HUT67788A - 2,4-dioxo-thiazolidine derivatives, their preparation and pharmaceutical compositions containing them - Google Patents

2,4-dioxo-thiazolidine derivatives, their preparation and pharmaceutical compositions containing them

Info

Publication number
HUT67788A
HUT67788A HU9204130A HU9204130A HUT67788A HU T67788 A HUT67788 A HU T67788A HU 9204130 A HU9204130 A HU 9204130A HU 9204130 A HU9204130 A HU 9204130A HU T67788 A HUT67788 A HU T67788A
Authority
HU
Hungary
Prior art keywords
alkyl
hydrogen
dioxo
preparation
pharmaceutical compositions
Prior art date
Application number
HU9204130A
Other languages
English (en)
Other versions
HU9204130D0 (en
HU215450B (hu
Inventor
Takahide Nishi
Hiroyoshi Horikoshi
Takashi Fujita
Tsutomu Kanai
Yuichi Aizawa
Kunio Wada
Takao Yoshioka
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of HU9204130D0 publication Critical patent/HU9204130D0/hu
Publication of HUT67788A publication Critical patent/HUT67788A/hu
Publication of HU215450B publication Critical patent/HU215450B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
HUP9204130A 1991-12-26 1992-12-23 Eljárás 2,4-dioxo-tiazolidin-származékok előállítására HU215450B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34457191 1991-12-26

Publications (3)

Publication Number Publication Date
HU9204130D0 HU9204130D0 (en) 1993-04-28
HUT67788A true HUT67788A (en) 1995-04-28
HU215450B HU215450B (hu) 1999-04-28

Family

ID=18370304

Family Applications (1)

Application Number Title Priority Date Filing Date
HUP9204130A HU215450B (hu) 1991-12-26 1992-12-23 Eljárás 2,4-dioxo-tiazolidin-származékok előállítására

Country Status (21)

Country Link
EP (1) EP0549365B1 (hu)
JP (1) JP2833949B2 (hu)
CN (1) CN1032751C (hu)
AT (1) ATE126221T1 (hu)
AU (1) AU654223B2 (hu)
CA (1) CA2086277A1 (hu)
CZ (1) CZ389792A3 (hu)
DE (1) DE69204041T2 (hu)
DK (1) DK0549365T3 (hu)
ES (1) ES2078671T3 (hu)
FI (1) FI925849A (hu)
GR (1) GR3017632T3 (hu)
HK (1) HK196095A (hu)
HU (1) HU215450B (hu)
IL (1) IL104238A (hu)
MX (1) MX9207595A (hu)
NO (1) NO302471B1 (hu)
NZ (1) NZ245612A (hu)
RU (1) RU2095354C1 (hu)
TW (1) TW211007B (hu)
ZA (1) ZA9210021B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
EP0783888A1 (en) * 1995-12-26 1997-07-16 Sankyo Company Limited Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
US6331633B1 (en) * 1998-05-08 2001-12-18 Calyx Therapeutics Inc. Heterocyclic analogs of diphenylethylene compounds
ATE310733T1 (de) * 2000-04-21 2005-12-15 Pfizer Prod Inc Thyroid-rezeptorliganden
US6620830B2 (en) 2000-04-21 2003-09-16 Pfizer, Inc. Thyroid receptor ligands
US6680387B2 (en) 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6768008B2 (en) 2000-04-24 2004-07-27 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
JP2003531200A (ja) * 2000-04-24 2003-10-21 アリックス セラピューティクス 糖尿病、高脂血症、高コレステロール血症、およびアテローム性動脈硬化症の治療のための材料と方法
JP2003040877A (ja) * 2001-07-24 2003-02-13 Sumika Fine Chemicals Co Ltd ５−［６−（２−フルオロベンジルオキシ）−２−ナフチル］メチル−２，４−チアゾリジンジオンの製造方法及びその精製方法
PL2001468T3 (pl) 2006-03-16 2013-03-29 Metabolic Solutions Dev Co Llc Analogi tiazolidynodionu
PL2001469T3 (pl) 2006-03-16 2012-10-31 Metabolic Solutions Dev Co Llc Analogi tiazolidynodionu
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
AU2008301905B2 (en) 2007-09-14 2013-06-27 Cirius Therapeutics, Inc. Thiazolidinedione analogues for the treatment of hypertension
WO2011084453A1 (en) 2009-12-15 2011-07-14 Metabolic Solutions Development Company Ppar-sparing thiazolidinedione salts for the treatment of metabolic diseases
HUE030263T2 (hu) 2010-04-19 2017-04-28 Octeta Therapeutics Llc Új szintézis tiazolidindion vegyületek elõállítására
KR20130064742A (ko) * 2010-04-21 2013-06-18 메타볼릭 솔루션스 디벨롭먼트 컴퍼니, 엘엘씨 티아졸리딘디온 유사체
MX349006B (es) 2010-08-10 2017-07-06 Cirius Therapeutics Inc Nueva sintesis para compuestos de tiazolidindiona.
CN115433144B (zh) * 2022-10-09 2023-09-19 燃点(南京)生物医药科技有限公司 一种脂肪酸酯类化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat

Also Published As

Publication number Publication date
DK0549365T3 (da) 1995-12-18
EP0549365B1 (en) 1995-08-09
EP0549365A1 (en) 1993-06-30
CZ389792A3 (en) 1994-01-19
FI925849A0 (fi) 1992-12-23
ATE126221T1 (de) 1995-08-15
NO924964L (no) 1993-06-28
CN1032751C (zh) 1996-09-11
FI925849A (fi) 1993-06-27
HU9204130D0 (en) 1993-04-28
CN1074680A (zh) 1993-07-28
TW211007B (hu) 1993-08-11
NO302471B1 (no) 1998-03-09
RU2095354C1 (ru) 1997-11-10
DE69204041D1 (de) 1995-09-14
AU3043192A (en) 1993-07-01
CA2086277A1 (en) 1993-06-27
JPH05239041A (ja) 1993-09-17
IL104238A (en) 1996-10-31
NZ245612A (en) 1994-06-27
NO924964D0 (no) 1992-12-22
ES2078671T3 (es) 1995-12-16
GR3017632T3 (en) 1996-01-31
HU215450B (hu) 1999-04-28
JP2833949B2 (ja) 1998-12-09
HK196095A (en) 1996-01-05
DE69204041T2 (de) 1996-03-28
MX9207595A (es) 1994-06-30
ZA9210021B (en) 1993-07-02
AU654223B2 (en) 1994-10-27

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee