad attivita' ipocolesterolemizzante
US4855139A (en) * 1987-01-20 1989-08-08 Med. Fab (Lafayette), Inc. Fungicidally active cellulosic textile compositions, or articles of manufacture
US5063210A (en) * 1989-04-20 1991-11-05 Lange Iii Louis G Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption
US5017565A (en) * 1989-04-20 1991-05-21 Lange Iii Louis G Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase
US5484777A (en) * 1989-04-20 1996-01-16 Lange, Iii; Louis G. Pancreatic cholesterol esterase inhibitor
US5419913A (en) * 1992-03-05 1995-05-30 Podell; Howard I. Adhesive bandages, wound dressings, sutures, drapes, orthodontic rubber bands, toothbrushes, and the like
ZA947572B (en) * 1993-09-29 1995-09-28 Hampton Roads Medical College Contraceptive compositions
US6242042B1 (en) 1998-09-14 2001-06-05 Lrc Products Ltd. Aqueous coating composition and method
ATE356515T1 (de) * 2003-09-03 2007-03-15 Research In Motion Ltd Verfahren und vorrichtungen zur anzeige eines heimnetzwerknamens
US8343473B2 (en) 2005-08-24 2013-01-01 Purdue Research Foundation Hydrophilized antimicrobial polymers
US20070048249A1 (en) 2005-08-24 2007-03-01 Purdue Research Foundation Hydrophilized bactericidal polymers
WO2018222622A1 (en) 2017-05-27 2018-12-06 Poly Group LLC Dispersible antimicrobial complex and coatings therefrom
WO2018232417A1 (en) 2017-06-16 2018-12-20 Poly Group LLC Polymeric antimicrobial surfactant

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US26510A (en) * 1859-12-20 andrews
US3118816A (en) * 1962-04-03 1964-01-21 Abbott Lab N-succinyl heparin and process
US3320080A (en) 1964-06-05 1967-05-16 Nat Starch Chem Corp Water resistant paper coating compositions
FR2036453A5 (en) * 1969-03-14 1970-12-24 Henry Michel Cosmetic preparations additive
US3567420A (en) * 1969-04-08 1971-03-02 Shell Oil Co Use of certain polyamines as antimicrobial agents
US4080346A (en) * 1970-07-27 1978-03-21 Polaroid Corporation Novel graft copolymers having vinylbenzyl ammonium halide residues
US4144326A (en) * 1975-05-19 1979-03-13 American Cyanamid Company Oil free, water-soluble, clear creme rinse for hair
US4035146A (en) * 1975-10-20 1977-07-12 Schwarz Services International Ltd. Binding of antimicrobial compounds to a hydroxyl containing substrate with cyanuric chloride
US4131576A (en) * 1977-12-15 1978-12-26 National Starch And Chemical Corporation Process for the preparation of graft copolymers of a water soluble monomer and polysaccharide employing a two-phase reaction system
US4155885A (en) * 1978-04-28 1979-05-22 Merck & Co., Inc. Amphoteric graft copolymers of xanthomonas hydrophilic colloid and partially N-aminomethylated acrylamide
JPS6042762B2 (ja) * 1978-09-07 1985-09-25 ライオン株式会社 カチオン化多糖類を含有する化粧料
JPS6042763B2 (ja) * 1978-09-25 1985-09-25 ライオン株式会社 親和性の良好な化粧料
US4285973A (en) * 1979-07-20 1981-08-25 Alberto-Culver Company Liquid composition for application to the skin

Also Published As

Publication number Publication date
ES8203391A1 (es) 1982-04-01
GB2078768A (en) 1982-01-13
DK267681A (da) 1981-12-19
SE8103677L (sv) 1981-12-19
IT8022851A0 (it) 1980-06-18
LU83435A1 (fr) 1981-10-29
NO812055L (no) 1981-12-21
NL8102947A (nl) 1982-01-18
IE811341L (en) 1981-12-18
PH17676A (en) 1984-11-02
US4459289A (en) 1984-07-10
JPS57102903A (en) 1982-06-26
BE889275A (nl) 1981-10-16
AU531118B2 (en) 1983-08-11
AR227317A1 (es) 1982-10-15
ZA814047B (en) 1982-06-30
IT1140999B (it) 1986-10-10
ES503199A0 (es) 1982-04-01
FR2485019A1 (fr) 1981-12-24
GB2078768B (en) 1983-10-05
FR2485019B1 (instruction) 1984-12-07
AU7187381A (en) 1981-12-24
FI811832L (fi) 1981-12-19
JPS5952164B2 (ja) 1984-12-18
FI811832A7 (fi) 1981-12-19
PT73214A (en) 1981-07-01
DE3123806A1 (de) 1982-03-18
GR75703B (instruction) 1984-08-02
PT73214B (en) 1982-07-16

Similar Documents

Publication Publication Date Title
EP0394971A1 (en) Oligosaccharide-containing inhibitors of endothelial cell growth and angiogenesis
EP1268558B1 (en) Derivatives of partially desulphated glycosaminoglycans endowed with antiangiogenic activity and devoid of anticoagulating effect
IE51273B1 (en) Modified glucosaminoglycans having antilipemic activity and essentially devoid of anticoagulant activity
US5010063A (en) Heparin derivatives and process for their preparation
US5008253A (en) Sulfoamino derivatives of chondroitin sulfates of dermatan sulfate and of hyaluronic acid and their pharmacological properties
JP5001989B2 (ja) ケラタン硫酸オリゴ糖画分の製造法
Nordén et al. A mannose-containing trisaccharide isolated from urines of three patients with mannosidosis
US9475888B2 (en) Non anti-coagulative glycosaminoglycans comprising repeating disaccharide unit and their medical use
JPH04503950A (ja) 平滑筋細胞増殖のインヒビターとしてのヘパリン断片
DE68921633T2 (de) Oligosaccharide mit antiatherosclerotischer wirkung.
JPH0629282B2 (ja) 解重合及び超硫酸化ヘパリン、その製造方法並びに製薬組成物
KR20010030803A (ko) 신규 글리코사미노글리칸 및 이를 함유하는 의약 조성물
DE3422518A1 (de) Heparin-derivate, verfahren zu ihrer herstellung, diese enthaltende arzneimittel und ihre verwendung bei der behandlung von fettstoffwechselstoerungen
DE69531945T2 (de) Verfahren zur herstellung von desulfatiertem polysaccharid und desulfatiertem heparin
Mathews Chondroitin sulphate and collagen in inherited skeletal defects of chickens
JPH0273801A (ja) 選択的にｏ―アシル化されたグリコサミノグリカン
DE69023708T2 (de) Anti-hiv-heilmittel.
EP0408770B1 (en) New sulfated polysaccharide, pharmaceutically acceptable salts thereof, preparation thereof, and drug containing the same as active ingredient
Abad‐Rodríguez et al. Control of glial number: purification from mammalian brain extracts of an inhibitor of astrocyte division
US6329351B1 (en) Semi-synthetic sulphaminoheparosansulphates having high anti-metastatic activity and reduced haemorrhagic risk
EP0618215B1 (en) Oligosaccharides used for inhibiting the mitosis of astrocytes and tumoral cells of the nervous system, and methods for obtaining them
DE69113437T2 (de) Therapeutische Mittel für diabetisches Gangrän.
DE1792196A1 (de) Verfahren zur Stabilisierung eines Proteins
JPH03185001A (ja) ヘパリンのｎ―アセチル化物及びその製造方法
EP0351809A2 (en) Blood anticoagulant