FR2228064A1 - 4-amino-2,6-dihydroxy-(di or tri-alkoxy)-benzyl-pyrimidines - and derivs - intermediates for pharmaceuticals - Google Patents

4-amino-2,6-dihydroxy-(di or tri-alkoxy)-benzyl-pyrimidines - and derivs - intermediates for pharmaceuticals

Info

Publication number
FR2228064A1
FR2228064A1 FR7404397A FR7404397A FR2228064A1 FR 2228064 A1 FR2228064 A1 FR 2228064A1 FR 7404397 A FR7404397 A FR 7404397A FR 7404397 A FR7404397 A FR 7404397A FR 2228064 A1 FR2228064 A1 FR 2228064A1
Authority
FR
France
Prior art keywords
derivs
pyrimidines
dihydroxy
pharmaceuticals
intermediates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7404397A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SOCECHIM
Original Assignee
SOCECHIM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SOCECHIM filed Critical SOCECHIM
Publication of FR2228064A1 publication Critical patent/FR2228064A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Title cpds. are of formula (where n = 2 or 3 and R = lower (pref. 1-4C) alkyl). They may be prepd. by reacting alkylbenzylmalonate derivs. of formula (where R1 = lower (pref. 1-4C) alkyl) with guaidine, and may be halogenated to give the corresp. dihalopyrimidines, which are inters. for pharmaceutically active 2,4-diamino-6-halo-pyrimidine derivs.
FR7404397A 1973-04-26 1974-02-08 4-amino-2,6-dihydroxy-(di or tri-alkoxy)-benzyl-pyrimidines - and derivs - intermediates for pharmaceuticals Withdrawn FR2228064A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE130414A BE798724A (en) 1973-04-26 1973-04-26 NEW CHEMICAL COMPOUNDS

Publications (1)

Publication Number Publication Date
FR2228064A1 true FR2228064A1 (en) 1974-11-29

Family

ID=3841884

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7404397A Withdrawn FR2228064A1 (en) 1973-04-26 1974-02-08 4-amino-2,6-dihydroxy-(di or tri-alkoxy)-benzyl-pyrimidines - and derivs - intermediates for pharmaceuticals

Country Status (8)

Country Link
JP (1) JPS5052076A (en)
AT (1) AT338792B (en)
BE (1) BE798724A (en)
CH (1) CH584693A5 (en)
DD (2) DD113540A5 (en)
DE (1) DE2352107A1 (en)
FR (1) FR2228064A1 (en)
HU (1) HU168987B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422648A1 (en) * 1977-11-10 1979-11-09 Hoffmann La Roche NEWS 2,4-DIAMINO-5-BENZYL-6-HALOGENOPYRIMIDINES

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2717516C3 (en) * 1977-04-20 1982-08-12 Wolfgang Dr. 8091 Ramerberg Holz Motorhome from a bus vehicle
WO1985002182A1 (en) * 1983-11-15 1985-05-23 Ethyl Corporation Process for preparing substituted benzyl malonic acid esters
GB9610320D0 (en) * 1996-05-17 1996-07-24 Zeneca Ltd Chemical process

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422648A1 (en) * 1977-11-10 1979-11-09 Hoffmann La Roche NEWS 2,4-DIAMINO-5-BENZYL-6-HALOGENOPYRIMIDINES

Also Published As

Publication number Publication date
CH584693A5 (en) 1977-02-15
DE2352107A1 (en) 1974-11-14
ATA877373A (en) 1977-01-15
AT338792B (en) 1977-09-12
HU168987B (en) 1976-08-28
BE798724A (en) 1973-08-16
DD113540A5 (en) 1975-06-12
JPS5052076A (en) 1975-05-09
DD118642A5 (en) 1976-03-12

Similar Documents

Publication Publication Date Title
IT1024532B (en) PRODUCTION BY THE SE LECTIVE ELIMINATION OF NITROGEN OXIDES FROM EXHAUST GAS
IE39078L (en) Substituted 1,3,5 - triazines.
IE41383L (en) Piperidinylimidazolinone derivatives
IE34794L (en) Sulphur-containing 1, 4-dihydropyridine derivatives
IE34742B1 (en) Cyano-phenyl-1,4-dihydropyridine derivatives
IE41440L (en) Thiatetracyclines
FR2228064A1 (en) 4-amino-2,6-dihydroxy-(di or tri-alkoxy)-benzyl-pyrimidines - and derivs - intermediates for pharmaceuticals
GB1447462A (en) Alpha-thiolincosaminides and the preparation thereof
ZA754685B (en) 9.3",4"-triacyl ester of the antibiotic sf-837 m1 substance and the production thereof
GB1428926A (en) Ring-halogen-free substituted triazines as bleach activators
NL7405636A (en) 4-amino-2,6-dihydroxy-(di or tri-alkoxy)-benzyl-pyrimidines - and derivs - intermediates for pharmaceuticals
CA974256A (en) Production of n,n,n',n'-tetraacetylethylenediamine
ES440055A1 (en) 19,20-Bis-nor-prostenoic acids as hypolipemic compounds
ES445144A1 (en) Indolobenzazepine derivatives
ES424946A1 (en) Imidazole derivatives
IE39049L (en) 1, 4-dihydroquinolines.
IE40805B1 (en) Sulphonylurea derivatives
JPS52130822A (en) Tetrachloronaphthalic imide derivative and its production
IE41670L (en) Diisocyanato-diketenes.
GB1027891A (en) Esters of dianhydro-hexitols
PH9783A (en) Process for the preparation of n-(n',n'-dilower-alkylaminoloweralkylene)-4-amino-2,5-disubstituted benzamides
SU673336A1 (en) Arrangement for stage-wise toppling of articles, such as roll-stand bearing units
FR2210186A5 (en) Halogenated ureidophenyl carbamates - herbicides, by reacting corresp. halophenols and isocyanates
FR2231656A1 (en) Substd phenoxy acetates - as water sol herbicides
FR2152361A1 (en) Bis (aminoalkylsulfamoyl) anthraquinones - useful as antiviral agents

Legal Events

Date Code Title Description
ST Notification of lapse