IE46262B1 - Morphanthridines - Google Patents

Morphanthridines

Info

Publication number
IE46262B1
IE46262B1 IE2279/77A IE227977A IE46262B1 IE 46262 B1 IE46262 B1 IE 46262B1 IE 2279/77 A IE2279/77 A IE 2279/77A IE 227977 A IE227977 A IE 227977A IE 46262 B1 IE46262 B1 IE 46262B1
Authority
IE
Ireland
Prior art keywords
compound
formula
compounds
free base
addition salt
Prior art date
Application number
IE2279/77A
Other languages
English (en)
Other versions
IE46262L (en
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Priority to IE654/82A priority Critical patent/IE46263B1/en
Publication of IE46262L publication Critical patent/IE46262L/xx
Publication of IE46262B1 publication Critical patent/IE46262B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
IE2279/77A 1976-11-10 1977-11-08 Morphanthridines IE46262B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IE654/82A IE46263B1 (en) 1976-11-10 1977-11-08 A morphanthridine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1415776A CH624682A5 (cg-RX-API-DMAC7.html) 1976-11-10 1976-11-10

Publications (2)

Publication Number Publication Date
IE46262L IE46262L (en) 1978-05-10
IE46262B1 true IE46262B1 (en) 1983-04-20

Family

ID=4398460

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2279/77A IE46262B1 (en) 1976-11-10 1977-11-08 Morphanthridines

Country Status (26)

Country Link
US (1) US4308207A (cg-RX-API-DMAC7.html)
JP (1) JPS5929076B2 (cg-RX-API-DMAC7.html)
AT (1) AT366682B (cg-RX-API-DMAC7.html)
AU (1) AU517829B2 (cg-RX-API-DMAC7.html)
BE (1) BE860613A (cg-RX-API-DMAC7.html)
CA (1) CA1086315A (cg-RX-API-DMAC7.html)
CH (1) CH624682A5 (cg-RX-API-DMAC7.html)
CY (1) CY1269A (cg-RX-API-DMAC7.html)
DE (1) DE2748920C2 (cg-RX-API-DMAC7.html)
DK (1) DK140724B (cg-RX-API-DMAC7.html)
ES (1) ES463971A1 (cg-RX-API-DMAC7.html)
FI (1) FI64143C (cg-RX-API-DMAC7.html)
FR (1) FR2370745A1 (cg-RX-API-DMAC7.html)
GB (2) GB1592330A (cg-RX-API-DMAC7.html)
HK (1) HK32282A (cg-RX-API-DMAC7.html)
IE (1) IE46262B1 (cg-RX-API-DMAC7.html)
IL (1) IL53332A (cg-RX-API-DMAC7.html)
KE (1) KE3472A (cg-RX-API-DMAC7.html)
MY (1) MY8400056A (cg-RX-API-DMAC7.html)
NL (1) NL175297C (cg-RX-API-DMAC7.html)
NZ (2) NZ191043A (cg-RX-API-DMAC7.html)
PH (1) PH13515A (cg-RX-API-DMAC7.html)
PT (1) PT67247B (cg-RX-API-DMAC7.html)
SE (1) SE435510B (cg-RX-API-DMAC7.html)
SG (1) SG66584G (cg-RX-API-DMAC7.html)
SU (1) SU686616A3 (cg-RX-API-DMAC7.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3402060A1 (de) * 1984-01-21 1985-08-01 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte 5,11-dihydro-6h-dibenz(b,e)azepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
US5416087A (en) * 1990-10-10 1995-05-16 Wong; Jesse K. Bis-benzo, cyclohepta piperidylidene, piperidine and piperazine compounds, compositions and methods of use
IT1258790B (it) * 1992-01-17 1996-02-29 Angelini Francesco Ist Ricerca Alchil derivati del trazodone
DE69329887T2 (de) * 1992-05-29 2001-05-23 Eli Lilly And Co., Ltd. Thienobenzodiazepinderivate zur Behandlung von Störungen des Zentralnervensystems
KR20050048633A (ko) * 2002-09-18 2005-05-24 에프엠씨 코포레이션 살충성 트라이사이클릭 유도체
WO2004064753A2 (en) * 2003-01-23 2004-08-05 Acadia Pharmaceuticals Inc Use of n-desmethylclozapine to treat human neuropsychiatric disease
US20050085463A1 (en) * 2003-01-23 2005-04-21 Weiner David M. Use of N-desmethylclozapine to treat human neuropsychiatric disease
US20050250767A1 (en) * 2003-01-23 2005-11-10 Weiner David M Use of N-desmethylclozapine to treat human neuropsychiatric disease
BRPI0417749A (pt) * 2003-12-22 2007-04-10 Acadia Pharm Inc composto, método de sintese de composto, bibliotecas combinatórias, composições farmacêuticas e métodos de tratamento de disfunções neuropsiquiátricas
BRPI0509524A (pt) * 2004-04-01 2007-09-18 Acadia Pharm Inc formas cristalinas de n-desmetilclozapina
WO2007053618A1 (en) * 2005-10-31 2007-05-10 Acadia Pharmaceuticals Inc. Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL140242B (nl) * 1963-03-01 1973-11-15 Wander Ag Dr A Werkwijze voor het bereiden van op de 11-plaats door een basische groep gesubstitueerde dibenz (b.f.)(1.4) oxazepinen.
US3389139A (en) * 1963-06-14 1968-06-18 Wander Ag Dr A 6-homopiperazino and piperazinomorphanthridines
GB1006156A (en) * 1963-06-14 1965-09-29 Wander Ag Dr A 6-basic substituted morphanthridines
US3539573A (en) * 1967-03-22 1970-11-10 Jean Schmutz 11-basic substituted dibenzodiazepines and dibenzothiazepines
US3962248A (en) * 1972-04-04 1976-06-08 Sandoz, Inc. Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines
CH601287A5 (cg-RX-API-DMAC7.html) * 1975-08-06 1978-07-14 Sandoz Ag

