ID22902A - Bahan penyerap untuk menghilangkan virus hepatitis c, alat peneyerap, dan metode penyerapan - Google Patents
Bahan penyerap untuk menghilangkan virus hepatitis c, alat peneyerap, dan metode penyerapanInfo
- Publication number
- ID22902A ID22902A IDW991180A ID991180A ID22902A ID 22902 A ID22902 A ID 22902A ID W991180 A IDW991180 A ID W991180A ID 991180 A ID991180 A ID 991180A ID 22902 A ID22902 A ID 22902A
- Authority
- ID
- Indonesia
- Prior art keywords
- virus
- hcv
- adsorbent
- absorption
- hepatitis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
- B01J20/26—Synthetic macromolecular compounds
- B01J20/262—Synthetic macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by polycondensation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
- B01J20/26—Synthetic macromolecular compounds
- B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
- B01J20/28078—Pore diameter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
- B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
- B01J20/3255—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising a cyclic structure containing at least one of the heteroatoms nitrogen, oxygen or sulfur, e.g. heterocyclic or heteroaromatic structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
- B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7509—General characteristics of the apparatus with filters for virus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
- B01J2220/58—Use in a single column
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- External Artificial Organs (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7148397 | 1997-03-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID22902A true ID22902A (id) | 1999-12-16 |
Family
ID=13461947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW991180A ID22902A (id) | 1997-03-25 | 1998-03-25 | Bahan penyerap untuk menghilangkan virus hepatitis c, alat peneyerap, dan metode penyerapan |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6600014B2 (id) |
| EP (1) | EP0972530A4 (id) |
| KR (2) | KR20060015703A (id) |
| CN (1) | CN1286535C (id) |
| CA (1) | CA2284619A1 (id) |
| ID (1) | ID22902A (id) |
| TW (1) | TW514537B (id) |
| WO (1) | WO1998042392A1 (id) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1420641A4 (en) * | 2001-08-01 | 2005-05-25 | Anil K Chauhan | IMMUNE COMPLEX |
| JP4685294B2 (ja) * | 2001-09-18 | 2011-05-18 | 株式会社カネカ | 新規ペプチド、生産方法、新規吸着体、吸着器および吸着方法 |
| CA2464351A1 (en) * | 2001-10-16 | 2003-04-24 | Asahi Medical Co., Ltd. | Method for selectively removing virus and leukocytes, removing material and removing apparatus |
| JP2003235959A (ja) * | 2002-02-14 | 2003-08-26 | Nippon Koutai Kenkyusho:Kk | C型肝炎ウイルスの除去・減量方法 |
| CA2559719A1 (en) * | 2004-03-17 | 2005-09-29 | University Of Hawaii | Sensor constructs and detection methods |
| US20050239198A1 (en) * | 2004-04-27 | 2005-10-27 | Baxter International, Inc. | Stirred-tank reactor system |
| CN1988926B (zh) * | 2004-07-23 | 2010-05-05 | 株式会社钟化 | 填充有除去了水不溶性微粒的吸附材料的直接血液灌注用吸附器、与除去了水不溶性微粒的直接血液灌注用吸附材料的取得方法 |
| RU2432187C2 (ru) | 2005-12-13 | 2011-10-27 | ЭксТера Медикал ЛЛС | Метод экстракорпорального удаления из крови патогенных микробов, клеток воспаления или белков воспаления |
| CN101069751B (zh) * | 2006-05-10 | 2011-02-09 | 广州康盛生物科技有限公司 | 一种蛋白a免疫吸附材料及其制备方法 |
| KR100931027B1 (ko) * | 2006-06-27 | 2009-12-10 | 한국생명공학연구원 | N-말단에 시스테인 태그된 단백질 g 변형체 |
| CN101185878B (zh) * | 2006-11-17 | 2010-05-26 | 广州康盛生物科技有限公司 | 一种用于去除致病抗体及其复合物的蛋白a免疫吸附材料及其合成方法和应用 |
| US7875182B2 (en) | 2006-11-20 | 2011-01-25 | Cytosorbents, Inc. | Size-selective hemoperfusion polymeric adsorbents |
| US9604196B2 (en) | 2006-11-20 | 2017-03-28 | Cytosorbent, Inc. | Size-selective hemocompatible polymer system |
| US8211310B2 (en) | 2006-11-20 | 2012-07-03 | Cytosorbents, Inc. | Size-selective polymer system |
| WO2008155683A1 (en) | 2007-06-18 | 2008-12-24 | Firmenich Sa | Malodor counteracting compositions and method for their use |
| PH12012500702A1 (en) * | 2009-10-08 | 2012-10-29 | Otsuka Pharma Co Ltd | An immunoactivation blood perfusion filter for the treatment of malignant tumors |
| CN102740859B (zh) * | 2009-12-01 | 2016-08-10 | 艾克塞拉医疗公司 | 使用固定于表面的多糖从血液中去除细胞因子的方法 |
| WO2012112724A1 (en) | 2011-02-15 | 2012-08-23 | Exthera Medical, Llc | Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines |
