ID28494A - INHIBITOR FAKTOR VIIa - Google Patents

INHIBITOR FAKTOR VIIa

Info

Publication number
ID28494A
ID28494A IDW20010598A ID20010598A ID28494A ID 28494 A ID28494 A ID 28494A ID W20010598 A IDW20010598 A ID W20010598A ID 20010598 A ID20010598 A ID 20010598A ID 28494 A ID28494 A ID 28494A
Authority
ID
Indonesia
Prior art keywords
factor viia
inhibitor factor
inhibitor
viia
factor
Prior art date
Application number
IDW20010598A
Other languages
English (en)
Indonesian (id)
Inventor
Safar Pavel
Safarova Alena
Wildgoose Peter
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of ID28494A publication Critical patent/ID28494A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1019Tetrapeptides with the first amino acid being basic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0815Tripeptides with the first amino acid being basic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/105831Protein or peptide standard or control [e.g., hemoglobin, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IDW20010598A 1998-09-15 1999-09-02 INHIBITOR FAKTOR VIIa ID28494A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98117506A EP0987274A1 (en) 1998-09-15 1998-09-15 Factor VIIa Inhibitors

Publications (1)

Publication Number Publication Date
ID28494A true ID28494A (id) 2001-05-31

Family

ID=8232644

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20010598A ID28494A (id) 1998-09-15 1999-09-02 INHIBITOR FAKTOR VIIa

Country Status (25)

