IE33862B1 - Thiepin and oxepin derivatives,processes for their production and medicaments containing same - Google Patents
Thiepin and oxepin derivatives,processes for their production and medicaments containing sameInfo
- Publication number
- IE33862B1 IE33862B1 IE1598/69A IE159869A IE33862B1 IE 33862 B1 IE33862 B1 IE 33862B1 IE 1598/69 A IE1598/69 A IE 1598/69A IE 159869 A IE159869 A IE 159869A IE 33862 B1 IE33862 B1 IE 33862B1
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- compound
- pharmaceutically acceptable
- acid addition
- acceptable acid
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- ATYBXHSAIOKLMG-UHFFFAOYSA-N oxepin Chemical class O1C=CC=CC=C1 ATYBXHSAIOKLMG-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 239000002253 acid Substances 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 101100037762 Caenorhabditis elegans rnh-2 gene Proteins 0.000 abstract 1
- OWYWGLHRNBIFJP-UHFFFAOYSA-N Ipazine Chemical compound CCN(CC)C1=NC(Cl)=NC(NC(C)C)=N1 OWYWGLHRNBIFJP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- APMCUORPNXHBQK-UHFFFAOYSA-N benzo[c][1]benzoxepine Chemical class O1C=C2C=CC=CC2=CC2=CC=CC=C12 APMCUORPNXHBQK-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000003874 central nervous system depressant Substances 0.000 abstract 1
- 150000008510 dibenzothiepins Chemical class 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 125000003754 ethoxycarbonyl group Chemical group C(=O)(OCC)* 0.000 abstract 1
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/14—[b,f]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/14—[b,f]-condensed
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B3/00—Measuring instruments characterised by the use of mechanical techniques
- G01B3/02—Rulers with scales or marks for direct reading
- G01B3/04—Rulers with scales or marks for direct reading rigid
- G01B3/06—Rulers with scales or marks for direct reading rigid folding
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- General Physics & Mathematics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1764468A CH501007A (de) | 1968-11-27 | 1968-11-27 | Verfahren zur Herstellung von neuen Thiepin- und Oxepinderivaten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE33862L IE33862L (en) | 1970-05-27 |
| IE33862B1 true IE33862B1 (en) | 1974-11-27 |
Family
ID=4426992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1598/69A IE33862B1 (en) | 1968-11-27 | 1969-11-26 | Thiepin and oxepin derivatives,processes for their production and medicaments containing same |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US3636045A (en, 2012) |
| AT (2) | AT294104B (en, 2012) |
| BE (1) | BE742299A (en, 2012) |
| BR (1) | BR6914562D0 (en, 2012) |
| CH (2) | CH501007A (en, 2012) |
| CS (2) | CS166246B2 (en, 2012) |
| DE (2) | DE1965969C3 (en, 2012) |
| DK (1) | DK130214B (en, 2012) |
| FI (1) | FI50628C (en, 2012) |
| FR (1) | FR2024380B1 (en, 2012) |
| GB (2) | GB1297386A (en, 2012) |
| HK (1) | HK22376A (en, 2012) |
| IE (1) | IE33862B1 (en, 2012) |
| IL (2) | IL33435A (en, 2012) |
| KE (1) | KE2608A (en, 2012) |
| MY (1) | MY7600094A (en, 2012) |
| NL (1) | NL164284C (en, 2012) |
| NO (1) | NO127401B (en, 2012) |
| PL (2) | PL80742B1 (en, 2012) |
| SE (2) | SE374371B (en, 2012) |
| YU (2) | YU33872B (en, 2012) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH532038A (de) * | 1970-05-25 | 1972-12-31 | Ciba Geigy Ag | Verfahren zur Herstellung von neuen Cycloheptenderivaten |
| US4112110A (en) * | 1974-02-22 | 1978-09-05 | Ciba-Geigy Corporation | Oxygenated azatetracyclic compounds |
| SE7504508L (sv) * | 1974-05-10 | 1975-11-11 | Ciba Geigy Ag | Nya heterocykliska s-imino-s-oxider. |
| NL7414038A (nl) * | 1974-10-28 | 1976-05-03 | Akzo Nv | Nieuwe tetracyclische pyrrolidino derivaten. |
| US4154836A (en) * | 1976-05-24 | 1979-05-15 | Akzona Incorporated | Tension reducing 1,2,3,4,4a,13b-hexahydro-dibenz[2,3;6,7]oxepino[4,5-c]pyridines |
| US4271179A (en) * | 1976-05-24 | 1981-06-02 | Akzona Incorporated | 1,2,3,3a,8,12b-Hexahydro-dibenzo[1,2;5,6]cyclohepta[3,4-C]pyrroles and pharmaceutical use thereof |
| NL7605526A (nl) * | 1976-05-24 | 1977-11-28 | Akzo Nv | Nieuwe tetracyclische derivaten. |
| US4271177A (en) * | 1976-05-24 | 1981-06-02 | Akzona Incorporated | 2,3,3a,12b-Tetrahydro-1H-dibenzo[2,3;6,7]thiepino[4,5-c]pyrroles and pharmaceutical use thereof |
