SE8302193L - N-(1-substituerade-3-pyrrolidinyl)-bensamider och tiobensamider - Google Patents

N-(1-substituerade-3-pyrrolidinyl)-bensamider och tiobensamider

Info

Publication number
SE8302193L
SE8302193L SE8302193A SE8302193A SE8302193L SE 8302193 L SE8302193 L SE 8302193L SE 8302193 A SE8302193 A SE 8302193A SE 8302193 A SE8302193 A SE 8302193A SE 8302193 L SE8302193 L SE 8302193L
Authority
SE
Sweden
Prior art keywords
formula
substituted
thiobensamides
benzamides
pyrrolidinyl
Prior art date
Application number
SE8302193A
Other languages
English (en)
Other versions
SE8302193D0 (sv
SE431869B (sv
Inventor
Jr A D Cale
C A Leonard
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of SE8302193D0 publication Critical patent/SE8302193D0/sv
Publication of SE8302193L publication Critical patent/SE8302193L/sv
Publication of SE431869B publication Critical patent/SE431869B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Claims (1)

1. Patentkrav POrfarande for framstgllning av en forening med formeln 2 f'ar reagera med en bensoylklorid med formeln Cl-C dgr R2 betecknar vats, 3:gyre alkyl, lagre alkoxi, halogen, nitro, monoalkylamino, dialkylamino, merkaptometyl, aoetamido, sulfamoyl, cyano, Ivarvio nar R2 betecknar amino eller acetamido istgllet anvAndest 'svarande fbrening innehallande en nitrogrupp sedan utsattes Zr- hydroxi, bensyloxi, trifluormetyl,kannetecknat av att en forening med formelnkatalytisk hydrering till en aminogrupp och eventuollt acyleras till onskad acetaminogrupp.
SE8302193A 1972-04-03 1983-04-19 Forfarande for framstellning av n-(1-cyklohexyl-3-pyrrolidinyl)-bensamider med antiemetisk verkan SE431869B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24084072A 1972-04-03 1972-04-03
US34041773A 1973-03-12 1973-03-12

Publications (3)

Publication Number Publication Date
SE8302193D0 SE8302193D0 (sv) 1983-04-19
SE8302193L true SE8302193L (sv) 1983-04-19
SE431869B SE431869B (sv) 1984-03-05

Family

ID=26933765

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7304619A SE402102B (sv) 1972-04-03 1973-04-02 Forfarande for framstellning av 4-amino-n-(1-cyklohexyl-3-pyrrolidinyl)-n-alkyl-bensamider, med verdefulla terapeutiska egenskaper
SE7711953A SE431868B (sv) 1972-04-03 1977-10-24 Forfarande for framstellning av n-(1-cyklohexyl-3-pyrrolidinyl)-bensamider med antiemetisk verkan
SE8302193A SE431869B (sv) 1972-04-03 1983-04-19 Forfarande for framstellning av n-(1-cyklohexyl-3-pyrrolidinyl)-bensamider med antiemetisk verkan

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SE7304619A SE402102B (sv) 1972-04-03 1973-04-02 Forfarande for framstellning av 4-amino-n-(1-cyklohexyl-3-pyrrolidinyl)-n-alkyl-bensamider, med verdefulla terapeutiska egenskaper
SE7711953A SE431868B (sv) 1972-04-03 1977-10-24 Forfarande for framstellning av n-(1-cyklohexyl-3-pyrrolidinyl)-bensamider med antiemetisk verkan

Country Status (9)

Country Link
JP (4) JPS5620312B2 (sv)
CA (1) CA999003A (sv)
CH (1) CH580582A5 (sv)
DK (1) DK138491B (sv)
ES (1) ES413260A1 (sv)
NL (1) NL178318C (sv)
NO (1) NO142077C (sv)
PH (1) PH15259A (sv)
SE (3) SE402102B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA732296B (en) * 1972-04-03 1974-11-27 Robins Co Inc A H Method for controlling emesis with n-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides
JPS5423113Y2 (sv) * 1974-10-08 1979-08-09
JPS5925784B2 (ja) * 1975-12-17 1984-06-21 山之内製薬株式会社 シンキナカルボンサンアミドユウドウタイノセイホウ
JPS5232815U (sv) * 1975-08-28 1977-03-08
JPS5925785B2 (ja) * 1976-01-01 1984-06-21 山之内製薬株式会社 新規なカルボン酸アミド誘導体
JPS5522699A (en) * 1979-08-10 1980-02-18 Yamanouchi Pharmaceut Co Ltd Novel 3-amino-1-benzylpyrrolidine derivative
JPS6316492U (sv) * 1986-07-18 1988-02-03
AU2351895A (en) * 1994-04-28 1995-11-29 Yamanouchi Pharmaceutical Co., Ltd. N-(3-pyrrolidinyl)benzamide derivative
EA010027B1 (ru) 2002-11-27 2008-06-30 Инсайт Корпорейшн Производные 3-аминопирролидина в качестве модуляторов рецепторов хемокинов

Also Published As

Publication number Publication date
CH580582A5 (sv) 1976-10-15
CA999003A (en) 1976-10-26
DE2316644B2 (de) 1977-04-28
ES413260A1 (es) 1976-05-16
DK138491B (da) 1978-09-18
NO142077C (no) 1980-06-25
JPS5069066A (sv) 1975-06-09
JPS5182261A (en) 1976-07-19
JPS5527905B2 (sv) 1980-07-24
JPS4913165A (sv) 1974-02-05
DK138491C (sv) 1979-04-09
NL7304557A (sv) 1973-10-05
SE7711953L (sv) 1977-10-24
NL178318C (nl) 1986-03-03
SE8302193D0 (sv) 1983-04-19
SE431869B (sv) 1984-03-05
DE2316644A1 (de) 1973-10-18
JPS5620312B2 (sv) 1981-05-13
NL178318B (nl) 1985-10-01
JPS5069067A (sv) 1975-06-09
SE431868B (sv) 1984-03-05
PH15259A (en) 1982-11-02
NO142077B (no) 1980-03-17
SE402102B (sv) 1978-06-19

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