IE39506B1 - Process for preparing cephalosporins - Google Patents

Process for preparing cephalosporins

Info

Publication number
IE39506B1
IE39506B1 IE1263/74A IE126374A IE39506B1 IE 39506 B1 IE39506 B1 IE 39506B1 IE 1263/74 A IE1263/74 A IE 1263/74A IE 126374 A IE126374 A IE 126374A IE 39506 B1 IE39506 B1 IE 39506B1
Authority
IE
Ireland
Prior art keywords
aminoacetamido
july
carboxylic acid
compound
cephalosporins
Prior art date
Application number
IE1263/74A
Other versions
IE39506L (en
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of IE39506L publication Critical patent/IE39506L/en
Publication of IE39506B1 publication Critical patent/IE39506B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D501/06—Acylation of 7-aminocephalosporanic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

1473090 Cephalosporins LILLY INDUSTRIES Ltd 18 July 1974 [19 July 1973] 34337/73 Heading C2C A 7 - α - aminoacetamido - cephalosporin - 4- carboxylic acid is made by reacting a 7-aminocephalosporin-4-carboxylic acid ester with a reactive derivative of an α-aminoacetic acid, in which the amino group is protected by forming an enamine with a #-dicarbonyl compound; removing the amino protecting group from the product; adding sufficient hydrazine or its derivative (e.g. semicarbazide) to prevent reaction of the liberated dicarbonyl compound; and, if desired de-esterifying the resulting 7-α- aminoacetamido compound. [GB1473090A]
IE1263/74A 1973-07-19 1974-06-17 Process for preparing cephalosporins IE39506B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3433773A GB1473090A (en) 1973-07-19 1973-07-19

Publications (2)

Publication Number Publication Date
IE39506L IE39506L (en) 1975-01-19
IE39506B1 true IE39506B1 (en) 1978-10-25

Family

ID=10364389

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1263/74A IE39506B1 (en) 1973-07-19 1974-06-17 Process for preparing cephalosporins

Country Status (25)

Country Link
JP (1) JPS6113478B2 (en)
AR (1) AR211686A1 (en)
AT (1) AT338972B (en)
BE (1) BE817790A (en)
BG (1) BG25799A3 (en)
CA (1) CA1024508A (en)
CH (1) CH582189A5 (en)
CS (1) CS188188B2 (en)
DD (1) DD112134A5 (en)
DE (1) DE2434017C3 (en)
DK (1) DK142144B (en)
ES (1) ES428386A1 (en)
FR (1) FR2237635B1 (en)
GB (1) GB1473090A (en)
HU (1) HU168065B (en)
IE (1) IE39506B1 (en)
IL (1) IL45101A (en)
NL (1) NL187811C (en)
PH (1) PH11147A (en)
PL (1) PL91364B1 (en)
RO (1) RO64483A (en)
SE (1) SE415765B (en)
SU (1) SU622409A3 (en)
YU (1) YU182574A (en)
ZA (1) ZA743890B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1126544B (en) * 1979-12-07 1986-05-21 Dobfar Spa PROCEDURE FOR THE PREPARATION OF 7-AMINO-DESACETOXY CEPHALOSPORANIC ACID DERIVATIVES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1602620A (en) * 1965-03-08 1971-01-04 Antibacterial cephalosporin cpds

Also Published As

Publication number Publication date
BG25799A3 (en) 1978-12-12
NL7409299A (en) 1975-01-21
BE817790A (en) 1975-01-20
JPS6113478B2 (en) 1986-04-14
FR2237635B1 (en) 1978-07-21
AT338972B (en) 1977-09-26
DD112134A5 (en) 1975-03-20
IL45101A (en) 1977-01-31
AU7056574A (en) 1976-01-08
CS188188B2 (en) 1979-02-28
DK142144B (en) 1980-09-08
GB1473090A (en) 1977-05-11
YU182574A (en) 1982-05-31
DE2434017C3 (en) 1980-04-17
SE415765B (en) 1980-10-27
PH11147A (en) 1977-10-27
RO64483A (en) 1979-08-15
DE2434017B2 (en) 1979-08-02
FR2237635A1 (en) 1975-02-14
DE2434017A1 (en) 1975-02-06
SU622409A3 (en) 1978-08-30
CH582189A5 (en) 1976-11-30
ES428386A1 (en) 1976-07-16
ATA597874A (en) 1977-01-15
SE7409415L (en) 1975-01-20
DK383974A (en) 1975-03-17
DK142144C (en) 1981-02-09
CA1024508A (en) 1978-01-17
AR211686A1 (en) 1978-02-28
ZA743890B (en) 1976-01-28
NL187811B (en) 1991-08-16
IE39506L (en) 1975-01-19
JPS5040588A (en) 1975-04-14
IL45101A0 (en) 1974-09-10
NL187811C (en) 1992-01-16
PL91364B1 (en) 1977-02-28
HU168065B (en) 1976-02-28

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