ES8203391A1 - Procedimiento para la preparacion de un derivado succiniladode la heparina desulfatada - Google Patents
Procedimiento para la preparacion de un derivado succiniladode la heparina desulfatadaInfo
- Publication number
- ES8203391A1 ES8203391A1 ES503199A ES503199A ES8203391A1 ES 8203391 A1 ES8203391 A1 ES 8203391A1 ES 503199 A ES503199 A ES 503199A ES 503199 A ES503199 A ES 503199A ES 8203391 A1 ES8203391 A1 ES 8203391A1
- Authority
- ES
- Spain
- Prior art keywords
- copolymers
- bactericidal activity
- preparation
- pharmaceutical compositions
- monomeric unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/02—Resin hair settings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/04—Dandruff
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE UN DERIVADO SUCCILINADO DE LA HEPARINA. CONSISTE EN HIDROLIZAR LA HEPARINA REACTIVAMENTE DE NORMALIDAD AL MIENOS IGUAL A 0,1 N. EL PRODUCTO OBTENIDO SE SUCCINILA POR REACCION CON ANHIDRIDO SUCCINICO A VALORES DE PH MAYORES QUE 7. LA TEMPERATURA DE REACCION OSCILA ENTRE 70 Y 100 C EN UN TIEMPO MAYOR DE TRES HORAS. EL TRATAMIENTO HIDROLICO SE EFECTUA EN ACIDOS FUERTES DE NORMALIDAD IGUAL O MAYOR DE 0,5 N. LA PROPORCION PONDERABLE EN QUE SE VERIFICA LA REACCION ENTRE EL ACIDO SUCCINICO Y LA HEPARINA HIDROLIZADA SE HALLA ENTRE 1 : 1 Y 5 : 1.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22851/80A IT1140999B (it) | 1980-06-18 | 1980-06-18 | Glicosaminoglicani modificati dotati di attivita' antilipemica e privi di attivita' anticoagulante |
Publications (2)
Publication Number | Publication Date |
---|---|
ES503199A0 ES503199A0 (es) | 1982-04-01 |
ES8203391A1 true ES8203391A1 (es) | 1982-04-01 |
Family
ID=11201157
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES503199A Expired ES8203391A1 (es) | 1980-06-18 | 1981-06-17 | Procedimiento para la preparacion de un derivado succiniladode la heparina desulfatada |
Country Status (21)
Country | Link |
---|---|
US (1) | US4459289A (es) |
JP (1) | JPS5952164B2 (es) |
AR (1) | AR227317A1 (es) |
AU (1) | AU531118B2 (es) |
BE (1) | BE889275A (es) |
DE (1) | DE3123806A1 (es) |
DK (1) | DK267681A (es) |
ES (1) | ES8203391A1 (es) |
FI (1) | FI811832L (es) |
FR (1) | FR2485019A1 (es) |
GB (1) | GB2078768B (es) |
GR (1) | GR75703B (es) |
IE (1) | IE51273B1 (es) |
IT (1) | IT1140999B (es) |
LU (1) | LU83435A1 (es) |
NL (1) | NL8102947A (es) |
NO (1) | NO812055L (es) |
PH (1) | PH17676A (es) |
PT (1) | PT73214B (es) |
SE (1) | SE8103677L (es) |
ZA (1) | ZA814047B (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1169888B (it) * | 1983-10-25 | 1987-06-03 | Italfarmaco Spa | Glicosaminoglicani modificati dotati di attivita' antitrombotica |
JPS61250374A (ja) * | 1985-04-29 | 1986-11-07 | Honda Motor Co Ltd | サイドブランチ型消音装置 |
IT1188184B (it) * | 1985-08-14 | 1988-01-07 | Texcontor Ets | Sali ammonici quaternari di polisaccaridi ad attivita' ipocolesterolemizzante |
US4855139A (en) * | 1987-01-20 | 1989-08-08 | Med. Fab (Lafayette), Inc. | Fungicidally active cellulosic textile compositions, or articles of manufacture |
US5017565A (en) * | 1989-04-20 | 1991-05-21 | Lange Iii Louis G | Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase |
US5063210A (en) * | 1989-04-20 | 1991-11-05 | Lange Iii Louis G | Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption |
US5484777A (en) * | 1989-04-20 | 1996-01-16 | Lange, Iii; Louis G. | Pancreatic cholesterol esterase inhibitor |
US5419913A (en) * | 1992-03-05 | 1995-05-30 | Podell; Howard I. | Adhesive bandages, wound dressings, sutures, drapes, orthodontic rubber bands, toothbrushes, and the like |
ZA947572B (en) * | 1993-09-29 | 1995-09-28 | Hampton Roads Medical College | Contraceptive compositions |
US6242042B1 (en) | 1998-09-14 | 2001-06-05 | Lrc Products Ltd. | Aqueous coating composition and method |
DE60312326T2 (de) * | 2003-09-03 | 2007-11-08 | Research In Motion Ltd., Waterloo | Verfahren und Vorrichtungen zur Anzeige eines Heimnetzwerknamens |
US8343473B2 (en) | 2005-08-24 | 2013-01-01 | Purdue Research Foundation | Hydrophilized antimicrobial polymers |
US20070048249A1 (en) | 2005-08-24 | 2007-03-01 | Purdue Research Foundation | Hydrophilized bactericidal polymers |
