IE32639B1 - Indole derivatives and a process for the production thereof - Google Patents
Indole derivatives and a process for the production thereofInfo
- Publication number
- IE32639B1 IE32639B1 IE156/69A IE15669A IE32639B1 IE 32639 B1 IE32639 B1 IE 32639B1 IE 156/69 A IE156/69 A IE 156/69A IE 15669 A IE15669 A IE 15669A IE 32639 B1 IE32639 B1 IE 32639B1
- Authority
- IE
- Ireland
- Prior art keywords
- compounds
- laevorotatory
- possibly
- substituted
- methyl
- Prior art date
Links
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
- NLMQHXUGJIAKTH-UHFFFAOYSA-N 4-hydroxyindole Chemical compound OC1=CC=CC2=C1C=CN2 NLMQHXUGJIAKTH-UHFFFAOYSA-N 0.000 abstract 1
- 101100294106 Caenorhabditis elegans nhr-3 gene Proteins 0.000 abstract 1
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 abstract 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical class ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- GKIPXFAANLTWBM-UHFFFAOYSA-N epibromohydrin Chemical compound BrCC1CO1 GKIPXFAANLTWBM-UHFFFAOYSA-N 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE1664/71A IE32640B1 (en) | 1968-02-09 | 1969-02-06 | An indole derivative and a process for the production thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH198768A CH495983A (de) | 1968-02-09 | 1968-02-09 | Verfahren zur Herstellung von linksdrehendem 4-(2-Hydroxy-3-isopropylaminopropoxy)indol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IE32639B1 true IE32639B1 (en) | 1973-10-17 |
Family
ID=4223253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE156/69A IE32639B1 (en) | 1968-02-09 | 1969-02-06 | Indole derivatives and a process for the production thereof |
Country Status (14)
| Country | Link |
|---|---|
| AT (1) | AT299188B (en)) |
| BE (1) | BE728142A (en)) |
| BR (1) | BR6906200D0 (en)) |
| CH (1) | CH495983A (en)) |
| DE (1) | DE1905881C2 (en)) |
| DK (1) | DK119110B (en)) |
| FI (1) | FI50972C (en)) |
| FR (2) | FR1598040A (en)) |
| GB (2) | GB1252399A (en)) |
| IE (1) | IE32639B1 (en)) |
| IL (1) | IL31570A (en)) |
| NL (1) | NL6900797A (en)) |
| NO (1) | NO125590B (en)) |
| SE (1) | SE340621B (en)) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4182911A (en) | 1973-11-09 | 1980-01-08 | Imperial Chemical Industries Limited | Optically-active 1-aryloxy-2-propanol intermediates of (S)-absolute configuration |
| DE2454198C2 (de) * | 1974-11-15 | 1986-08-07 | Knoll Ag, 6700 Ludwigshafen | Isochinolin-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel |
| CA1116598A (en) * | 1977-07-13 | 1982-01-19 | William T. Comer | 3-indolyl-tertiary butylaminopropanols |
| DE2905053A1 (de) * | 1979-02-08 | 1980-08-14 | Schering Ag | Verfahren zur herstellung von 1-(2-methylindol-4-yloxy)-2.3-epoxypropan |
| DE3030047A1 (de) * | 1980-08-08 | 1982-03-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3029980A1 (de) * | 1980-08-08 | 1982-03-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | Indolderivate und verfahren zu ihrer herstellung |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1129072A (en) * | 1966-02-01 | 1968-10-02 | Ici Ltd | Benzofuran and indole derivatives |
| NL131726C (en)) * | 1965-02-01 |
-
1968
- 1968-02-09 CH CH198768A patent/CH495983A/de not_active IP Right Cessation
- 1968-12-23 FR FR1598040D patent/FR1598040A/fr not_active Expired
-
1969
- 1969-01-13 GB GB1252399D patent/GB1252399A/en not_active Expired
- 1969-01-13 GB GB1251716D patent/GB1251716A/en not_active Expired
- 1969-01-17 DK DK26869AA patent/DK119110B/da unknown
- 1969-01-17 NL NL6900797A patent/NL6900797A/xx unknown
- 1969-01-17 SE SE00616/69A patent/SE340621B/xx unknown
- 1969-01-20 NO NO0209/69A patent/NO125590B/no unknown
- 1969-01-20 FI FI690158A patent/FI50972C/fi active
- 1969-02-06 DE DE1905881A patent/DE1905881C2/de not_active Expired
- 1969-02-06 IE IE156/69A patent/IE32639B1/xx unknown
- 1969-02-07 AT AT128169A patent/AT299188B/de not_active IP Right Cessation
- 1969-02-07 BR BR206200/69A patent/BR6906200D0/pt unknown
- 1969-02-07 BE BE728142D patent/BE728142A/xx not_active IP Right Cessation
- 1969-02-07 IL IL31570A patent/IL31570A/en unknown
- 1969-03-18 FR FR183290A patent/FR8067M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI50972C (fi) | 1976-09-10 |
| FR1598040A (en)) | 1970-06-29 |
| SE340621B (en)) | 1971-11-29 |
| AT299188B (de) | 1972-06-12 |
| IL31570A0 (en) | 1969-11-12 |
| NO125590B (en)) | 1972-10-02 |
| CH495983A (de) | 1970-09-15 |
| NL6900797A (en)) | 1969-08-12 |
| DK119110B (da) | 1970-11-16 |
| FR8067M (en)) | 1970-07-06 |
| IL31570A (en) | 1972-03-28 |
| GB1251716A (en)) | 1971-10-27 |
| BR6906200D0 (pt) | 1973-02-27 |
| FI50972B (en)) | 1976-05-31 |
| GB1252399A (en)) | 1971-11-03 |
| DE1905881A1 (de) | 1969-09-25 |
| DE1905881C2 (de) | 1984-03-08 |
| BE728142A (en)) | 1969-08-07 |
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