IE46761B1 - Benzazepines - Google Patents

Benzazepines

Info

Publication number
IE46761B1
IE46761B1 IE111/78A IE11178A IE46761B1 IE 46761 B1 IE46761 B1 IE 46761B1 IE 111/78 A IE111/78 A IE 111/78A IE 11178 A IE11178 A IE 11178A IE 46761 B1 IE46761 B1 IE 46761B1
Authority
IE
Ireland
Prior art keywords
compound
hydrogen
methylthio
methyl
carbons
Prior art date
Application number
IE111/78A
Other languages
English (en)
Other versions
IE780111L (en
Inventor
Jooji Hooruden Kenesu
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of IE780111L publication Critical patent/IE780111L/xx
Publication of IE46761B1 publication Critical patent/IE46761B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/04Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IE111/78A 1977-01-19 1978-01-18 Benzazepines IE46761B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76050077A 1977-01-19 1977-01-19

Publications (2)

Publication Number Publication Date
IE780111L IE780111L (en) 1978-07-19
IE46761B1 true IE46761B1 (en) 1983-09-21

Family

ID=25059291

Family Applications (1)

Application Number Title Priority Date Filing Date
IE111/78A IE46761B1 (en) 1977-01-19 1978-01-18 Benzazepines

Country Status (15)

Country Link
JP (1) JPS6040423B2 (de)
AU (1) AU510459B2 (de)
BE (1) BE862878A (de)
CA (1) CA1090334A (de)
CH (2) CH642634A5 (de)
DE (1) DE2802086A1 (de)
DK (1) DK19978A (de)
FR (2) FR2378017A1 (de)
GB (2) GB1597912A (de)
HU (1) HU175836B (de)
IE (1) IE46761B1 (de)
LU (1) LU78873A1 (de)
NL (1) NL7800637A (de)
SE (1) SE437265B (de)
ZA (1) ZA777444B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5481290A (en) * 1977-11-17 1979-06-28 Smithkline Corp Benzazepin compound
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4251525A (en) * 1979-05-25 1981-02-17 Smithkline Corporation 3-Allyl-7,8-dihydroxy-6-halo-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives
EP0022330B1 (de) * 1979-07-10 1983-12-21 Smithkline Beckman Corporation Synergistische blutdrucksenkende Zusammensetzungen
WO2005035504A2 (en) * 2003-05-22 2005-04-21 Schering Corporation 5-h -benzo [d] naphth [2, 1-b] azepine derivative as selective d1/d5 receptor antagonists for the treatment of obesity and cns disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH555831A (de) * 1967-02-17 1974-11-15 Scherico Ltd Verfahren zur herstellung von neuen benzazepinen.
US3609139A (en) * 1969-04-01 1971-09-28 Sandoz Ag Substituted dibenzdiazonines
US4011319A (en) * 1975-07-02 1977-03-08 Smithkline Corporation Pharmaceutical compositions and methods involving benzazepine derivatives
GB1561305A (en) * 1975-07-02 1980-02-20 Smithkline Corp Benzazepine derivatives and pharmeceutical compositions containing them

Also Published As

Publication number Publication date
FR2378017A1 (fr) 1978-08-18
AU3246578A (en) 1979-07-26
BE862878A (fr) 1978-07-13
FR2384759B1 (de) 1980-07-18
CH642634A5 (en) 1984-04-30
IE780111L (en) 1978-07-19
LU78873A1 (fr) 1978-06-09
CA1090334A (en) 1980-11-25
NL7800637A (nl) 1978-07-21
JPS5390281A (en) 1978-08-08
GB1597912A (en) 1981-09-16
AU510459B2 (en) 1980-06-26
CH640228A5 (en) 1983-12-30
ZA777444B (en) 1978-10-25
FR2378017B1 (de) 1981-07-10
GB1597911A (en) 1981-09-16
HU175836B (hu) 1980-10-28
FR2384759A1 (fr) 1978-10-20
SE437265B (sv) 1985-02-18
JPS6040423B2 (ja) 1985-09-11
SE7800455L (sv) 1978-07-20
DK19978A (da) 1978-07-20
DE2802086A1 (de) 1978-07-20

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