FR2175634A1 - Carboxymethoxybenzofurans derivs - analgesic antiinflammatory hypotensive activity etc - Google Patents

Carboxymethoxybenzofurans derivs - analgesic antiinflammatory hypotensive activity etc

Info

Publication number
FR2175634A1
FR2175634A1 FR7209230A FR7209230A FR2175634A1 FR 2175634 A1 FR2175634 A1 FR 2175634A1 FR 7209230 A FR7209230 A FR 7209230A FR 7209230 A FR7209230 A FR 7209230A FR 2175634 A1 FR2175634 A1 FR 2175634A1
Authority
FR
France
Prior art keywords
carboxymethoxybenzofurans
derivs
activity etc
hypotensive activity
analgesic antiinflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7209230A
Other languages
French (fr)
Other versions
FR2175634B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR7209230A priority Critical patent/FR2175634A1/en
Publication of FR2175634A1 publication Critical patent/FR2175634A1/en
Application granted granted Critical
Publication of FR2175634B1 publication Critical patent/FR2175634B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7

Abstract

5-Cinnamoyl-4,7-dimethoxy carboxy methoxybenzofurans of formula: where Ar is phenyl opt. substd by >=1 OH, alkoxy (1-4C) or halogen. They have analgesic antiinflammatory, vasodilator diuretic, hypotensive antihistaminic and bronchodilator activity. They are prepd. by saponification of 5-acetyl-4,7-dimethoxy-6-ethoxycarbonylmethoxybenzofuran and condensation of the resultant acid with benzaldehyde.
FR7209230A 1972-03-16 1972-03-16 Carboxymethoxybenzofurans derivs - analgesic antiinflammatory hypotensive activity etc Granted FR2175634A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7209230A FR2175634A1 (en) 1972-03-16 1972-03-16 Carboxymethoxybenzofurans derivs - analgesic antiinflammatory hypotensive activity etc

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7209230A FR2175634A1 (en) 1972-03-16 1972-03-16 Carboxymethoxybenzofurans derivs - analgesic antiinflammatory hypotensive activity etc

Publications (2)

Publication Number Publication Date
FR2175634A1 true FR2175634A1 (en) 1973-10-26
FR2175634B1 FR2175634B1 (en) 1975-04-25

Family

ID=9095314

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7209230A Granted FR2175634A1 (en) 1972-03-16 1972-03-16 Carboxymethoxybenzofurans derivs - analgesic antiinflammatory hypotensive activity etc

Country Status (1)

Country Link
FR (1) FR2175634A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001098291A2 (en) * 2000-06-20 2001-12-27 Atherogenics, Inc. 1,3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat vcam-1 mediated disorders
US7078431B2 (en) 2000-06-20 2006-07-18 Atherogenics, Inc. 1,3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat VCAM-1 mediated disorders
US7094801B2 (en) 2001-12-19 2006-08-22 Atherogenics, Inc. Chalcone derivatives and their use to treat diseases

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001098291A2 (en) * 2000-06-20 2001-12-27 Atherogenics, Inc. 1,3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat vcam-1 mediated disorders
WO2001098291A3 (en) * 2000-06-20 2002-05-16 Atherogenics Inc 1,3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat vcam-1 mediated disorders
US6608101B1 (en) 2000-06-20 2003-08-19 Atherogenics, Inc. 1, 3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat VCAM-1 mediated disorders
US7078431B2 (en) 2000-06-20 2006-07-18 Atherogenics, Inc. 1,3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat VCAM-1 mediated disorders
US7094801B2 (en) 2001-12-19 2006-08-22 Atherogenics, Inc. Chalcone derivatives and their use to treat diseases

Also Published As

Publication number Publication date
FR2175634B1 (en) 1975-04-25

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Legal Events

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