CN1065269A - 哒嗪酮乙酸衍生物 - Google Patents
哒嗪酮乙酸衍生物 Download PDFInfo
- Publication number
- CN1065269A CN1065269A CN92102224A CN92102224A CN1065269A CN 1065269 A CN1065269 A CN 1065269A CN 92102224 A CN92102224 A CN 92102224A CN 92102224 A CN92102224 A CN 92102224A CN 1065269 A CN1065269 A CN 1065269A
- Authority
- CN
- China
- Prior art keywords
- base
- methyl
- formula
- oxo
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67691991A | 1991-03-28 | 1991-03-28 | |
| US676,919 | 1991-03-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1065269A true CN1065269A (zh) | 1992-10-14 |
Family
ID=24716565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN92102224A Pending CN1065269A (zh) | 1991-03-28 | 1992-03-27 | 哒嗪酮乙酸衍生物 |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0582643A1 (enExample) |
| JP (1) | JPH06500793A (enExample) |
| CN (1) | CN1065269A (enExample) |
| AU (1) | AU658887B2 (enExample) |
| BR (1) | BR9205810A (enExample) |
| CA (1) | CA2107104A1 (enExample) |
| CZ (1) | CZ387092A3 (enExample) |
| DE (1) | DE9290035U1 (enExample) |
| FI (1) | FI934222A7 (enExample) |
| HU (1) | HUT67836A (enExample) |
| IE (1) | IE920979A1 (enExample) |
| IL (1) | IL101325A0 (enExample) |
| MX (1) | MX9201414A (enExample) |
| NZ (1) | NZ242152A (enExample) |
| PT (1) | PT100301A (enExample) |
| TW (1) | TW207998B (enExample) |
| WO (1) | WO1992017446A2 (enExample) |
| YU (1) | YU30392A (enExample) |
| ZA (1) | ZA922238B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2240657T3 (es) | 2001-02-28 | 2005-10-16 | Pfizer Products Inc. | Compuestos de sulfonilpiridazinona utiles como inhibidores de aldosa reductasa. |
| SE0100873D0 (sv) * | 2001-03-13 | 2001-03-13 | Astrazeneca Ab | Method of treatment |
| YU71403A (sh) | 2001-03-30 | 2006-05-25 | Pfizer Products Inc. | Piridazinoni kao inhibitori aldoza reduktaze |
| AU761191B2 (en) * | 2001-05-24 | 2003-05-29 | Pfizer Products Inc. | Therapies for tissue damage resulting from ischemia |
| US7572910B2 (en) | 2003-02-20 | 2009-08-11 | Pfizer, Inc. | Pyridazinone aldose reductase inhibitors |
| CN111617072B (zh) * | 2019-02-27 | 2023-06-20 | 苏州凯祥生物科技有限公司 | 一种高尿酸血症药物组合物及用于治疗高尿酸血症的药物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0676391B2 (ja) * | 1987-06-09 | 1994-09-28 | フアイザー・インコーポレイテツド | ベンゾチアゾール等の複素環側鎖を有するオキソフタラジニル酢酸類の製造方法 |
| FR2647676A1 (fr) * | 1989-06-05 | 1990-12-07 | Union Pharma Scient Appl | Nouveaux derives de pyridazinone, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase |
-
1992
- 1992-03-09 CZ CS923870A patent/CZ387092A3/cs unknown
- 1992-03-09 CA CA002107104A patent/CA2107104A1/en not_active Abandoned
- 1992-03-09 EP EP92910955A patent/EP0582643A1/en not_active Withdrawn
- 1992-03-09 HU HU9302728A patent/HUT67836A/hu unknown
- 1992-03-09 BR BR9205810A patent/BR9205810A/pt not_active Application Discontinuation
- 1992-03-09 JP JP4509938A patent/JPH06500793A/ja active Pending
- 1992-03-09 AU AU17796/92A patent/AU658887B2/en not_active Ceased
- 1992-03-09 FI FI934222A patent/FI934222A7/fi not_active Application Discontinuation
- 1992-03-09 DE DE9290035U patent/DE9290035U1/de not_active Expired - Lifetime
- 1992-03-09 WO PCT/US1992/001603 patent/WO1992017446A2/en not_active Ceased
- 1992-03-13 TW TW081101914A patent/TW207998B/zh active
- 1992-03-22 IL IL101325A patent/IL101325A0/xx unknown
- 1992-03-26 YU YU30392A patent/YU30392A/sh unknown
- 1992-03-26 PT PT100301A patent/PT100301A/pt not_active Application Discontinuation
- 1992-03-27 ZA ZA922238A patent/ZA922238B/xx unknown
- 1992-03-27 NZ NZ24215292A patent/NZ242152A/en unknown
- 1992-03-27 IE IE097992A patent/IE920979A1/en not_active Application Discontinuation
- 1992-03-27 MX MX9201414A patent/MX9201414A/es unknown
- 1992-03-27 CN CN92102224A patent/CN1065269A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU1779692A (en) | 1992-11-02 |
| TW207998B (enExample) | 1993-06-21 |
| DE9290035U1 (de) | 1993-11-18 |
| HUT67836A (en) | 1995-05-29 |
| BR9205810A (pt) | 1994-06-28 |
| YU30392A (sh) | 1994-11-15 |
| JPH06500793A (ja) | 1994-01-27 |
| EP0582643A1 (en) | 1994-02-16 |
| CZ387092A3 (en) | 1994-02-16 |
| HU9302728D0 (en) | 1993-12-28 |
| FI934222L (fi) | 1993-09-27 |
| PT100301A (pt) | 1993-06-30 |
| NZ242152A (en) | 1994-07-26 |
| MX9201414A (es) | 1992-10-01 |
| ZA922238B (en) | 1993-09-27 |
| AU658887B2 (en) | 1995-05-04 |
| FI934222A0 (fi) | 1993-09-27 |
| IL101325A0 (en) | 1992-11-15 |
| FI934222A7 (fi) | 1993-09-27 |
| WO1992017446A2 (en) | 1992-10-15 |
| WO1992017446A3 (en) | 1992-11-26 |
| IE920979A1 (en) | 1992-10-07 |
| CA2107104A1 (en) | 1992-09-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| AD01 | Patent right deemed abandoned | ||
| C20 | Patent right or utility model deemed to be abandoned or is abandoned |