BE753153A - Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn - Google Patents

Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn

Info

Publication number
BE753153A
BE753153A BE753153DA BE753153A BE 753153 A BE753153 A BE 753153A BE 753153D A BE753153D A BE 753153DA BE 753153 A BE753153 A BE 753153A
Authority
BE
Belgium
Prior art keywords
methylenedioxy
quinolone
antimicrobial
alkyl
subst
Prior art date
Application number
Other languages
French (fr)
Inventor
T Nakagome
H Agui
T Mitani
M Nakashita
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of BE753153A publication Critical patent/BE753153A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1-Substd. 6,7-methylenedioxy-4-quinolone-3-carboxylic acid derivs. of formula (I): (where R is alkyl or alkenyl and R1 is H or alkyl) are prepd. by condensing a dialkyl N-substd. -3,4-methylenedioxyanilinomethylene malonate of formula (II): (where R1' is the same alkyl as defined for R1) at 0-200 degrees C using an acid anhydride, an acid, or mixtures of these, to obtain cpd. (I) or the 1-substd. 3-alkoxycarbonyl-4-halo-6,7-methylenedioxy quinolinium salt of formula (III): (where X and Y are halogen). Cpd. (III) is reacted at 0-200 degrees C with a cpd. R2-OH (where R2 is H or alkyl) to obtain (I). Cpds. (I) are specif. used in antimicrobial compns.
BE753153D 1970-07-08 1970-07-08 Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn BE753153A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE753153 1970-07-08

Publications (1)

Publication Number Publication Date
BE753153A true BE753153A (en) 1970-12-16

Family

ID=3856748

Family Applications (1)

Application Number Title Priority Date Filing Date
BE753153D BE753153A (en) 1970-07-08 1970-07-08 Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn

Country Status (1)

Country Link
BE (1) BE753153A (en)

Similar Documents

Publication Publication Date Title
GB1097544A (en) Phenoxy-substituted alkanols
GB1383083A (en) Thiazolidine derivatives
BG27903A3 (en) Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid
FR2205333A1 (en) 6-Phenanthridone-3-carboxylic or-acetic acids - useful as gastric sec-retion inhibitors and anti-ulcer agents
ES439927A1 (en) 7-Methoxy-6-thiatetracyclines and their preparation
GB1171156A (en) Improvements in or relating to Cycloalkane Derivatives and the Manufacture thereof
GB1168455A (en) Preparation and use of Substituted Fluoran Derivatives
GB1295685A (en)
IL36435A (en) Methyl 7-o-methyl-6,8-dideoxy-6-(trans-1-methyl-4-propyl-l-2-pyrrolidinecarboxamido)-1-thio-l-threo-alpha-d-galacto-octopyranoside,the acid addition salts thereof and the production of these
FR2054955A5 (en) Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn
NL7010194A (en) Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn
BE753153A (en) Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn
DK128779B (en) Analogous process for the preparation of 2-arylamino-imidazoline- (2)'s or acid addition salts thereof.
ES376688A1 (en) Benzdiazepine derivatives
ES409637A1 (en) 1,2,3,4,10,10a-hexahydropyrazino{8 1,2:a{9 indole-2-carboxamidines
GB1332697A (en) Benzodiazepine derivatives
ES384795A1 (en) Cyclopropane-carboxylic acid benzothiazylamides
BE816076A (en) N-cyclohexyl-N'-substd-phenyl-benzamides - having anti-inflammatory and analgesic activity with low toxicity
SE7700792L (en) PROCEDURE FOR THE PREPARATION OF N, N'-DICHLOR-ISOPHTHALIC ACID
IE35052L (en) Indenopyridines.
ES335790A1 (en) 2-(2-haloethylamino)-5-halo-benzophenones
ES335892A1 (en) Improvements relating to nitro acridone dyestuffs and their use
FR2222092A1 (en)
GB1090359A (en) New adenosine-ketals
SE395695B (en) PROCEDURE FOR THE PREPARATION OF 4 ', 5-DINITRO-3'-TRIFLUOROMETHYL-2-THIOFENCARBONIC ACID ANILIDE WITH ACTION AGAINST BACTERIA, FUNGIES AND PARASITES