HUT67836A - Pyridazinone acetic acids having aldose reductase inhibitory activity, pharmaceutical compositions containing them and process for preparation of them - Google Patents

Pyridazinone acetic acids having aldose reductase inhibitory activity, pharmaceutical compositions containing them and process for preparation of them Download PDF

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Publication number
HUT67836A
HUT67836A HU9302728A HU9302728A HUT67836A HU T67836 A HUT67836 A HU T67836A HU 9302728 A HU9302728 A HU 9302728A HU 9302728 A HU9302728 A HU 9302728A HU T67836 A HUT67836 A HU T67836A
Authority
HU
Hungary
Prior art keywords
methyl
formula
oxo
dihydro
acetic acid
Prior art date
Application number
HU9302728A
Other languages
English (en)
Hungarian (hu)
Other versions
HU9302728D0 (en
Inventor
Banavara L Mylari
William J Zembrowski
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HU9302728D0 publication Critical patent/HU9302728D0/hu
Publication of HUT67836A publication Critical patent/HUT67836A/hu

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • C07D237/32Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU9302728A 1991-03-28 1992-03-09 Pyridazinone acetic acids having aldose reductase inhibitory activity, pharmaceutical compositions containing them and process for preparation of them HUT67836A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67691991A 1991-03-28 1991-03-28

Publications (2)

Publication Number Publication Date
HU9302728D0 HU9302728D0 (en) 1993-12-28
HUT67836A true HUT67836A (en) 1995-05-29

Family

ID=24716565

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9302728A HUT67836A (en) 1991-03-28 1992-03-09 Pyridazinone acetic acids having aldose reductase inhibitory activity, pharmaceutical compositions containing them and process for preparation of them

Country Status (19)

Country Link
EP (1) EP0582643A1 (enExample)
JP (1) JPH06500793A (enExample)
CN (1) CN1065269A (enExample)
AU (1) AU658887B2 (enExample)
BR (1) BR9205810A (enExample)
CA (1) CA2107104A1 (enExample)
CZ (1) CZ387092A3 (enExample)
DE (1) DE9290035U1 (enExample)
FI (1) FI934222A0 (enExample)
HU (1) HUT67836A (enExample)
IE (1) IE920979A1 (enExample)
IL (1) IL101325A0 (enExample)
MX (1) MX9201414A (enExample)
NZ (1) NZ242152A (enExample)
PT (1) PT100301A (enExample)
TW (1) TW207998B (enExample)
WO (1) WO1992017446A2 (enExample)
YU (1) YU30392A (enExample)
ZA (1) ZA922238B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2240657T3 (es) 2001-02-28 2005-10-16 Pfizer Products Inc. Compuestos de sulfonilpiridazinona utiles como inhibidores de aldosa reductasa.
SE0100873D0 (sv) * 2001-03-13 2001-03-13 Astrazeneca Ab Method of treatment
ATE352551T1 (de) 2001-03-30 2007-02-15 Pfizer Prod Inc Pyridazinon aldose reductase inhibitoren
AU761191B2 (en) * 2001-05-24 2003-05-29 Pfizer Products Inc. Therapies for tissue damage resulting from ischemia
US7572910B2 (en) 2003-02-20 2009-08-11 Pfizer, Inc. Pyridazinone aldose reductase inhibitors
CN111617072B (zh) * 2019-02-27 2023-06-20 苏州凯祥生物科技有限公司 一种高尿酸血症药物组合物及用于治疗高尿酸血症的药物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0676391B2 (ja) * 1987-06-09 1994-09-28 フアイザー・インコーポレイテツド ベンゾチアゾール等の複素環側鎖を有するオキソフタラジニル酢酸類の製造方法
FR2647676A1 (fr) * 1989-06-05 1990-12-07 Union Pharma Scient Appl Nouveaux derives de pyridazinone, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase

Also Published As

Publication number Publication date
IE920979A1 (en) 1992-10-07
BR9205810A (pt) 1994-06-28
TW207998B (enExample) 1993-06-21
WO1992017446A3 (en) 1992-11-26
MX9201414A (es) 1992-10-01
YU30392A (sh) 1994-11-15
PT100301A (pt) 1993-06-30
CN1065269A (zh) 1992-10-14
FI934222L (fi) 1993-09-27
CZ387092A3 (en) 1994-02-16
NZ242152A (en) 1994-07-26
CA2107104A1 (en) 1992-09-29
FI934222A7 (fi) 1993-09-27
WO1992017446A2 (en) 1992-10-15
ZA922238B (en) 1993-09-27
AU658887B2 (en) 1995-05-04
EP0582643A1 (en) 1994-02-16
AU1779692A (en) 1992-11-02
DE9290035U1 (de) 1993-11-18
IL101325A0 (en) 1992-11-15
FI934222A0 (fi) 1993-09-27
HU9302728D0 (en) 1993-12-28
JPH06500793A (ja) 1994-01-27

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DFD9 Temporary protection cancelled due to non-payment of fee