FR1602620A - Antibacterial cephalosporin cpds - Google Patents

Antibacterial cephalosporin cpds

Info

Publication number
FR1602620A
FR1602620A FR1602620DA FR1602620A FR 1602620 A FR1602620 A FR 1602620A FR 1602620D A FR1602620D A FR 1602620DA FR 1602620 A FR1602620 A FR 1602620A
Authority
FR
France
Prior art keywords
formula
lower alkyl
cpds
pyridino
aco
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Other languages
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Application granted granted Critical
Publication of FR1602620A publication Critical patent/FR1602620A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/32—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

(A) Cephalosporin cpds. of formula (I):- (I) R1 = AcO, pyridino R2 = OH when R1 = AcO = O- when R1 = pyridino Ac = CH3CO R4 = H, Me, Et m, n = 0 or 1 R3 = 1-4C alkyl, 3-6C cycloalkyl, phenyl, naphthyl, thienyl, furyl, benzofuryl, benzothienyl, indolyl, pyridyl (B) Intermediates of formula (II):- R5 = H, lower alkyl, Ph R6 = H, lower alkyl, aralkyl, Ph R7 = H, lower alkyl/alkoxy, Ph or R6+R7 complete a benzene/naphthalene ring or R5+R7 complete a 5-7C cycloaliphatic ring. (C) Intermediates of formula (III) or a resonance hybrid of this and other possible forms:- (I) are active against both gram +ve and gram-ve bacteria.
FR1602620D 1965-03-08 1966-01-18 Antibacterial cephalosporin cpds Expired FR1602620A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43804565A 1965-03-08 1965-03-08

Publications (1)

Publication Number Publication Date
FR1602620A true FR1602620A (en) 1971-01-04

Family

ID=23738984

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1602620D Expired FR1602620A (en) 1965-03-08 1966-01-18 Antibacterial cephalosporin cpds

Country Status (1)

Country Link
FR (1) FR1602620A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2237635A1 (en) * 1973-07-19 1975-02-14 Lilly Industries Ltd

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2237635A1 (en) * 1973-07-19 1975-02-14 Lilly Industries Ltd

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Legal Events

Date Code Title Description
ST Notification of lapse
RC Opposition against decision of lapse
DA Annulment of decision of lapse