ID26665A - VLA-4 ANTAGONISTS - Google Patents
VLA-4 ANTAGONISTSInfo
- Publication number
- ID26665A ID26665A IDW20001404A ID20001404A ID26665A ID 26665 A ID26665 A ID 26665A ID W20001404 A IDW20001404 A ID W20001404A ID 20001404 A ID20001404 A ID 20001404A ID 26665 A ID26665 A ID 26665A
- Authority
- ID
- Indonesia
- Prior art keywords
- vla
- antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1233698A | 1998-01-23 | 1998-01-23 | |
| US11072398P | 1998-12-03 | 1998-12-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID26665A true ID26665A (en) | 2001-01-25 |
Family
ID=26683440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW20001404A ID26665A (en) | 1998-01-23 | 1999-01-21 | VLA-4 ANTAGONISTS |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1049665A1 (en) |
| JP (1) | JP4564654B2 (en) |
| KR (1) | KR20010034317A (en) |
| CN (1) | CN1294576A (en) |
| AU (1) | AU746174B2 (en) |
| BR (1) | BR9907733A (en) |
| CA (1) | CA2318639A1 (en) |
| EE (1) | EE200000428A (en) |
| HU (1) | HUP0100336A3 (en) |
| ID (1) | ID26665A (en) |
| IL (1) | IL137329A0 (en) |
| NO (1) | NO20003694L (en) |
| WO (1) | WO1999037605A1 (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60036918D1 (en) | 1999-01-22 | 2007-12-13 | Elan Pharm Inc | COMPOUNDS INHIBITING THE VLA-4-MEDIATED ADHESION OF LEUKOCYTES |
| WO2000043372A1 (en) * | 1999-01-22 | 2000-07-27 | Elan Pharmaceuticals, Inc. | Acyl derivatives which treat vla-4 related disorders |
| US6436904B1 (en) | 1999-01-25 | 2002-08-20 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| WO2000051974A1 (en) | 1999-03-01 | 2000-09-08 | Elan Pharmaceuticals, Inc. | Alpha-aminoacetic acid derivatives useful as alpha 4 beta 7 - receptor antagonists |
| JP2003516380A (en) * | 1999-12-07 | 2003-05-13 | ノバルティス アクチエンゲゼルシャフト | VLA-4 integrin antagonist |
| PL357109A1 (en) | 1999-12-28 | 2004-07-12 | Pfizer Products Inc. | Non-peptidyl inhibitors of vla-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases |
| DE10019755A1 (en) * | 2000-04-20 | 2001-11-08 | Bayer Ag | New cyclic carboxylic acids are integrin antagonists, useful for treating inflammatory diseases, autoimmune and immune disorders, e.g. atherosclerosis, asthma and diabetes |
| GB2367816A (en) * | 2000-10-09 | 2002-04-17 | Bayer Ag | Urea- and thiourea-containing derivatives of beta-amino acids |
| GB2369357A (en) * | 2000-10-09 | 2002-05-29 | Bayer Ag | Aliphatic, cyclic amino carboxylic acids as integrin antagonists |
| GB2377933A (en) | 2001-07-06 | 2003-01-29 | Bayer Ag | Succinic acid derivatives useful as integrin antagonists |
| TWI281470B (en) | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
| TW200307671A (en) | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
| TW200610754A (en) * | 2004-06-14 | 2006-04-01 | Daiichi Seiyaku Co | Vla-4 inhibitor |
| GB0523576D0 (en) * | 2005-11-18 | 2005-12-28 | Theradeas Ltd | Drug composition and its use in therapy |
| WO2008103378A2 (en) | 2007-02-20 | 2008-08-28 | Merrimack Pharmaceuticals, Inc. | Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist |
| PL2288715T3 (en) | 2008-04-11 | 2015-03-31 | Merrimack Pharmaceuticals Inc | Human serum albumin linkers and conjugates thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6306840B1 (en) * | 1995-01-23 | 2001-10-23 | Biogen, Inc. | Cell adhesion inhibitors |
| IL136584A (en) * | 1997-12-23 | 2005-03-20 | Aventis Pharma Ltd | SUBSTITUTED beta-ALANINES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND USES THEREOF |
-
1999
- 1999-01-21 EP EP99908811A patent/EP1049665A1/en not_active Withdrawn
- 1999-01-21 HU HU0100336A patent/HUP0100336A3/en unknown
- 1999-01-21 WO PCT/EP1999/000384 patent/WO1999037605A1/en not_active Application Discontinuation
- 1999-01-21 KR KR1020007008039A patent/KR20010034317A/en not_active Application Discontinuation
- 1999-01-21 JP JP2000528529A patent/JP4564654B2/en not_active Expired - Fee Related
- 1999-01-21 BR BR9907733-7A patent/BR9907733A/en not_active IP Right Cessation
- 1999-01-21 CA CA002318639A patent/CA2318639A1/en not_active Abandoned
- 1999-01-21 CN CN99803780A patent/CN1294576A/en active Pending
- 1999-01-21 EE EEP200000428A patent/EE200000428A/en unknown
- 1999-01-21 IL IL13732999A patent/IL137329A0/en unknown
- 1999-01-21 AU AU28292/99A patent/AU746174B2/en not_active Ceased
- 1999-01-21 ID IDW20001404A patent/ID26665A/en unknown
-
2000
- 2000-07-19 NO NO20003694A patent/NO20003694L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EE200000428A (en) | 2001-12-17 |
| NO20003694L (en) | 2000-09-20 |
| NO20003694D0 (en) | 2000-07-19 |
| EP1049665A1 (en) | 2000-11-08 |
| CN1294576A (en) | 2001-05-09 |
| JP4564654B2 (en) | 2010-10-20 |
| JP2002501039A (en) | 2002-01-15 |
| IL137329A0 (en) | 2001-07-24 |
| WO1999037605A1 (en) | 1999-07-29 |
| HUP0100336A2 (en) | 2001-07-30 |
| BR9907733A (en) | 2000-10-17 |
| KR20010034317A (en) | 2001-04-25 |
| CA2318639A1 (en) | 1999-07-29 |
| HUP0100336A3 (en) | 2002-11-28 |
| AU746174B2 (en) | 2002-04-18 |
| AU2829299A (en) | 1999-08-09 |
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