US20180340046A1 (en) | 2017-05-27 | 2018-11-29 | Poly Group LLC | Dispersible antimicrobial complex and coatings therefrom |
WO2018232417A1 (en) | 2017-06-16 | 2018-12-20 | Poly Group LLC | Polymeric antimicrobial surfactant |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US26510A (en) * | 1859-12-20 | andrews | ||
US3118816A (en) * | 1962-04-03 | 1964-01-21 | Abbott Lab | N-succinyl heparin and process |
US3320080A (en) | 1964-06-05 | 1967-05-16 | Nat Starch Chem Corp | Water resistant paper coating compositions |
FR2036453A5 (en) * | 1969-03-14 | 1970-12-24 | Henry Michel | Cosmetic preparations additive |
US3567420A (en) * | 1969-04-08 | 1971-03-02 | Shell Oil Co | Use of certain polyamines as antimicrobial agents |
US4080346A (en) * | 1970-07-27 | 1978-03-21 | Polaroid Corporation | Novel graft copolymers having vinylbenzyl ammonium halide residues |
US4144326A (en) * | 1975-05-19 | 1979-03-13 | American Cyanamid Company | Oil free, water-soluble, clear creme rinse for hair |
US4035146A (en) * | 1975-10-20 | 1977-07-12 | Schwarz Services International Ltd. | Binding of antimicrobial compounds to a hydroxyl containing substrate with cyanuric chloride |
US4131576A (en) * | 1977-12-15 | 1978-12-26 | National Starch And Chemical Corporation | Process for the preparation of graft copolymers of a water soluble monomer and polysaccharide employing a two-phase reaction system |
US4155885A (en) * | 1978-04-28 | 1979-05-22 | Merck & Co., Inc. | Amphoteric graft copolymers of xanthomonas hydrophilic colloid and partially N-aminomethylated acrylamide |
JPS6042762B2 (ja) * | 1978-09-07 | 1985-09-25 | ライオン株式会社 | カチオン化多糖類を含有する化粧料 |
JPS6042763B2 (ja) * | 1978-09-25 | 1985-09-25 | ライオン株式会社 | 親和性の良好な化粧料 |
US4285973A (en) * | 1979-07-20 | 1981-08-25 | Alberto-Culver Company | Liquid composition for application to the skin |
-
1980
- 1980-06-18 IT IT22851/80A patent/IT1140999B/it active
-
1981
- 1981-06-11 SE SE8103677A patent/SE8103677L/xx not_active Application Discontinuation
- 1981-06-12 FI FI811832A patent/FI811832L/fi not_active Application Discontinuation
- 1981-06-15 GB GB8118383A patent/GB2078768B/en not_active Expired
- 1981-06-16 AU AU71873/81A patent/AU531118B2/en not_active Ceased
- 1981-06-16 DE DE19813123806 patent/DE3123806A1/de not_active Ceased
- 1981-06-16 ZA ZA814047A patent/ZA814047B/xx unknown
- 1981-06-17 GR GR65251A patent/GR75703B/el unknown
- 1981-06-17 PT PT73214A patent/PT73214B/pt unknown
- 1981-06-17 ES ES503199A patent/ES8203391A1/es not_active Expired
- 1981-06-17 NO NO812055A patent/NO812055L/no unknown
- 1981-06-17 IE IE1341/81A patent/IE51273B1/en unknown
- 1981-06-17 LU LU83435A patent/LU83435A1/fr unknown
- 1981-06-18 FR FR8112070A patent/FR2485019A1/fr active Granted
- 1981-06-18 JP JP56095156A patent/JPS5952164B2/ja not_active Expired
- 1981-06-18 BE BE2/59221A patent/BE889275A/nl not_active IP Right Cessation
- 1981-06-18 DK DK267681A patent/DK267681A/da not_active Application Discontinuation
- 1981-06-18 PH PH25774A patent/PH17676A/en unknown
- 1981-06-18 NL NL8102947A patent/NL8102947A/nl not_active Application Discontinuation
- 1981-06-19 AR AR285753A patent/AR227317A1/es active
-
1982
- 1982-01-04 US US06/336,964 patent/US4459289A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPS57102903A (en) | 1982-06-26 |
DK267681A (da) | 1981-12-19 |
IE51273B1 (en) | 1986-11-26 |
GB2078768B (en) | 1983-10-05 |
IT8022851A0 (it) | 1980-06-18 |
LU83435A1 (fr) | 1981-10-29 |
FI811832L (fi) | 1981-12-19 |
FR2485019A1 (fr) | 1981-12-24 |
PH17676A (en) | 1984-11-02 |
ES503199A0 (es) | 1982-04-01 |
PT73214B (en) | 1982-07-16 |
US4459289A (en) | 1984-07-10 |
AU7187381A (en) | 1981-12-24 |
FR2485019B1 (es) | 1984-12-07 |
AR227317A1 (es) | 1982-10-15 |
IT1140999B (it) | 1986-10-10 |
DE3123806A1 (de) | 1982-03-18 |
GB2078768A (en) | 1982-01-13 |
AU531118B2 (en) | 1983-08-11 |
NL8102947A (nl) | 1982-01-18 |
JPS5952164B2 (ja) | 1984-12-18 |
NO812055L (no) | 1981-12-21 |
PT73214A (en) | 1981-07-01 |
BE889275A (nl) | 1981-10-16 |
IE811341L (en) | 1981-12-18 |
SE8103677L (sv) | 1981-12-19 |
ZA814047B (en) | 1982-06-30 |
GR75703B (es) | 1984-08-02 |
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