GB1473090A - - Google Patents

Info

Publication number
GB1473090A
GB1473090A GB3433773A GB3433773A GB1473090A GB 1473090 A GB1473090 A GB 1473090A GB 3433773 A GB3433773 A GB 3433773A GB 3433773 A GB3433773 A GB 3433773A GB 1473090 A GB1473090 A GB 1473090A
Authority
GB
United Kingdom
Prior art keywords
aminoacetamido
july
carboxylic acid
compound
dicarbonyl compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3433773A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to GB3433773A priority Critical patent/GB1473090A/en
Priority to IE1263/74A priority patent/IE39506B1/en
Priority to CA202,732A priority patent/CA1024508A/en
Priority to ZA00743890A priority patent/ZA743890B/en
Priority to IL45101A priority patent/IL45101A/en
Priority to AU70565/74A priority patent/AU485793B2/en
Priority to YU01825/74A priority patent/YU182574A/en
Priority to PH16018A priority patent/PH11147A/en
Priority to CH948774A priority patent/CH582189A5/xx
Priority to NLAANVRAGE7409299,A priority patent/NL187811C/en
Priority to CS744896A priority patent/CS188188B2/en
Priority to JP49079044A priority patent/JPS6113478B2/ja
Priority to DE2434017A priority patent/DE2434017C3/en
Priority to FR7424795A priority patent/FR2237635B1/fr
Priority to DK383974AA priority patent/DK142144B/en
Priority to ES428386A priority patent/ES428386A1/en
Priority to DD179967A priority patent/DD112134A5/xx
Priority to SE7409415A priority patent/SE415765B/en
Priority to SU742045556A priority patent/SU622409A3/en
Priority to PL1974172840A priority patent/PL91364B1/pl
Priority to AR254755A priority patent/AR211686A1/en
Priority to BE146673A priority patent/BE817790A/en
Priority to HULI261A priority patent/HU168065B/hu
Priority to BG027304A priority patent/BG25799A3/en
Priority to AT597874A priority patent/AT338972B/en
Priority to RO7479536A priority patent/RO64483A/en
Publication of GB1473090A publication Critical patent/GB1473090A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D501/06Acylation of 7-aminocephalosporanic acid
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

1473090 Cephalosporins LILLY INDUSTRIES Ltd 18 July 1974 [19 July 1973] 34337/73 Heading C2C A 7 - α - aminoacetamido - cephalosporin - 4- carboxylic acid is made by reacting a 7-aminocephalosporin-4-carboxylic acid ester with a reactive derivative of an α-aminoacetic acid, in which the amino group is protected by forming an enamine with a #-dicarbonyl compound; removing the amino protecting group from the product; adding sufficient hydrazine or its derivative (e.g. semicarbazide) to prevent reaction of the liberated dicarbonyl compound; and, if desired de-esterifying the resulting 7-α- aminoacetamido compound.
GB3433773A 1973-07-19 1973-07-19 Expired GB1473090A (en)

Priority Applications (26)

Application Number Priority Date Filing Date Title
GB3433773A GB1473090A (en) 1973-07-19 1973-07-19
IE1263/74A IE39506B1 (en) 1973-07-19 1974-06-17 Process for preparing cephalosporins
CA202,732A CA1024508A (en) 1973-07-19 1974-06-18 Process for preparing cephalosporins
ZA00743890A ZA743890B (en) 1973-07-19 1974-06-18 Process for preparing cephalosporins
IL45101A IL45101A (en) 1973-07-19 1974-06-21 Process for preparing cephalosporins
AU70565/74A AU485793B2 (en) 1973-07-19 1974-06-27 Process for preparing cephalosporins
YU01825/74A YU182574A (en) 1973-07-19 1974-06-28 Process for the synthesis of cephalosporin
PH16018A PH11147A (en) 1973-07-19 1974-07-05 Process for preparing 7-o(-acetamido cephalosporing-4-carboxylic acid
CH948774A CH582189A5 (en) 1973-07-19 1974-07-10
NLAANVRAGE7409299,A NL187811C (en) 1973-07-19 1974-07-10 PROCESS FOR PREPARING A 7- (ALFA-AMINOACETAMIDO) -3-CEFEM-4-CARBONIC ACID, AND METHOD FOR PREPARING A MEDICINAL PRODUCT WITH ANTIBACTERIAL ACTION
CS744896A CS188188B2 (en) 1973-07-19 1974-07-10 Method of producing 7-alpha-amino acetamido cephalosporanic acid
JP49079044A JPS6113478B2 (en) 1973-07-19 1974-07-10
DE2434017A DE2434017C3 (en) 1973-07-19 1974-07-16 Process for the preparation of 7-α-aminoacetamidocephalosporin-4-carboxylic acids
FR7424795A FR2237635B1 (en) 1973-07-19 1974-07-17
DK383974AA DK142144B (en) 1973-07-19 1974-07-17 Process for the preparation of 7-alpha-aminoacetamido-cephalosporin-4-carboxylic acid derivatives.
ES428386A ES428386A1 (en) 1973-07-19 1974-07-17 A procedure for preparing 7-alpha-aminoacetamide acid cefalosporin-4-carboxylic. (Machine-translation by Google Translate, not legally binding)
DD179967A DD112134A5 (en) 1973-07-19 1974-07-17
SE7409415A SE415765B (en) 1973-07-19 1974-07-18 PROCEDURE FOR PREPARING A 7-ALFA-AMINOACETAMIDOCEPHALOSPORIN-4-CARBONIC ACID
SU742045556A SU622409A3 (en) 1973-07-19 1974-07-18 Method of producing 7-alpha-aminoacetamidocephalosiphanic acid
PL1974172840A PL91364B1 (en) 1973-07-19 1974-07-18
AR254755A AR211686A1 (en) 1973-07-19 1974-07-18 PROCEDURE FOR PREPARING A 7-A-AMINOACETAMIDOCEPHALOSPORIN-4-CARBOXYL ACID
BE146673A BE817790A (en) 1973-07-19 1974-07-18 PROCESS FOR THE PREPARATION OF CEPHALOSPORIN DERIVATIVES AND PRODUCTS OBTAINED
HULI261A HU168065B (en) 1973-07-19 1974-07-18
BG027304A BG25799A3 (en) 1973-07-19 1974-07-19 A method of obtaining 7-alpha-amineacetamidecephalosporine-4-carbonic acid
AT597874A AT338972B (en) 1973-07-19 1974-07-19 PROCESS FOR THE PREPARATION OF 7-ALFA-AMINOACETAMIDOCEPHALOSPORIN-4-CARBONIC ACIDS
RO7479536A RO64483A (en) 1973-07-19 1974-07-19 PROCESS FOR THE PREPARATION OF CEPHALEXIN AND CEPHRADINE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3433773A GB1473090A (en) 1973-07-19 1973-07-19

