ID26665A - Antagonis vla-4 - Google Patents
Antagonis vla-4Info
- Publication number
- ID26665A ID26665A IDW20001404A ID20001404A ID26665A ID 26665 A ID26665 A ID 26665A ID W20001404 A IDW20001404 A ID W20001404A ID 20001404 A ID20001404 A ID 20001404A ID 26665 A ID26665 A ID 26665A
- Authority
- ID
- Indonesia
- Prior art keywords
- vla
- antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1233698A | 1998-01-23 | 1998-01-23 | |
US11072398P | 1998-12-03 | 1998-12-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
ID26665A true ID26665A (id) | 2001-01-25 |
Family
ID=26683440
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDW20001404A ID26665A (id) | 1998-01-23 | 1999-01-21 | Antagonis vla-4 |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1049665A1 (de) |
JP (1) | JP4564654B2 (de) |
KR (1) | KR20010034317A (de) |
CN (1) | CN1294576A (de) |
AU (1) | AU746174B2 (de) |
BR (1) | BR9907733A (de) |
CA (1) | CA2318639A1 (de) |
EE (1) | EE200000428A (de) |
HU (1) | HUP0100336A3 (de) |
ID (1) | ID26665A (de) |
IL (1) | IL137329A0 (de) |
NO (1) | NO20003694L (de) |
WO (1) | WO1999037605A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000043369A1 (en) * | 1999-01-22 | 2000-07-27 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by vla-4 |
DK1144388T3 (da) | 1999-01-22 | 2010-05-25 | Elan Pharm Inc | Acyl-derivater, som behandler VLA-4-relaterede lidelser |
US6436904B1 (en) | 1999-01-25 | 2002-08-20 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
JP2002538135A (ja) | 1999-03-01 | 2002-11-12 | エラン ファーマシューティカルズ,インコーポレイテッド | α4β7レセプターアンタゴニストとして有用なα−アミノ酢酸誘導体 |
EP1235793A2 (de) * | 1999-12-07 | 2002-09-04 | Novartis AG | Vla-4 integrin-antagonisten |
KR20020067050A (ko) * | 1999-12-28 | 2002-08-21 | 화이자 프로덕츠 인코포레이티드 | 염증성, 자기면역 및 호흡기 질환의 치료에 유용한브이엘에이-4 의존성 세포 결합의 비펩티드계 억제제 |
DE10019755A1 (de) * | 2000-04-20 | 2001-11-08 | Bayer Ag | Neue Aminoaryl/cycloalkylcarbonsäuren als Integrinantagonisten |
GB2369357A (en) * | 2000-10-09 | 2002-05-29 | Bayer Ag | Aliphatic, cyclic amino carboxylic acids as integrin antagonists |
GB2367816A (en) | 2000-10-09 | 2002-04-17 | Bayer Ag | Urea- and thiourea-containing derivatives of beta-amino acids |
GB2377933A (en) | 2001-07-06 | 2003-01-29 | Bayer Ag | Succinic acid derivatives useful as integrin antagonists |
TW200307671A (en) | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
TWI281470B (en) | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
TW200610754A (en) * | 2004-06-14 | 2006-04-01 | Daiichi Seiyaku Co | Vla-4 inhibitor |
GB0523576D0 (en) * | 2005-11-18 | 2005-12-28 | Theradeas Ltd | Drug composition and its use in therapy |
AU2008219007A1 (en) | 2007-02-20 | 2008-08-28 | Merrimack Pharmaceuticals, Inc. | Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist |
EA022201B1 (ru) | 2008-04-11 | 2015-11-30 | Мерримак Фармасьютикалз, Инк. | Агент, способный связываться с опухолевой клеткой, содержащий линкер на основе hsa, и его применение |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6306840B1 (en) * | 1995-01-23 | 2001-10-23 | Biogen, Inc. | Cell adhesion inhibitors |
TR200001947T2 (tr) * | 1997-12-23 | 2001-01-22 | Aventis Pharma Limited | İkame edilmiş B-Alaninler. |
-
1999
- 1999-01-21 ID IDW20001404A patent/ID26665A/id unknown
- 1999-01-21 EE EEP200000428A patent/EE200000428A/xx unknown
- 1999-01-21 EP EP99908811A patent/EP1049665A1/de not_active Withdrawn
- 1999-01-21 WO PCT/EP1999/000384 patent/WO1999037605A1/en not_active Application Discontinuation
- 1999-01-21 CA CA002318639A patent/CA2318639A1/en not_active Abandoned
- 1999-01-21 IL IL13732999A patent/IL137329A0/xx unknown
- 1999-01-21 KR KR1020007008039A patent/KR20010034317A/ko not_active Application Discontinuation
- 1999-01-21 JP JP2000528529A patent/JP4564654B2/ja not_active Expired - Fee Related
- 1999-01-21 HU HU0100336A patent/HUP0100336A3/hu unknown
- 1999-01-21 CN CN99803780A patent/CN1294576A/zh active Pending
- 1999-01-21 BR BR9907733-7A patent/BR9907733A/pt not_active IP Right Cessation
- 1999-01-21 AU AU28292/99A patent/AU746174B2/en not_active Ceased
-
2000
- 2000-07-19 NO NO20003694A patent/NO20003694L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20010034317A (ko) | 2001-04-25 |
EE200000428A (et) | 2001-12-17 |
BR9907733A (pt) | 2000-10-17 |
NO20003694L (no) | 2000-09-20 |
AU2829299A (en) | 1999-08-09 |
WO1999037605A1 (en) | 1999-07-29 |
JP2002501039A (ja) | 2002-01-15 |
NO20003694D0 (no) | 2000-07-19 |
CN1294576A (zh) | 2001-05-09 |
HUP0100336A2 (hu) | 2001-07-30 |
CA2318639A1 (en) | 1999-07-29 |
IL137329A0 (en) | 2001-07-24 |
EP1049665A1 (de) | 2000-11-08 |
JP4564654B2 (ja) | 2010-10-20 |
HUP0100336A3 (en) | 2002-11-28 |
AU746174B2 (en) | 2002-04-18 |
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