IL137329A0 - Vla-4 antagonists - Google Patents
Vla-4 antagonistsInfo
- Publication number
- IL137329A0 IL137329A0 IL13732999A IL13732999A IL137329A0 IL 137329 A0 IL137329 A0 IL 137329A0 IL 13732999 A IL13732999 A IL 13732999A IL 13732999 A IL13732999 A IL 13732999A IL 137329 A0 IL137329 A0 IL 137329A0
- Authority
- IL
- Israel
- Prior art keywords
- vla
- antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1233698A | 1998-01-23 | 1998-01-23 | |
| US11072398P | 1998-12-03 | 1998-12-03 | |
| PCT/EP1999/000384 WO1999037605A1 (en) | 1998-01-23 | 1999-01-21 | Vla-4 antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL137329A0 true IL137329A0 (en) | 2001-07-24 |
Family
ID=26683440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13732999A IL137329A0 (en) | 1998-01-23 | 1999-01-21 | Vla-4 antagonists |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1049665A1 (xx) |
| JP (1) | JP4564654B2 (xx) |
| KR (1) | KR20010034317A (xx) |
| CN (1) | CN1294576A (xx) |
| AU (1) | AU746174B2 (xx) |
| BR (1) | BR9907733A (xx) |
| CA (1) | CA2318639A1 (xx) |
| EE (1) | EE200000428A (xx) |
| HU (1) | HUP0100336A3 (xx) |
| ID (1) | ID26665A (xx) |
| IL (1) | IL137329A0 (xx) |
| NO (1) | NO20003694L (xx) |
| WO (1) | WO1999037605A1 (xx) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0201213A3 (en) | 1999-01-22 | 2003-02-28 | Wyeth Corp | Pirimidinyl, pirazinyl and thiadiazolyl phenylalanin derivatives which treat vla-4 related disorders and pharaceutical compositions containing them |
| WO2000043372A1 (en) * | 1999-01-22 | 2000-07-27 | Elan Pharmaceuticals, Inc. | Acyl derivatives which treat vla-4 related disorders |
| US6436904B1 (en) | 1999-01-25 | 2002-08-20 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| EP1161416B1 (en) | 1999-03-01 | 2004-04-14 | Elan Pharmaceuticals, Inc. | Alpha-aminoacetic acid derivatives useful as alpha 4 beta 7 - receptor antagonists |
| WO2001042192A2 (en) * | 1999-12-07 | 2001-06-14 | Novartis Ag | Vla-4 integrin antagonists |
| JP2003519697A (ja) | 1999-12-28 | 2003-06-24 | ファイザー・プロダクツ・インク | 炎症性疾患、自己免疫疾患および呼吸器疾患の処置に有用な非ペプチド系のｖｌａ−４依存性細胞結合阻害薬 |
| DE10019755A1 (de) * | 2000-04-20 | 2001-11-08 | Bayer Ag | Neue Aminoaryl/cycloalkylcarbonsäuren als Integrinantagonisten |
| GB2369357A (en) * | 2000-10-09 | 2002-05-29 | Bayer Ag | Aliphatic, cyclic amino carboxylic acids as integrin antagonists |
| GB2367816A (en) | 2000-10-09 | 2002-04-17 | Bayer Ag | Urea- and thiourea-containing derivatives of beta-amino acids |
| GB2377933A (en) | 2001-07-06 | 2003-01-29 | Bayer Ag | Succinic acid derivatives useful as integrin antagonists |
| TWI281470B (en) | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
| TW200307671A (en) | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
| TW200610754A (en) * | 2004-06-14 | 2006-04-01 | Daiichi Seiyaku Co | Vla-4 inhibitor |
| GB0523576D0 (en) * | 2005-11-18 | 2005-12-28 | Theradeas Ltd | Drug composition and its use in therapy |
| EP2124996A4 (en) | 2007-02-20 | 2010-03-24 | Merrimack Pharmaceuticals Inc | METHODS OF TREATING MULTIPLE SCLEROSIS BY ADMINISTERING ALPHA-FETOPROTEIN COMBINED WITH INTEGRIN ANTAGONIST |
| CA2721093A1 (en) | 2008-04-11 | 2009-10-15 | Merrimack Pharmaceuticals, Inc. | Human serum albumin linkers and conjugates thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6306840B1 (en) * | 1995-01-23 | 2001-10-23 | Biogen, Inc. | Cell adhesion inhibitors |
| EP1042279B1 (en) * | 1997-12-23 | 2005-03-02 | Aventis Pharma Limited | Substituted beta-alanines |
-
1999
- 1999-01-21 EE EEP200000428A patent/EE200000428A/xx unknown
- 1999-01-21 CA CA002318639A patent/CA2318639A1/en not_active Abandoned
- 1999-01-21 BR BR9907733-7A patent/BR9907733A/pt not_active IP Right Cessation
- 1999-01-21 ID IDW20001404A patent/ID26665A/id unknown
- 1999-01-21 AU AU28292/99A patent/AU746174B2/en not_active Ceased
- 1999-01-21 CN CN99803780A patent/CN1294576A/zh active Pending
- 1999-01-21 JP JP2000528529A patent/JP4564654B2/ja not_active Expired - Fee Related
- 1999-01-21 WO PCT/EP1999/000384 patent/WO1999037605A1/en not_active Application Discontinuation
- 1999-01-21 IL IL13732999A patent/IL137329A0/xx unknown
- 1999-01-21 HU HU0100336A patent/HUP0100336A3/hu unknown
- 1999-01-21 EP EP99908811A patent/EP1049665A1/en not_active Withdrawn
- 1999-01-21 KR KR1020007008039A patent/KR20010034317A/ko not_active Application Discontinuation
-
2000
- 2000-07-19 NO NO20003694A patent/NO20003694L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999037605A1 (en) | 1999-07-29 |
| JP2002501039A (ja) | 2002-01-15 |
| NO20003694L (no) | 2000-09-20 |
| EE200000428A (et) | 2001-12-17 |
| HUP0100336A3 (en) | 2002-11-28 |
| NO20003694D0 (no) | 2000-07-19 |
| ID26665A (id) | 2001-01-25 |
| HUP0100336A2 (hu) | 2001-07-30 |
| AU746174B2 (en) | 2002-04-18 |
| JP4564654B2 (ja) | 2010-10-20 |
| AU2829299A (en) | 1999-08-09 |
| EP1049665A1 (en) | 2000-11-08 |
| BR9907733A (pt) | 2000-10-17 |
| CN1294576A (zh) | 2001-05-09 |
| KR20010034317A (ko) | 2001-04-25 |
| CA2318639A1 (en) | 1999-07-29 |
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