| US4177275A (en) * | 1976-05-24 | 1979-12-04 | Akzona Inc. | Tension reducing 2,3,4,4a,9,13b-hexahydro-1H-dibenzo[b,f]pyrido[3,4-d]azepine derivatives |
| EP0007450A1 (de) * | 1978-07-07 | 1980-02-06 | Ciba-Geigy Ag | Azatetracyclische Carbonitrile, ihre Herstellung, pharmazeutische Präparate, die diese enthalten und deren Verwendung |
| EP0030916B1 (de) * | 1979-12-10 | 1984-08-29 | Ciba-Geigy Ag | Azatetracyclische Carbonitrile |
| DE202009001592U1 (de) | 2009-02-09 | 2009-08-27 | Fidan, Cetin | Zollstock mit integrierter Beleuchtung |
| CN117304166A (zh) * | 2023-09-20 | 2023-12-29 | 贵州农业职业学院 | 一种新的扎托布洛芬衍生物及其制备方法和应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH440318A (de) * | 1964-11-03 | 1967-07-31 | Geigy Ag J R | Verfahren zur Herstellung von neuen Thiepin- und Oxepinderivaten |
-
1968
- 1968-11-27 CH CH1764468A patent/CH501007A/de not_active IP Right Cessation
- 1968-11-27 CH CH1048570A patent/CH507232A/de not_active IP Right Cessation
-
1969
- 1969-11-19 US US878175A patent/US3636045A/en not_active Expired - Lifetime
- 1969-11-20 NL NL6917506.A patent/NL164284C/xx not_active IP Right Cessation
- 1969-11-20 SE SE7007890A patent/SE374371B/xx unknown
- 1969-11-20 FI FI693352A patent/FI50628C/fi active
- 1969-11-20 SE SE15969/69A patent/SE343577B/xx unknown
- 1969-11-20 DK DK614969AA patent/DK130214B/da unknown
- 1969-11-20 NO NO04601/69A patent/NO127401B/no unknown
- 1969-11-24 CS CS7724A patent/CS166246B2/cs unknown
- 1969-11-24 CS CS6275A patent/CS166247B2/cs unknown
- 1969-11-26 GB GB5784969A patent/GB1297386A/en not_active Expired
- 1969-11-26 IL IL33435A patent/IL33435A/xx unknown
- 1969-11-26 AT AT1104769A patent/AT294104B/de not_active IP Right Cessation
- 1969-11-26 PL PL1969142308A patent/PL80742B1/pl unknown
- 1969-11-26 AT AT643570A patent/AT293402B/de not_active IP Right Cessation
- 1969-11-26 PL PL1969137136A patent/PL80395B1/pl unknown
- 1969-11-26 IE IE1598/69A patent/IE33862B1/xx unknown
- 1969-11-26 BR BR214562/69A patent/BR6914562D0/pt unknown
- 1969-11-26 GB GB2484172A patent/GB1297387A/en not_active Expired
- 1969-11-26 DE DE1965969A patent/DE1965969C3/de not_active Expired
- 1969-11-26 DE DE1959405A patent/DE1959405C3/de not_active Expired
- 1969-11-26 YU YU2963/69A patent/YU33872B/xx unknown
- 1969-11-26 IL IL40861A patent/IL40861A/en unknown
- 1969-11-27 BE BE742299A patent/BE742299A/xx unknown
- 1969-11-27 FR FR696940933A patent/FR2024380B1/fr not_active Expired
-
1970
- 1970-08-04 YU YU1980/70A patent/YU34042B/xx unknown
-
1976
- 1976-03-12 KE KE2608*UA patent/KE2608A/xx unknown
- 1976-04-14 HK HK223/76*UA patent/HK22376A/xx unknown
- 1976-12-30 MY MY94/76A patent/MY7600094A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IE33862B1 (en) | Thiepin and oxepin derivatives,processes for their production and medicaments containing same | |
| ES357247A1 (es) | Procedimiento para la preparacion de un nuevo derivado de tetrahidroacepina. | |
| GB1488692A (en) | Pyrazolo(3,4,6)quinolines | |
| GB1433701A (en) | 5-6-benzene ring substituted benzimidazole-2-carbamate derivative having anthelmintic activity apparatus | |
| GB1411583A (en) | Aminophenyl-substituted alkyl-heterocyclic derivatives and processes for producing them | |
| GB1531963A (en) | Pyrido(1,2alpha)pyrimidine derivatives | |
| GB1228736A (en, 2012) | ||
| IE32509B1 (en) | Naphthacene derivatives | |
| GB1363195A (en) | Propenylamine derivatives and process for the production thereof | |
| IE35879B1 (en) | Penicillanic acid derivatives | |
| GB1529403A (en) | Isoxazole derivative | |
| GB1120186A (en) | Cyclohexene amino acid derivatives and process for their preparation | |
| IE39770B1 (en) | Thiazole derivatives | |
| GB1263116A (en) | Chloramphenicol and thiamphenicol derivatives | |
| GB1384523A (en) | Oxime derivatives and their preparation | |
| GB1339010A (en) | Tetrazolyl-anthraquinone derivatives | |
| IE32859L (en) | Penicilloic acid derivatives. | |
| GB1436502A (en) | Amide derivatives of 3-benzoylphenyl-alkanoic acids | |
| GB1254270A (en) | Benzoxazepine derivatives | |
| GB1426200A (en) | Nahpthyridine derivatives | |
| GB1369888A (en) | Substituted amidines | |
| GB1417822A (en) | 4,8-dimethoxy-furo 3,2-f- benzoxazol-2-yl acethydroxamic acid its process of preparation and its therapeutic preparation | |
| GB1322069A (en) | Aminoalkanoylaminocyclohexane derivatives | |
| GB1440670A (en) | Lactam derivatives | |
| GB1420560A (en) | S-i-v-benzo-1,2,4-thiadiazines |