IE49395B1 - New cephalosporin derivatives,their production and use as antimicrobial agents - Google Patents

New cephalosporin derivatives,their production and use as antimicrobial agents

Info

Publication number
IE49395B1
IE49395B1 IE284/80A IE28480A IE49395B1 IE 49395 B1 IE49395 B1 IE 49395B1 IE 284/80 A IE284/80 A IE 284/80A IE 28480 A IE28480 A IE 28480A IE 49395 B1 IE49395 B1 IE 49395B1
Authority
IE
Ireland
Prior art keywords
pyrazolyl
compound
acid
syn
formula
Prior art date
Application number
IE284/80A
Other languages
English (en)
Other versions
IE800284L (en
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH154579A external-priority patent/CH641810A5/de
Priority claimed from CH17480A external-priority patent/CH645378A5/de
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Priority to IE1624/84A priority Critical patent/IE49396B1/en
Publication of IE800284L publication Critical patent/IE800284L/xx
Publication of IE49395B1 publication Critical patent/IE49395B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • C07D231/40Acylated on said nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IE284/80A 1979-02-16 1980-02-14 New cephalosporin derivatives,their production and use as antimicrobial agents IE49395B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IE1624/84A IE49396B1 (en) 1979-02-16 1980-02-14 Oximinoacetic acid derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH154579A CH641810A5 (en) 1979-02-16 1979-02-16 Acetamidocephalosporanic acid derivatives, process for their preparation and pharmaceutical forms which contain them
CH17480A CH645378A5 (en) 1980-01-10 1980-01-10 Acetamidocephalosporanic acid derivatives, process for their preparation and pharmaceutical forms which contain them

Publications (2)

Publication Number Publication Date
IE800284L IE800284L (en) 1980-08-16
IE49395B1 true IE49395B1 (en) 1985-10-02

Family

ID=25683752

Family Applications (1)

Application Number Title Priority Date Filing Date
IE284/80A IE49395B1 (en) 1979-02-16 1980-02-14 New cephalosporin derivatives,their production and use as antimicrobial agents

Country Status (19)

Country Link
US (1) US4477448A (OSRAM)
AT (1) AT374806B (OSRAM)
CA (1) CA1161032A (OSRAM)
DE (1) DE3005012A1 (OSRAM)
DK (1) DK53780A (OSRAM)
ES (2) ES488651A0 (OSRAM)
FI (1) FI800381A7 (OSRAM)
FR (1) FR2449093A1 (OSRAM)
GB (2) GB2046734B (OSRAM)
IE (1) IE49395B1 (OSRAM)
IL (1) IL59391A (OSRAM)
IT (1) IT8047922A0 (OSRAM)
MY (1) MY8500128A (OSRAM)
NL (1) NL8000894A (OSRAM)
NZ (1) NZ192873A (OSRAM)
PH (1) PH17926A (OSRAM)
PT (1) PT70834A (OSRAM)
SE (2) SE8000982L (OSRAM)
YU (1) YU40280A (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3165922D1 (en) * 1980-03-28 1984-10-18 Biochemie Gmbh New process for the production of cephalosporin antibiotics, and novel intermediates used in such process and their production
CH648038A5 (de) * 1981-01-19 1985-02-28 Sandoz Ag 7-((carboxymethoxyimino)-1h-pyrazol-3-yl-acetyl)amino-3-desacetoxy-3-(1-methyl-1h-tetrazol-5-yl-thio)cephalosporansaeure und salze, verfahren zur herstellung und verwendung.
GB2125033B (en) * 1982-07-23 1985-08-29 Servipharm Ltd Cephalosporins
US4698338A (en) * 1986-02-19 1987-10-06 Eli Lilly And Company 7[2-(2-aminothiazol-4-yl)-2-benzyloximino]acetamido-3[4-alkyl-5-oxo-6-hydroxy-3,4-dihydro-1,2,4-triazin-3-yl]thiomethyl cephalosporins
US5688964A (en) * 1996-02-13 1997-11-18 Eastman Kodak Company Process for preparing a acylhyrazino pyrazole derivative
KR100770419B1 (ko) * 1999-09-24 2007-10-26 니혼노야쿠가부시키가이샤 살충, 살진드기제
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
CA2789262C (en) 2005-04-28 2016-10-04 Proteus Digital Health, Inc. Pharma-informatics system
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
CN110075069A (zh) 2009-05-06 2019-08-02 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024137A (en) * 1971-05-14 1977-05-17 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(phenyl- or naphthylacetamido)] cephalosporins

Also Published As

Publication number Publication date
PT70834A (en) 1980-03-01
YU40280A (en) 1983-06-30
ES8102134A1 (es) 1980-12-16
FR2449093A1 (fr) 1980-09-12
ES488651A0 (es) 1980-12-16
GB2046734A (en) 1980-11-19
GB8309730D0 (en) 1983-05-18
SE8000982L (sv) 1980-08-17
ATA78780A (de) 1983-10-15
FR2449093B1 (OSRAM) 1983-07-29
IT8047922A0 (it) 1980-02-15
NZ192873A (en) 1984-07-31
SE8500589D0 (sv) 1985-02-08
CA1161032A (en) 1984-01-24
GB2117774A (en) 1983-10-19
MY8500128A (en) 1985-12-31
DE3005012A1 (de) 1980-11-27
US4477448A (en) 1984-10-16
PH17926A (en) 1985-01-31
NL8000894A (nl) 1980-08-19
AT374806B (de) 1984-06-12
IE800284L (en) 1980-08-16
IL59391A (en) 1983-05-15
GB2117774B (en) 1984-03-21
ES497002A0 (es) 1982-04-01
ES8203848A1 (es) 1982-04-01
IL59391A0 (en) 1980-05-30
DK53780A (da) 1980-08-17
FI800381A7 (fi) 1981-01-01
GB2046734B (en) 1983-09-01

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