NL7010194A - Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn - Google Patents

Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn

Info

Publication number
NL7010194A
NL7010194A NL7010194A NL7010194A NL7010194A NL 7010194 A NL7010194 A NL 7010194A NL 7010194 A NL7010194 A NL 7010194A NL 7010194 A NL7010194 A NL 7010194A NL 7010194 A NL7010194 A NL 7010194A
Authority
NL
Netherlands
Prior art keywords
methylenedioxy
quinolone
antimicrobial
alkyl
subst
Prior art date
Application number
NL7010194A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to NL7010194A priority Critical patent/NL7010194A/en
Publication of NL7010194A publication Critical patent/NL7010194A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1-Substd. 6,7-methylenedioxy-4-quinolone-3-carboxylic acid derivs. of formula (I): (where R is alkyl or alkenyl and R1 is H or alkyl) are prepd. by condensing a dialkyl N-substd. -3,4-methylenedioxyanilinomethylene malonate of formula (II): (where R1' is the same alkyl as defined for R1) at 0-200 degrees C using an acid anhydride, an acid, or mixtures of these, to obtain cpd. (I) or the 1-substd. 3-alkoxycarbonyl-4-halo-6,7-methylenedioxy quinolinium salt of formula (III): (where X and Y are halogen). Cpd. (III) is reacted at 0-200 degrees C with a cpd. R2-OH (where R2 is H or alkyl) to obtain (I). Cpds. (I) are specif. used in antimicrobial compns.
NL7010194A 1970-07-09 1970-07-09 Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn NL7010194A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NL7010194A NL7010194A (en) 1970-07-09 1970-07-09 Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7010194A NL7010194A (en) 1970-07-09 1970-07-09 Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn

Publications (1)

Publication Number Publication Date
NL7010194A true NL7010194A (en) 1971-01-12

Family

ID=19810541

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7010194A NL7010194A (en) 1970-07-09 1970-07-09 Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn

Country Status (1)

Country Link
NL (1) NL7010194A (en)

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Legal Events

Date Code Title Description
BV The patent application has lapsed