ID15967A - Agen terapi diabetes - Google Patents

Agen terapi diabetes

Info

Publication number
ID15967A
ID15967A IDP970474A ID970474A ID15967A ID 15967 A ID15967 A ID 15967A ID P970474 A IDP970474 A ID P970474A ID 970474 A ID970474 A ID 970474A ID 15967 A ID15967 A ID 15967A
Authority
ID
Indonesia
Prior art keywords
therapy agents
diabetes therapy
diabetes
agents
therapy
Prior art date
Application number
IDP970474A
Other languages
English (en)
Inventor
Hisaishi Shinkai
Hidekazu Ozeki
Noboru Furukawa
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of ID15967A publication Critical patent/ID15967A/id

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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C07C233/31—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
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    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
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    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
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    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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FR2849598B1 (fr) 2003-01-07 2006-09-22 Merck Sante Sas Utilisation d'inhibiteurs de la kynurenine-3-hydroxylase pour le traitement du diabete, par augmentation du nombre de cellules des ilots de langerhans
FR2880885B1 (fr) * 2005-01-14 2009-01-30 Merck Sante Soc Par Actions Si Derives d'acide phenylbenzoique, procedes pour leur preparation, compositions pharmaceutiques les contenant et applications en therapeutique
DE102006031813B4 (de) 2006-07-07 2011-04-28 Christian-Albrechts-Universität Zu Kiel Verwendung basischer Acetophenone als Hemmstoffe von NO-Synthasen
SG185318A1 (en) * 2007-01-12 2012-11-29 Novartis Ag Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid
CN101677930A (zh) 2007-05-23 2010-03-24 吉万奥丹股份有限公司 用作清凉剂的丁酮衍生物
CN102344369A (zh) * 2010-07-30 2012-02-08 华东师范大学 侧链含芴单元的高取向发光聚乙炔单体及其制备方法
LT2605652T (lt) 2010-08-18 2018-03-12 Samumed, Llc Diketonai ir hidroksiketonai kaip katenino signalinio kelio aktyvintojai
JP5705984B2 (ja) 2010-08-23 2015-04-22 ノバルティス アーゲー Ｎｅｐ阻害剤を製造するための中間体の調製方法
BR112015010577A2 (pt) 2012-11-09 2017-07-11 Glaxosmithkline Llc compostos utilizados como inibidores da diacilglicerol aciltransferase
PE20151721A1 (es) 2013-02-22 2015-12-07 Samumed Llc Y-dicetonas como activadores de la ruta de senalizacion de wnt/b-catenina
RS59797B1 (sr) 2014-08-20 2020-02-28 Samumed Llc Gama-diketoni za tretman i prevenciju starenja kože i bora
CN109420175A (zh) * 2017-09-01 2019-03-05 任洁 基于cox的血糖调节机制
CN109419791A (zh) * 2017-09-04 2019-03-05 任洁 芬布芬作为糖尿病相关靶点调节剂的新用途
CN109422644A (zh) * 2017-09-04 2019-03-05 任洁 芬布芬体内代谢产物及衍生物的用途
CN109422645A (zh) * 2017-09-04 2019-03-05 任洁 芬布芬体内代谢产物及衍生物作为糖尿病相关靶点调节剂的用途
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NO983770D0 (no) 1998-08-18
CA2246725A1 (en) 1997-08-21
IL125820A0 (en) 1999-04-11
EP0885869A1 (en) 1998-12-23
HUP9900715A3 (en) 2000-11-28
KR19990082639A (ko) 1999-11-25
AU719396B2 (en) 2000-05-11
AU1673297A (en) 1997-09-02
NZ331801A (en) 2001-01-26
WO1997030017A1 (fr) 1997-08-21
BR9707588A (pt) 1999-07-27
BG102759A (en) 1999-09-30
PL328519A1 (en) 1999-02-01
NO983770L (no) 1998-10-19
CZ256198A3 (cs) 1998-12-16
HUP9900715A2 (hu) 1999-06-28
CN1216522A (zh) 1999-05-12

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