Country Link
US (1) US6287794B1 (cs)
EP (2) EP0987274A1 (cs)
JP (1) JP4537581B2 (cs)
KR (1) KR100665490B1 (cs)
CN (1) CN1203087C (cs)
AR (1) AR027814A1 (cs)
AT (1) ATE460424T1 (cs)
AU (1) AU760580B2 (cs)
BR (1) BR9913742A (cs)
CA (1) CA2344048A1 (cs)
CZ (1) CZ300249B6 (cs)
DE (1) DE69942123D1 (cs)
HK (1) HK1040253B (cs)
HU (1) HUP0103851A3 (cs)
ID (1) ID28494A (cs)
IL (2) IL141415A0 (cs)
MY (1) MY125150A (cs)
NO (1) NO328523B1 (cs)
NZ (1) NZ510509A (cs)
PL (1) PL203227B1 (cs)
RU (1) RU2223967C2 (cs)
TR (1) TR200100766T2 (cs)
TW (1) TW576839B (cs)
WO (1) WO2000015658A1 (cs)
ZA (1) ZA200101861B (cs)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0987274A1 (en) * 1998-09-15 2000-03-22 Hoechst Marion Roussel Deutschland GmbH Factor VIIa Inhibitors
PL350042A1 (en) 1999-01-13 2002-10-21 Genentech Inc Serine protease inhibitors
EP1059302A1 (en) * 1999-06-08 2000-12-13 Aventis Pharma Deutschland GmbH Factor VIIa inhibitors
DE60045638D1 (de) * 1999-10-01 2011-03-31 Chugai Pharmaceutical Co Ltd Vermeidung und behandlung von krankheiten, die mit der blutgerinnung in zusammenhang stehen
EP1095933A1 (en) 1999-10-30 2001-05-02 Aventis Pharma Deutschland GmbH Novel N-guanidinoalkylamides, their preparation, their use, and pharmaceutical preparations comprising them
EP1162194A1 (en) * 2000-06-06 2001-12-12 Aventis Pharma Deutschland GmbH Factor VIIa inhibitory (thio)urea derivatives, their preparation and their use
GB0014134D0 (en) * 2000-06-10 2000-08-02 Astrazeneca Ab Combination therapy
IL155202A0 (en) 2000-10-20 2003-11-23 Biocryst Pharm Inc Biaryl compounds as serine protease inhibitors
JP4274522B2 (ja) 2000-12-06 2009-06-10 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Xa因子阻害剤としてのグアニジンおよびアミジン誘導体
EP1364960A4 (en) 2001-02-02 2005-05-18 Chugai Pharmaceutical Co Ltd PEPTIDE DERIVATIVES
EP1270551A1 (en) 2001-06-26 2003-01-02 Aventis Pharma Deutschland GmbH Urea derivatives with antiproteolytic activity
EP1314733A1 (en) 2001-11-22 2003-05-28 Aventis Pharma Deutschland GmbH Indole-2-carboxamides as factor Xa inhibitors
AU2003290663A1 (en) * 2002-11-13 2004-06-03 Haematologic Technologies, Inc. Assay for tissue factor and factor viia
US7358268B2 (en) 2002-12-04 2008-04-15 Sanofi-Aventis Deutschland Gmbh Imidazole derivatives as factor Xa inhibitors
US7429581B2 (en) 2002-12-23 2008-09-30 Sanofi-Aventis Deutschland Gmbh Pyrazole-derivatives as factor Xa inhibitors
US7223780B2 (en) 2003-05-19 2007-05-29 Sanofi-Aventis Deutschland Gmbh Triazole-derivatives as blood clotting enzyme factor Xa inhibitors
US7317027B2 (en) 2003-05-19 2008-01-08 Sanofi-Aventis Deutschland Gmbh Azaindole-derivatives as factor Xa inhibitors
US7741341B2 (en) 2003-05-19 2010-06-22 Sanofi-Aventis Deutschland Gmbh Benzimidazole-derivatives as factor Xa inhibitors
EP1479677A1 (en) * 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH New indole derivatives as factor xa inhibitors
EP1479680A1 (en) 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH Azaindole derivatives as Factor Xa inhibitors
EP1479675A1 (en) 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH Indazole-derivatives as factor Xa inhibitors
JP2007505160A (ja) 2003-05-20 2007-03-08 ジェネンテック・インコーポレーテッド 第VIIa因子のアシルスルファミド阻害剤
CA2525713A1 (en) 2003-05-20 2004-12-29 Genentech, Inc. Benzofuran inhibitors of factor viia
EP1568698A1 (en) 2004-02-27 2005-08-31 Aventis Pharma Deutschland GmbH Pyrrole-derivatives as factor Xa inhibitors
JP5232470B2 (ja) * 2004-05-27 2013-07-10 バクスター・インターナショナル・インコーポレイテッド 硫酸化多糖を用いて出血性疾患を処置するための方法
WO2008107362A2 (en) * 2007-03-07 2008-09-12 Novo Nordisk Health Care Ag Stabiliser and inhibitors of factor vii
AU2008274655A1 (en) 2007-07-10 2009-01-15 Sanofi-Aventis Malonamide derivatives with antithrombotic activity
EP2235042A1 (en) * 2008-01-23 2010-10-06 Novo Nordisk Health Care AG New blood coagulation factor inhibitors
TR201807926T4 (tr) 2011-02-04 2018-06-21 Octapharma Ag Koagülasyon faktörlerinin çökeltme yoluyla etkisizleştirilmesine/çıkarılmasına yönelik usul.
EP3849583A1 (en) * 2018-09-11 2021-07-21 Anbition S.r.l. Peptides and medical uses thereof
CN112996528B (zh) * 2018-09-11 2025-01-07 安必圣有限责任公司 肽及其医学用途
DK3993876T3 (en) 2019-07-01 2024-12-02 Tonix Pharma Ltd Anti-cd154 antibodies and uses thereof
EP4274587A1 (en) 2021-01-06 2023-11-15 Tonix Pharma Limited Methods of inducing immune tolerance with modified anti-cd154 antibodies
GB202209228D0 (en) * 2022-06-23 2022-08-10 Univ Strathclyde Modified amino acids and uses thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023236A (en) * 1988-04-07 1991-06-11 Corvas, Inc. Factor VII/VIIA active site inhibitors
AU4338689A (en) * 1988-09-23 1990-04-18 Corvas, Inc. Peptidyl inhibitors of the initiation of coagulation
CA2008116C (en) * 1989-02-23 2001-11-20 Thomas Weller Glycine derivatives
US5190919A (en) * 1989-11-13 1993-03-02 Board Of Regents, The University Of Texas System Antihemostatic factor vii peptides
HU206372B (en) * 1990-09-03 1992-10-28 Richter Gedeon Vegyeszet Process for producing new oligopeptides which selectively inhibit proliferation of haemopoietic cells and pharmaceutical compositions comprising same
US5506134A (en) 1990-10-22 1996-04-09 Corvas International, Inc. Hypridoma and monoclonal antibody which inhibits blood coagulation tissue factor/factor VIIa complex
US5788965A (en) 1991-02-28 1998-08-04 Novo Nordisk A/S Modified factor VII
US5833982A (en) 1991-02-28 1998-11-10 Zymogenetics, Inc. Modified factor VII
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
WO1995000541A1 (en) * 1993-06-18 1995-01-05 Hafslund Nycomed A/S Factor vii-derived peptides
US5849510A (en) * 1994-04-26 1998-12-15 Selectide Corporation Factor Xa inhibitors
SI9520044B (sl) * 1994-04-26 2004-08-31 Aventis Pharmaceuticals Inc. Inhibitorji Xa faktorja
RU2097033C1 (ru) * 1994-09-30 1997-11-27 Московская государственная академия тонкой химической технологии им.М.В.Ломоносова Имидазолсодержащие ингибиторы катепсин g-индуцированной агрегации тромбоцитов
US5837684A (en) * 1995-06-07 1998-11-17 Nycomed Imaging As Peptides
PT892780E (pt) * 1996-02-22 2003-02-28 Bristol Myers Squibb Pharma Co Analogos de m-amidino fenilo como inibidores do factor xa
EP0987274A1 (en) * 1998-09-15 2000-03-22 Hoechst Marion Roussel Deutschland GmbH Factor VIIa Inhibitors