Publications (1)

Publication Number Publication Date
GB1473090A true GB1473090A (en) 1977-05-11

Family

ID=10364389

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3433773A Expired GB1473090A (en) 1973-07-19 1973-07-19

Country Status (25)

Country Link
JP (1) JPS6113478B2 (en)
AR (1) AR211686A1 (en)
AT (1) AT338972B (en)
BE (1) BE817790A (en)
BG (1) BG25799A3 (en)
CA (1) CA1024508A (en)
CH (1) CH582189A5 (en)
CS (1) CS188188B2 (en)
DD (1) DD112134A5 (en)
DE (1) DE2434017C3 (en)
DK (1) DK142144B (en)
ES (1) ES428386A1 (en)
FR (1) FR2237635B1 (en)
GB (1) GB1473090A (en)
HU (1) HU168065B (en)
IE (1) IE39506B1 (en)
IL (1) IL45101A (en)
NL (1) NL187811C (en)
PH (1) PH11147A (en)
PL (1) PL91364B1 (en)
RO (1) RO64483A (en)
SE (1) SE415765B (en)
SU (1) SU622409A3 (en)
YU (1) YU182574A (en)
ZA (1) ZA743890B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1126544B (en) * 1979-12-07 1986-05-21 Dobfar Spa PROCEDURE FOR THE PREPARATION OF 7-AMINO-DESACETOXY CEPHALOSPORANIC ACID DERIVATIVES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1602620A (en) * 1965-03-08 1971-01-04 Antibacterial cephalosporin cpds

Also Published As

Publication number Publication date
AU7056574A (en) 1976-01-08
IE39506B1 (en) 1978-10-25
NL187811C (en) 1992-01-16
SE7409415L (en) 1975-01-20
IL45101A (en) 1977-01-31
DD112134A5 (en) 1975-03-20
IL45101A0 (en) 1974-09-10
HU168065B (en) 1976-02-28
BE817790A (en) 1975-01-20
DK383974A (en) 1975-03-17
PL91364B1 (en) 1977-02-28
SE415765B (en) 1980-10-27
BG25799A3 (en) 1978-12-12
ATA597874A (en) 1977-01-15
AR211686A1 (en) 1978-02-28
PH11147A (en) 1977-10-27
DE2434017C3 (en) 1980-04-17
CA1024508A (en) 1978-01-17
RO64483A (en) 1979-08-15
CS188188B2 (en) 1979-02-28
JPS5040588A (en) 1975-04-14
NL187811B (en) 1991-08-16
CH582189A5 (en) 1976-11-30
DE2434017A1 (en) 1975-02-06
IE39506L (en) 1975-01-19
FR2237635B1 (en) 1978-07-21
SU622409A3 (en) 1978-08-30
FR2237635A1 (en) 1975-02-14
DE2434017B2 (en) 1979-08-02
DK142144C (en) 1981-02-09
NL7409299A (en) 1975-01-21
DK142144B (en) 1980-09-08
YU182574A (en) 1982-05-31
JPS6113478B2 (en) 1986-04-14
AT338972B (en) 1977-09-26
ZA743890B (en) 1976-01-28
ES428386A1 (en) 1976-07-16

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years

Effective date: 19940717