IL56758A0 - Substitued cephalosporins and their preparation - Google Patents

Substitued cephalosporins and their preparation

Info

Publication number
IL56758A0
IL56758A0 IL56758A IL5675879A IL56758A0 IL 56758 A0 IL56758 A0 IL 56758A0 IL 56758 A IL56758 A IL 56758A IL 5675879 A IL5675879 A IL 5675879A IL 56758 A0 IL56758 A0 IL 56758A0
Authority
IL
Israel
Prior art keywords
substitued
cephalosporins
preparation
substitued cephalosporins
Prior art date
Application number
IL56758A
Other languages
English (en)
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/704,142 external-priority patent/US4118491A/en
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of IL56758A0 publication Critical patent/IL56758A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL56758A 1975-10-30 1979-02-28 Substitued cephalosporins and their preparation IL56758A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62716475A 1975-10-30 1975-10-30
US66583776A 1976-03-11 1976-03-11
US05/704,142 US4118491A (en) 1976-03-11 1976-07-12 7-Acyl-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them

Publications (1)

Publication Number Publication Date
IL56758A0 true IL56758A0 (en) 1979-05-31

Family

ID=27417417

Family Applications (3)

Application Number Title Priority Date Filing Date
IL50546A IL50546A (en) 1975-10-30 1976-09-23 7-acyl-3-(1-(2-sulfaminoethyl)tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid derivatives and pharmaceutical compositions containing them
IL56757A IL56757A0 (en) 1975-10-30 1979-02-28 Tetrazole thiol and preparation
IL56758A IL56758A0 (en) 1975-10-30 1979-02-28 Substitued cephalosporins and their preparation

Family Applications Before (2)

Application Number Title Priority Date Filing Date
IL50546A IL50546A (en) 1975-10-30 1976-09-23 7-acyl-3-(1-(2-sulfaminoethyl)tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid derivatives and pharmaceutical compositions containing them
IL56757A IL56757A0 (en) 1975-10-30 1979-02-28 Tetrazole thiol and preparation

Country Status (17)

Country Link
JP (1) JPS6053026B2 (xx)
AT (1) AT353957B (xx)
AU (1) AU505141B2 (xx)
CA (1) CA1071188A (xx)
CH (1) CH627757A5 (xx)
DE (1) DE2649545A1 (xx)
DK (1) DK463176A (xx)
ES (1) ES452769A1 (xx)
FI (1) FI60868C (xx)
FR (3) FR2361896A1 (xx)
GB (3) GB1570094A (xx)
GR (1) GR61667B (xx)
IE (1) IE44393B1 (xx)
IL (3) IL50546A (xx)
LU (1) LU76092A1 (xx)
NL (1) NL7612010A (xx)
SE (3) SE452621B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117123A (en) * 1977-06-09 1978-09-26 Smithkline Corporation 7-Acylamino-3-[1-(2-sulfamidoethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids
AT383811B (de) * 1983-09-22 1987-08-25 Biochemie Gmbh Verfahren zur herstellung von monoalkalisalzen von 7-amino-3-cephem-4-carbonsaeurederivaten
US4717531A (en) * 1983-09-23 1988-01-05 Westinghouse Electric Corp. Fuel transfer system upender using translation drive

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR207752A1 (es) * 1973-03-30 1976-10-29 Fujisawa Pharmaceutical Co Procedimiento para obtener acidos 7-amino-sustituido-3-tiometilsustituido-3-cefem-4-carboxilicos
US4110338A (en) * 1973-10-31 1978-08-29 Fujisawa Pharmaceutical Co., Ltd. Product and preparation of 1H-tetrazole-5-thiol derivatives
GB1449420A (en) * 1973-11-26 1976-09-15 Sankyo Co 7alpha-methoxycephalosporing derivatives
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid

Also Published As

Publication number Publication date
FR2351982B1 (xx) 1981-07-03
FR2337720B1 (xx) 1981-07-10
ES452769A1 (es) 1978-01-16
IE44393L (en) 1977-09-11
JPS5257191A (en) 1977-05-11
IL56757A0 (en) 1979-05-31
GR61667B (en) 1978-12-05
FR2361896B1 (xx) 1979-02-23
FI60868B (fi) 1981-12-31
GB1570095A (en) 1980-06-25
IL50546A0 (en) 1976-11-30
IL50546A (en) 1980-07-31
SE7610722L (sv) 1977-05-01
LU76092A1 (xx) 1977-05-17
CA1071188A (en) 1980-02-05
FR2337720A1 (fr) 1977-08-05
CH627757A5 (en) 1982-01-29
AT353957B (de) 1979-12-10
AU505141B2 (en) 1979-11-08
ATA807276A (de) 1979-05-15
AU1870276A (en) 1978-04-20
GB1570093A (en) 1980-06-25
DK463176A (da) 1977-05-01
SE435291B (sv) 1984-09-17
JPS6053026B2 (ja) 1985-11-22
FI763044A (xx) 1977-05-01
SE452621B (sv) 1987-12-07
SE437025B (sv) 1985-02-04
SE8006414L (sv) 1980-09-12
GB1570094A (en) 1980-06-25
NL7612010A (nl) 1977-05-03
SE8006413L (sv) 1980-09-12
DE2649545A1 (de) 1977-05-12
FR2351982A1 (fr) 1977-12-16
FI60868C (fi) 1982-04-13
IE44393B1 (en) 1981-11-18
FR2361896A1 (fr) 1978-03-17

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