Also Published As

Publication number Publication date
IL53332A0 (en) 1978-01-31
AU3046777A (en) 1979-05-17
PH13515A (en) 1980-06-03
DK140724B (da) 1979-11-05
SU686616A1 (en) 1979-09-15
JPS5929076B2 (ja) 1984-07-18
SU686616A3 (ru) 1979-09-15
ES463971A1 (es) 1978-12-01
ATA799177A (de) 1981-09-15
NL175297B (nl) 1984-05-16
PT67247B (en) 1979-11-12
IE46262L (en) 1978-05-10
FI64143B (fi) 1983-06-30
FI64143C (fi) 1983-10-10
BE860613A (fr) 1978-05-08
GB1592329A (en) 1981-07-08
GB1592330A (en) 1981-07-08
DE2748920A1 (de) 1978-05-11
JPS5359686A (en) 1978-05-29
CY1269A (en) 1984-11-23
FR2370745A1 (fr) 1978-06-09
DE2748920C2 (de) 1982-12-02
FR2370745B1 (cg-RX-API-DMAC7.html) 1980-08-22
DK140724C (cg-RX-API-DMAC7.html) 1980-03-31
FI773273A7 (fi) 1978-05-11
KE3472A (en) 1984-11-09
CH624682A5 (cg-RX-API-DMAC7.html) 1981-08-14
DK485677A (cg-RX-API-DMAC7.html) 1978-05-11
NZ191043A (en) 1980-09-12
US4308207A (en) 1981-12-29
NL175297C (nl) 1984-10-16
CA1086315A (en) 1980-09-23
MY8400056A (en) 1984-12-31
NZ185642A (en) 1980-09-12
SE435510B (sv) 1984-10-01
IL53332A (en) 1981-11-30
AU517829B2 (en) 1981-08-27
HK32282A (en) 1982-07-23
SE7712387L (sv) 1978-05-11
AT366682B (de) 1982-04-26
PT67247A (en) 1977-12-01
NL7712171A (nl) 1978-05-12
SG66584G (en) 1985-03-15

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