| US20120219633A1 (en) * | 2011-02-28 | 2012-08-30 | Pall Corporation | Removal of immunoglobulins and leukocytes from biological fluids |
| EP2861273B1 (en) | 2012-06-13 | 2017-08-23 | ExThera Medical Corporation | Use of heparin and carbohydrates to treat cancer |
| EP3013445B1 (en) | 2013-06-24 | 2019-11-06 | ExThera Medical Corporation | Blood filtration system containing mannose coated substrate |
| CN103394331B (zh) * | 2013-07-25 | 2015-02-11 | 武汉大学 | 一种丙型肝炎病毒吸附剂及其制备方法与应用 |
| JP6806563B2 (ja) | 2013-11-08 | 2021-01-06 | エクステラ・メディカル・コーポレーション | 吸着媒体を使用する感染症の診断法 |
| CN103933947B (zh) * | 2014-04-10 | 2015-10-14 | 大连理工大学 | 用于清除类风湿因子的血液净化材料及其制备方法 |
| MX2016013873A (es) | 2014-04-24 | 2017-03-09 | Exthera Medical Corp | Metodo para eliminar bacterias de la sangre usando alta velocidad de flujo. |
| MX2017003723A (es) | 2014-09-22 | 2017-06-30 | Exthera Medical Corp | Dispositivo de hemoperfusion portatil. |
| JP2016164977A (ja) * | 2015-02-27 | 2016-09-08 | キヤノン株式会社 | ナノインプリント用液体材料、ナノインプリント用液体材料の製造方法、硬化物パターンの製造方法、光学部品の製造方法、回路基板の製造方法、および電子部品の製造方法 |
| CN104801278A (zh) * | 2015-03-29 | 2015-07-29 | 武汉瑞法医疗器械有限公司 | 艾滋病毒亲和吸附剂的制备方法 |
| WO2017151797A1 (en) | 2016-03-02 | 2017-09-08 | Exthera Medical Corporation | Method for treating drug intoxication |
| US11911551B2 (en) | 2016-03-02 | 2024-02-27 | Exthera Medical Corporation | Method for treating drug intoxication |
| KR20220009400A (ko) | 2019-05-16 | 2022-01-24 | 엑스테라 메디컬 코퍼레이션 | 내피 글리코칼릭스 구조의 조절 방법 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1221307A (en) * | 1982-12-02 | 1987-05-05 | Nobutaka Tani | Adsorbent and process for preparing the same |
| JPS59193135A (ja) | 1983-04-18 | 1984-11-01 | Kanegafuchi Chem Ind Co Ltd | 吸着体 |
| US4681870A (en) * | 1985-01-11 | 1987-07-21 | Imre Corporation | Protein A-silica immunoadsorbent and process for its production |
| US5037649A (en) * | 1985-01-11 | 1991-08-06 | Imre Corporation | Method for treatment of HIV-infected patients |
| GB8902770D0 (en) * | 1989-02-08 | 1989-03-30 | Bioprocessing Ltd | Improvements in or relating to supports for immunoaffinity separations |
| EP0447984A1 (en) * | 1990-03-20 | 1991-09-25 | Abbott Laboratories | Hyperimmune globulin against hepatitis C virus and method for making same |
| JPH0640926A (ja) * | 1992-07-24 | 1994-02-15 | Chemo Sero Therapeut Res Inst | C型肝炎ウイルスの除去方法 |
| RU2095815C1 (ru) * | 1994-12-22 | 1997-11-10 | Леонид Николаевич Падюков | Способ получения иммуносорбента для диагностики вирусного гепатита с |
| DK0752425T3 (da) * | 1995-06-21 | 2000-04-10 | Tecnogen Scpa | Peptidligander for den konstante region på immunoglobuliner |
| JPH093350A (ja) * | 1995-06-22 | 1997-01-07 | Daisutaa Japan Kk | 青色系分散染料混合物 |
| DE69627333T2 (de) * | 1995-06-26 | 2004-02-12 | PerSeptive Biosystems, Inc., Framingham | Automatisierte, kontinuierliche mehrdimensionale hochgeschwindigkeitsmolekularselektion und -analyse |
| JPH0933530A (ja) * | 1995-07-19 | 1997-02-07 | B M L:Kk | ウイルスの定量方法 |
| JP3908278B2 (ja) * | 1996-01-25 | 2007-04-25 | 株式会社カネカ | 免疫グロブリンおよびその複合体の吸着材、吸着方法、および吸着装置 |
| US5846735A (en) * | 1996-04-18 | 1998-12-08 | University Of Iowa Research Foundation | Hepatitis C virus Fc-binding function |
-
1998
- 1998-03-25 TW TW087104518A patent/TW514537B/zh not_active IP Right Cessation
- 1998-03-25 WO PCT/JP1998/001317 patent/WO1998042392A1/ja not_active Ceased
- 1998-03-25 CN CNB988036614A patent/CN1286535C/zh not_active Expired - Fee Related
- 1998-03-25 KR KR1020067002145A patent/KR20060015703A/ko not_active Ceased
- 1998-03-25 ID IDW991180A patent/ID22902A/id unknown
- 1998-03-25 US US09/380,644 patent/US6600014B2/en not_active Expired - Fee Related
- 1998-03-25 CA CA002284619A patent/CA2284619A1/en not_active Abandoned
- 1998-03-25 EP EP98910991A patent/EP0972530A4/en not_active Withdrawn
- 1998-03-25 KR KR1019997008754A patent/KR20010005686A/ko not_active Ceased
-
2003
- 2003-06-11 US US10/458,297 patent/US7056507B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7056507B2 (en) | 2006-06-06 |
| CN1251048A (zh) | 2000-04-19 |
| US20030044769A1 (en) | 2003-03-06 |
| EP0972530A4 (en) | 2003-01-29 |
| US6600014B2 (en) | 2003-07-29 |
| US20040006214A1 (en) | 2004-01-08 |
| EP0972530A1 (en) | 2000-01-19 |
| KR20060015703A (ko) | 2006-02-17 |
| TW514537B (en) | 2002-12-21 |
| KR20010005686A (ko) | 2001-01-15 |
| WO1998042392A1 (en) | 1998-10-01 |
| CN1286535C (zh) | 2006-11-29 |
| CA2284619A1 (en) | 1998-10-01 |
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