IE44393B1 - New chephalosporins - Google Patents

New chephalosporins

Info

Publication number
IE44393B1
IE44393B1 IE2377/76A IE237776A IE44393B1 IE 44393 B1 IE44393 B1 IE 44393B1 IE 2377/76 A IE2377/76 A IE 2377/76A IE 237776 A IE237776 A IE 237776A IE 44393 B1 IE44393 B1 IE 44393B1
Authority
IE
Ireland
Prior art keywords
cephem
methoxy
carboxylic acid
compound according
tetrazol
Prior art date
Application number
IE2377/76A
Other languages
English (en)
Other versions
IE44393L (en
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/704,142 external-priority patent/US4118491A/en
Application filed by Smithkline Corp filed Critical Smithkline Corp
Priority to IE1645/80A priority Critical patent/IE44395B1/en
Priority to IE1644/80A priority patent/IE44394B1/en
Publication of IE44393L publication Critical patent/IE44393L/xx
Publication of IE44393B1 publication Critical patent/IE44393B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IE2377/76A 1975-10-30 1976-10-27 New chephalosporins IE44393B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IE1645/80A IE44395B1 (en) 1975-10-30 1976-10-27 7-aminocephalosporin intermediates
IE1644/80A IE44394B1 (en) 1975-10-30 1976-10-27 Substituted tetrazole 5-thiols

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62716475A 1975-10-30 1975-10-30
US66583776A 1976-03-11 1976-03-11
US05/704,142 US4118491A (en) 1976-03-11 1976-07-12 7-Acyl-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them

Publications (2)

Publication Number Publication Date
IE44393L IE44393L (en) 1977-09-11
IE44393B1 true IE44393B1 (en) 1981-11-18

Family

ID=27417417

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2377/76A IE44393B1 (en) 1975-10-30 1976-10-27 New chephalosporins

Country Status (17)

Country Link
JP (1) JPS6053026B2 (enrdf_load_html_response)
AT (1) AT353957B (enrdf_load_html_response)
AU (1) AU505141B2 (enrdf_load_html_response)
CA (1) CA1071188A (enrdf_load_html_response)
CH (1) CH627757A5 (enrdf_load_html_response)
DE (1) DE2649545A1 (enrdf_load_html_response)
DK (1) DK463176A (enrdf_load_html_response)
ES (1) ES452769A1 (enrdf_load_html_response)
FI (1) FI60868C (enrdf_load_html_response)
FR (3) FR2361896A1 (enrdf_load_html_response)
GB (3) GB1570093A (enrdf_load_html_response)
GR (1) GR61667B (enrdf_load_html_response)
IE (1) IE44393B1 (enrdf_load_html_response)
IL (3) IL50546A (enrdf_load_html_response)
LU (1) LU76092A1 (enrdf_load_html_response)
NL (1) NL7612010A (enrdf_load_html_response)
SE (3) SE435291B (enrdf_load_html_response)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117123A (en) * 1977-06-09 1978-09-26 Smithkline Corporation 7-Acylamino-3-[1-(2-sulfamidoethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids
AT383811B (de) * 1983-09-22 1987-08-25 Biochemie Gmbh Verfahren zur herstellung von monoalkalisalzen von 7-amino-3-cephem-4-carbonsaeurederivaten
US4717531A (en) * 1983-09-23 1988-01-05 Westinghouse Electric Corp. Fuel transfer system upender using translation drive

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR207752A1 (es) * 1973-03-30 1976-10-29 Fujisawa Pharmaceutical Co Procedimiento para obtener acidos 7-amino-sustituido-3-tiometilsustituido-3-cefem-4-carboxilicos
NL7414119A (nl) * 1973-10-31 1975-05-02 Fujisawa Pharmaceutical Co Werkwijze ter bereiding van 1h-tetrazool-5-thiol- derivaten en 1-gesubstitueerde 1h-tetrazool- -5-thiolen.
GB1449420A (en) * 1973-11-26 1976-09-15 Sankyo Co 7alpha-methoxycephalosporing derivatives
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid

Also Published As

Publication number Publication date
FI60868B (fi) 1981-12-31
CA1071188A (en) 1980-02-05
SE8006413L (sv) 1980-09-12
FR2361896A1 (fr) 1978-03-17
AU505141B2 (en) 1979-11-08
IE44393L (en) 1977-09-11
SE437025B (sv) 1985-02-04
IL56758A0 (en) 1979-05-31
AU1870276A (en) 1978-04-20
ATA807276A (de) 1979-05-15
GR61667B (en) 1978-12-05
ES452769A1 (es) 1978-01-16
JPS5257191A (en) 1977-05-11
FR2351982B1 (enrdf_load_html_response) 1981-07-03
NL7612010A (nl) 1977-05-03
GB1570094A (en) 1980-06-25
IL56757A0 (en) 1979-05-31
FR2337720B1 (enrdf_load_html_response) 1981-07-10
FR2337720A1 (fr) 1977-08-05
AT353957B (de) 1979-12-10
FI60868C (fi) 1982-04-13
SE435291B (sv) 1984-09-17
DE2649545A1 (de) 1977-05-12
IL50546A (en) 1980-07-31
GB1570093A (en) 1980-06-25
JPS6053026B2 (ja) 1985-11-22
DK463176A (da) 1977-05-01
FI763044A7 (enrdf_load_html_response) 1977-05-01
SE452621B (sv) 1987-12-07
FR2361896B1 (enrdf_load_html_response) 1979-02-23
GB1570095A (en) 1980-06-25
SE7610722L (sv) 1977-05-01
LU76092A1 (enrdf_load_html_response) 1977-05-17
SE8006414L (sv) 1980-09-12
CH627757A5 (en) 1982-01-29
FR2351982A1 (fr) 1977-12-16
IL50546A0 (en) 1976-11-30

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