IE46983B1 - Fluorinated amino acids - Google Patents

Fluorinated amino acids

Info

Publication number
IE46983B1
IE46983B1 IE1078/78A IE107878A IE46983B1 IE 46983 B1 IE46983 B1 IE 46983B1 IE 1078/78 A IE1078/78 A IE 1078/78A IE 107878 A IE107878 A IE 107878A IE 46983 B1 IE46983 B1 IE 46983B1
Authority
IE
Ireland
Prior art keywords
compound
formula
cooh
fluoromethyl
isomer configuration
Prior art date
Application number
IE1078/78A
Other languages
English (en)
Other versions
IE781078L (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/802,391 external-priority patent/US4325961A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IE781078L publication Critical patent/IE781078L/xx
Publication of IE46983B1 publication Critical patent/IE46983B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
IE1078/78A 1977-06-01 1978-05-30 Fluorinated amino acids IE46983B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80238977A 1977-06-01 1977-06-01
US05/802,391 US4325961A (en) 1977-06-01 1977-06-01 Fluorinated amino acids

Publications (2)

Publication Number Publication Date
IE781078L IE781078L (en) 1978-12-01
IE46983B1 true IE46983B1 (en) 1983-11-16

Family

ID=27122442

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1078/78A IE46983B1 (en) 1977-06-01 1978-05-30 Fluorinated amino acids

Country Status (26)

Country Link
JP (1) JPS5416423A (cg-RX-API-DMAC7.html)
AR (1) AR223463A1 (cg-RX-API-DMAC7.html)
AT (1) AT360509B (cg-RX-API-DMAC7.html)
AU (1) AU518479B2 (cg-RX-API-DMAC7.html)
CA (1) CA1120040A (cg-RX-API-DMAC7.html)
CH (1) CH639639A5 (cg-RX-API-DMAC7.html)
DD (1) DD138651A5 (cg-RX-API-DMAC7.html)
DE (1) DE2824116A1 (cg-RX-API-DMAC7.html)
DK (1) DK149841C (cg-RX-API-DMAC7.html)
ES (1) ES470296A1 (cg-RX-API-DMAC7.html)
FI (1) FI66840C (cg-RX-API-DMAC7.html)
FR (1) FR2392958A1 (cg-RX-API-DMAC7.html)
GB (1) GB1602525A (cg-RX-API-DMAC7.html)
GR (1) GR64495B (cg-RX-API-DMAC7.html)
HK (1) HK18184A (cg-RX-API-DMAC7.html)
HU (1) HU181911B (cg-RX-API-DMAC7.html)
IE (1) IE46983B1 (cg-RX-API-DMAC7.html)
IT (1) IT1104709B (cg-RX-API-DMAC7.html)
LU (1) LU79750A1 (cg-RX-API-DMAC7.html)
NL (1) NL190485C (cg-RX-API-DMAC7.html)
NO (1) NO147382C (cg-RX-API-DMAC7.html)
NZ (1) NZ187377A (cg-RX-API-DMAC7.html)
PL (1) PL115731B1 (cg-RX-API-DMAC7.html)
PT (1) PT68102B (cg-RX-API-DMAC7.html)
SE (1) SE7806440L (cg-RX-API-DMAC7.html)
YU (1) YU129178A (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1091661A (en) * 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
IL59481A0 (en) * 1977-07-11 1980-05-30 Merrell Toraude & Co -halomethyl amino acids
ZA783273B (en) * 1977-07-11 1979-06-27 Merrell Toraude & Co A-halomethyl amino acids
US4315095A (en) * 1977-07-28 1982-02-09 Merrell Toraude Et Compagnie α-Halomethyl derivatives of amino acids
DE2965364D1 (en) * 1978-07-24 1983-06-16 Merck & Co Inc Alpha-difluoromethyl amino acids and pharmaceutical composition containing the same
IE49522B1 (en) * 1979-04-26 1985-10-16 Merrell Toraude & Co Alpha-halomethylaminoacids
NZ194347A (en) * 1979-07-26 1982-11-23 Merrell Toraude & Co Fluorinated alkenylamines intermediate alkenyl fluorinated methyl ketimine magnesium halides and preparation of certain amino alkanoic acids
ZA813018B (en) * 1980-05-09 1982-05-26 Merrell Toraude & Co Fluoromethylated tyrosine methyl ester
CA1174603A (en) * 1980-06-16 1984-09-18 Albert Sjoerdsma Method of inhibiting the growth of protozoa
US4421767A (en) * 1981-06-01 1983-12-20 Merrell Toraude Et Compagnie Compounds and methods for treating depression
GB9325368D0 (en) * 1993-12-10 1994-02-16 Univ Bristol Organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046300A (en) * 1960-10-21 1962-07-24 Merck & Co Inc alpha-trifluoromethyloxyphenylalanines

Also Published As

Publication number Publication date
FR2392958A1 (fr) 1978-12-29
NZ187377A (en) 1981-05-15
CA1120040A (en) 1982-03-16
GR64495B (en) 1980-03-31
AR223463A1 (es) 1981-08-31
JPS5416423A (en) 1979-02-07
DE2824116C2 (cg-RX-API-DMAC7.html) 1989-04-27
NL190485B (nl) 1993-10-18
DK237978A (da) 1979-01-19
PT68102B (en) 1982-06-08
FR2392958B1 (cg-RX-API-DMAC7.html) 1980-10-24
DK149841C (da) 1987-04-21
AU518479B2 (en) 1981-10-01
PL115731B1 (en) 1981-04-30
PT68102A (en) 1978-06-01
HK18184A (en) 1984-03-09
NL7805981A (nl) 1978-12-05
FI66840B (fi) 1984-08-31
AT360509B (de) 1981-01-12
JPS641474B2 (cg-RX-API-DMAC7.html) 1989-01-11
ATA393278A (de) 1980-06-15
LU79750A1 (fr) 1979-02-02
DE2824116A1 (de) 1978-12-14
YU129178A (en) 1983-01-21
FI781674A7 (fi) 1978-12-02
CH639639A5 (en) 1983-11-30
AU3658678A (en) 1979-12-06
GB1602525A (en) 1981-11-11
NO147382C (no) 1983-03-30
FI66840C (fi) 1984-12-10
NO781892L (no) 1978-12-04
DK149841B (da) 1986-10-13
SE7806440L (sv) 1978-12-02
NL190485C (nl) 1994-03-16
ES470296A1 (es) 1979-09-16
IT7849637A0 (it) 1978-05-31
HU181911B (en) 1983-11-28
IE781078L (en) 1978-12-01
NO147382B (no) 1982-12-20
DD138651A5 (de) 1979-11-14
IT1104709B (it) 1985-10-28
PL207242A1 (pl) 1979-04-23

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