FR2054955A5 - Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn - Google Patents

Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn

Info

Publication number
FR2054955A5
FR2054955A5 FR7025573A FR7025573A FR2054955A5 FR 2054955 A5 FR2054955 A5 FR 2054955A5 FR 7025573 A FR7025573 A FR 7025573A FR 7025573 A FR7025573 A FR 7025573A FR 2054955 A5 FR2054955 A5 FR 2054955A5
Authority
FR
France
Prior art keywords
methylenedioxy
quinolone
antimicrobial
alkyl
subst
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7025573A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to FR7025573A priority Critical patent/FR2054955A5/en
Application granted granted Critical
Publication of FR2054955A5 publication Critical patent/FR2054955A5/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1-Substd. 6,7-methylenedioxy-4-quinolone-3-carboxylic acid derivs. of formula (I): (where R is alkyl or alkenyl and R1 is H or alkyl) are prepd. by condensing a dialkyl N-substd. -3,4-methylenedioxyanilinomethylene malonate of formula (II): (where R1' is the same alkyl as defined for R1) at 0-200 degrees C using an acid anhydride, an acid, or mixtures of these, to obtain cpd. (I) or the 1-substd. 3-alkoxycarbonyl-4-halo-6,7-methylenedioxy quinolinium salt of formula (III): (where X and Y are halogen). Cpd. (III) is reacted at 0-200 degrees C with a cpd. R2-OH (where R2 is H or alkyl) to obtain (I). Cpds. (I) are specif. used in antimicrobial compns.
FR7025573A 1970-07-09 1970-07-09 Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn Expired FR2054955A5 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7025573A FR2054955A5 (en) 1970-07-09 1970-07-09 Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7025573A FR2054955A5 (en) 1970-07-09 1970-07-09 Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn

Publications (1)

Publication Number Publication Date
FR2054955A5 true FR2054955A5 (en) 1971-05-07

Family

ID=9058539

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7025573A Expired FR2054955A5 (en) 1970-07-09 1970-07-09 Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn

Country Status (1)

Country Link
FR (1) FR2054955A5 (en)

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Legal Events

Date Code Title Description
ST Notification of lapse