IE36734B1 - A process for the manufacture of benzodiazepine derivatives - Google Patents
A process for the manufacture of benzodiazepine derivativesInfo
- Publication number
- IE36734B1 IE36734B1 IE926/72A IE92672A IE36734B1 IE 36734 B1 IE36734 B1 IE 36734B1 IE 926/72 A IE926/72 A IE 926/72A IE 92672 A IE92672 A IE 92672A IE 36734 B1 IE36734 B1 IE 36734B1
- Authority
- IE
- Ireland
- Prior art keywords
- manufacture
- benzodiazepine derivatives
- mole
- halobenzoyl
- convulsants
- Prior art date
Links
- 229940053197 benzodiazepine derivative antiepileptics Drugs 0.000 title 1
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- VKYKSIONXSXAKP-UHFFFAOYSA-N hexamethylenetetramine Chemical compound C1N(C2)CN3CN1CN2C3 VKYKSIONXSXAKP-UHFFFAOYSA-N 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 235000010299 hexamethylene tetramine Nutrition 0.000 abstract 1
- 239000004312 hexamethylene tetramine Substances 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3210771A GB1383647A (en) | 1971-07-08 | 1971-07-08 | Process for the manufacture of benzodiazepine derivatives |
| US18750071A | 1971-10-07 | 1971-10-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE36734L IE36734L (en) | 1973-01-08 |
| IE36734B1 true IE36734B1 (en) | 1977-02-16 |
Family
ID=26261215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE926/72A IE36734B1 (en) | 1971-07-08 | 1972-07-03 | A process for the manufacture of benzodiazepine derivatives |
Country Status (17)
-
0
- BE BE785963D patent/BE785963A/xx not_active IP Right Cessation
-
1972
- 1972-06-09 CH CH859572A patent/CH569007A5/xx not_active IP Right Cessation
- 1972-07-03 IE IE926/72A patent/IE36734B1/xx unknown
- 1972-07-06 YU YU01770/72A patent/YU177072A/xx unknown
- 1972-07-06 IL IL39844A patent/IL39844A/xx unknown
- 1972-07-06 FR FR7224437A patent/FR2144830A1/fr active Granted
- 1972-07-07 FI FI1932/72A patent/FI57258C/fi active
- 1972-07-07 JP JP6811472A patent/JPS5331878B1/ja active Pending
- 1972-07-07 NO NO2454/72A patent/NO132320C/no unknown
- 1972-07-07 DK DK341372A patent/DK147482C/da active
- 1972-07-07 HU HUHO1496A patent/HU166414B/hu unknown
- 1972-07-07 AT AT584472A patent/AT327198B/de not_active IP Right Cessation
- 1972-07-07 SE SE7209051A patent/SE416651B/xx unknown
- 1972-07-07 AU AU44361/72A patent/AU458347B2/en not_active Expired
- 1972-07-07 NL NL7209490.A patent/NL164282C/xx not_active IP Right Cessation
- 1972-07-07 SE SE7209050A patent/SE416807B/xx unknown
- 1972-07-07 ES ES404626A patent/ES404626A1/es not_active Expired
- 1972-07-07 AR AR242957A patent/AR192656A1/es active
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