Also Published As

Publication number Publication date
WO2000015658A1 (en) 2000-03-23
PL346781A1 (en) 2002-02-25
IL141415A0 (en) 2002-03-10
DE69942123D1 (de) 2010-04-22
JP4537581B2 (ja) 2010-09-01
JP2002524571A (ja) 2002-08-06
NO20011293L (no) 2001-05-04
KR20010075130A (ko) 2001-08-09
ZA200101861B (en) 2001-10-22
AU760580B2 (en) 2003-05-15
AR027814A1 (es) 2003-04-16
EP0987274A1 (en) 2000-03-22
MY125150A (en) 2006-07-31
CN1318069A (zh) 2001-10-17
TR200100766T2 (tr) 2001-10-22
HK1040253A1 (en) 2002-05-31
AU5972399A (en) 2000-04-03
EP1114061A1 (en) 2001-07-11
NO328523B1 (no) 2010-03-08
HK1040253B (zh) 2005-09-02
US6287794B1 (en) 2001-09-11
IL141415A (en) 2006-09-05
CZ300249B6 (cs) 2009-04-01
HUP0103851A2 (hu) 2002-04-29
KR100665490B1 (ko) 2007-01-10
EP1114061B1 (en) 2010-03-10
NO20011293D0 (no) 2001-03-14
BR9913742A (pt) 2001-06-05
ATE460424T1 (de) 2010-03-15
TW576839B (en) 2004-02-21
CZ2001914A3 (en) 2001-06-13
CN1203087C (zh) 2005-05-25
RU2223967C2 (ru) 2004-02-20
NZ510509A (en) 2002-09-27
CA2344048A1 (en) 2000-03-23
PL203227B1 (pl) 2009-09-30
HUP0103851A3 (en) 2002-05-28

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